2025 College Football Week 13 Odds: Lines, Spreads, Betting Trends on Biggest Games

Patrick Everson Sports Betting Expert

9 minute read

The College Football Week 13 odds market features an unusual mix of games, with nothing resembling a marquee matchup.

Still, there are contests with potential CFP ramifications in the college football odds Week 13 market. Among them: USC vs. Oregon, Pitt vs. Georgia Tech and Missouri vs. Oklahoma.

Here’s everything you need to know about college football odds Week 13: opening lines, spreads and betting trends for the biggest games, as multiple oddsmakers provide insights on Week 13 college football odds and action.

Check back regularly for updates and use our bet365 bonus code to get the most out of your action.

(Feature image: Rob Gray/Imagn Images)

2025 College Football Odds for Week 13

Pittsburgh vs. Georgia Tech Odds

• Opening point spread: Georgia Tech -2.5
• Opening moneyline: Georgia Tech 150/Pitt +130
• Opening total: Over/Under 62.5 points scored
• Time: 7 p.m. ET Saturday (ESPN)

Don't make your bets without first looking at Pitt vs. Georgia Tech Predictions!

GAME DAY UPDATE: Forty minues before kickoff, Georgia Tech is -2.5 (-115) in BetMGM's college football odds Week 13 market. In fact, this line has been painted to Yellow Jackets -2.5 all week, with only a couple juice adjustments after opening -2.5 flat.

"We're cheering for the 'dog," BetMGM trading manager Seamus Magee, noting an outright Pitt win would be welcomed, as well.

The total is at 59.5 (Over -118), a low point hit a couple times today, after opening Sunday at 62.5 and spending much of the week at 61.5. Counter to the downward move, though, Magee said BetMGM wants the Under.

LATE WEEK UPDATE: Georgia Tech toggled between -2.5/-3 multiple times early in the week in DraftKings' Week 13 college football odds. The Yellow Jackets went to -2.5 (-115) Tuesday morning and are still there at 3 p.m. ET Thursday.

Early spread play is solidly on Georgia Tech, at 80% of bets/70% of money. Moneyline splits are similarly on the Yellow Jackets.

The total bounced between 62.5/61.5 throughout the week and is now 61.5 (Over -115). It's two-way play with a lean toward the Under, at 56% of bets/58% of money.

EARLY WEEK UPDATE: Borgata Sports opened Georgia Tech as 2.5-point home chalk, and the number remains there Monday night.

"This could certainly get to 3, with most of the early money coming in on the Yellow Jackets," Borgata sportsbook director Tom Gable said. "Georgia Tech found itself in a much-closer-than-anticipated game against Boston College this past Saturday.

"Now, with a win here against Pitt, Georgia Tech will clinch a spot in the ACC championship game. Which of course gives the Yellow Jackets a shot at getting into the CFP."

OPENING ODDS UPDATE: Georgia Tech (9-1 SU/6-4 ATS) nearly suffered its second straight loss, and this time to a team that was 1-9 SU. But the Yellow Jackets escaped Boston College with a 36-34 victory, winning on a waning-seconds field goal.

Georgia Tech fell well short of cashing as 16.5-point road chalk, yet remained atop the ACC standings in its quest for a CFP bid.

Pittsburgh (7-3 SU and ATS) got punished in Week 12, but it wasn't an ACC game, so Pitt remains in the conference title hunt, as well. The Panthers were 13-point home underdogs to Notre Dame and tumbled 37-15.

Pitt-Georgia Tech opened at Yellow Jackets -2.5 in Circa's Week 13 college football odds. There's been no early movement Sunday.

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BYU vs. Cincinnati Odds

• Opening point spread: BYU -2
• Opening moneyline: BYU -125/Cincinnati +105
• Opening total: Over/Under 52.5 points scored
• Time: 8 p.m. ET Saturday (FOX)

Need more info before you wager? Check out VI's BYU vs. Cincinnati Predictions!

GAME DAY UPDATE: Ninety minutes before kickoff, BYU is -2.5 (-115) at BetMGM. Much like Pitt-Georgia Tech, this line has been pinned to Cougars -2.5 almost all week, though it spent a couple hours this morning at -3.

"There's lots of interest in BYU tonight. We're gonna need Cincy +2.5. Outright would be great, too," BetMGM trading manager Seamus Magee said.

The total is at 56.5, reaching that high point this morning after a climb from the 53.5 opener. Magee said the book needs the Under.

LATE WEEK UPDATE: DraftKings has BYU at -2.5 (-115) as of 3 p.m. ET Thursday. In fact, the line has been at some iteration of Cougars -2.5 since Sunday, shortly after opening at -1.5 Sunday.

It's all BYU early on the spread, at 83% of bets/78% of money. The Cougars are getting hit at a similar rate on the moneyline.

DraftKings' total is at 55.5, after opening 53.5, spending the first half of the week at 54.5 and getting to 55.5 Thursday morning. The Over is netting 80% of early bets/67% of early money.

EARLY WEEK UPDATE: BYU opened as 2.5-point road chalk in Borgata Sports' college football Week 13 odds. As of Monday night, the Cougars remain -2.5.

