College Football Odds Week 5: South Carolina vs Tennessee Lines, Spreads, Betting Trends
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The Week 5 college football betting odds have the Tennessee Volunteers as double-digit home favorites over the South Carolina Gamecocks in this SEC clash. Coverage begins from Neyland Stadium in Knoxville, Tennessee on Saturday, September 30 at 7:30 p.m. ET on SEC Network.
Here's everything you need to know about the college football odds for Week 5 South Carolina vs Tennessee: the opening lines, spreads, betting trends and more. Check back regularly for updates.
South Carolina vs No. 21 Tennessee Odds

- Opening point spread: Tennessee -11.5
- Opening moneyline: Tennessee -455/South Carolina +345
- Opening total: Over/Under 61 points scored
- Time: 7:30 p.m. ET Saturday (SEC Network)
UPDATE 2:30 P.M. ET FRIDAY: Tennessee opened -11.5 at BetMGM and has spent the week bouncing between -12 and -12.5. The Vols are currently -12.5, though tickets and money are in the 2.5/1 range on the Gamecocks.
Early moneyline bettors are also on South Carolina, which last year stunned Tennessee 63-38 as a hefty 23.5-point home underdog. Moneyline tickets are 5/1 and moneyline cash beyond 9/1 on the Gamecocks.
The total opened at 62.5, topped out at 63.5 Monday and just hit its low point of 60.5 in the past few minutes. The Under is netting 60% of early tickets/78% of early dollars.
UPDATE 3 P.M. ET MONDAY: After losing at Florida, Tennessee (3-1 SU/2-2 ATS) stepped away from SEC play for a week and got back on track. The Vols rolled over UTSA 45-14 to cash as 24-point home faves.
South Carolina (2-2 SU and ATS) has covered three in a row. But the Gamecocks are probably still smarting after taking a 14-3 halftime lead at Georgia, only to lose 26-14 in Week 3. Still, in Week 4, South Carolina rebounded with a 37-30 win as 6-point home chalk against Mississippi State.
Tennessee is already up a point in Caesars' college football Week 5 odds market, going to -12 and -12.5 this morning. The total climbed a point to 62 Sunday evening.
Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 5 Report containing spreads, lines, and trends for every Top 25 matchup.
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