"There’s been some early recreational money on the 'dog," Borgata sportsbook director Tom Gable said. "There is a lot at stake for BYU. With a win, followed by another win against lowly UCF, the Cougars could find themselves in the Big 12 title game, with a shot at the CFP.

"Cincinnati has been a tough team all season, though."

Borgata's total is at 54.5 from a 53.5 opener.

OPENING ODDS UPDATE: BYU (9-1 SU/7-3 ATS) rebounded just fine from its blowout loss at Texas Tech. The Cougars were 3-point home favorites and trucked TCU 44-13, staying in the hunt for the Big 12 title and a possible CFP bid.

Cincinnati (7-3 SU/6-4 ATS) saw its Big 12 title hopes take on serious water in Week 12. The Bearcats tumbled to Arizona 30-24 as 5.5-point home favorites, their second straight setback, following a road loss vs. Utah.

Circa Sports opened BYU -2 in the college football Week 13 odds market. The first move came within minutes to Cougars -2.5.

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USC vs. Oregon Odds

• Opening point spread: Oregon -8
• Opening moneyline: Oregon -340/USC +280
• Opening total: Over/Under 58.5 points scored
• Time: 3:30 p.m. ET Saturday (CBS)

Much more on this matchup in VegasInsider's USC vs. Oregon Predictions piece!

GAME DAY UPDATE: With 50 minutes until kickoff, Oregon is 10.5-point chalk, with BetMGM dealing -105 juice on both sides. The Ducks opened -9.5 (-105) and saw only juice adjustments until going to -10 Thursday/-10.5 Friday.

"We're really just hoping this doesn't land Oregon by exactly 10," BetMGM trading manager Seamus Magee said. "Nothing is a big need for us in this game. Plenty of takers on +10.5 and plenty of people on Oregon -9.5.

"Action seems to be spread decently. But we'll see what action we get in the minutes leading to kickoff, after some of the noon ET games end."

The total is at 59.5, which is where it's been all week, seeing only a couple juice adjustments. Magee said there's not much to it, but the book would prefer the Under.

LATE WEEK UPDATE: As of 2:30 p.m. ET Thursday, the Ducks are 9.5-point home favorites in DraftKings' college football Week 13 odds. That's where the number has been since Tuesday, after opening at Oregon -8.5 and shooting to -10 by Monday afternoon.

Oregon is taking 56% of early spread tickets/65% of early spread money.

DK's total is at 59.5, matching the opener, but down from the 60.5 high point of Sunday afternoon. It's two-way action, with 58% of tickets/54% of money on the Over.

EARLY WEEK UPDATE: Oregon opened and remains -9.5 in Borgata Sports' college football odds Week 13 market.

"Another classic Big Ten game here between USC and Oregon, both with only one loss in the conference," Borgata sportsbook director Tom Gable said, with a little sarcasm and call-out to the old Pac-12. "USC is off probably its best performance of the season in a win against Iowa.

"The USC defense pitched a shutout in the second half, and the Trojan playmakers came alive when they needed to. Obviously, Oregon is a step up from Iowa."

OPENING ODDS UPDATE: Oregon (9-1 SU/5-4-1 ATS) easily stayed on track for a College Football Playoff bid in Week 12. The Ducks drilled Minnesota 42-13 laying 26.5 points at home.

Southern Cal (8-2 SU/5-5 ATS) dug itself into first-half holes of 14-0 and 21-7 vs. Iowa. But the Trojans scored the final 20 points of the game in a 26-21 victory giving 6.5 points at home.

USC probably won't reach the Big Ten title game nor the CFP, but can make things messy for the Ducks.

Circa opened Oregon as 8-point home chalk in the college football odds Week 13 market. In very short order Sunday, the Ducks advanced to -9.5

Missouri vs. Oklahoma Odds

• Opening point spread: Oklahoma -10
• Opening moneyline: Oklahoma -340/Missouri +280
• Opening total: Over/Under 44.5 points scored
• Time: Noon ET Saturday (ABC)

Before you bet, check out VegasInsider's College Football Week 13 Predictions!

GAME DAY UPDATE: With 40 minutes to go until kickoff, Oklahoma is down to -5.5 (-115) in BetMGM's college football Week 13 odds. On Sunday, the Sooners opened -9.5, and the line dipped to -8.5/-7.5 Monday.

With late-week news that Missouri QB Beau Pribula is expected to play, the spread dipped to -7 Thursday night, -6.5 Friday afternoon and -5.5 Friday night. Still, BetMGM is rooting for the underdog today.

"We're gonna need Mizzou +5.5. Sharps pushed this through 7 with the news of Pribula starting for Mizzou. But once this number touched Oklahoma -5.5, the public has been all over the Sooners," BetMGM trading manager Seamus Magee said.

"Nothing sharp enough to push us off 5.5, though. We would like to see this game stay Under 42.5, as well."

The total is at 42.5 (Over -115), after opening 42.5 flat and spending Wednesday night-early Friday at 41.5.

LATE WEEK UPDATE, PART II: Thursday evening brought news that Missouri QB Beau Pribula might start this week, after missing two games with a dislocated left ankle. And the market responded, with Oklahoma dipping from -7.5 (-105) to -7 (-115)/-6.5 (-115) at DraftKings.

As of 6:30 p.m. ET Friday, the Sooners are -6.5 (-108), after opening -9.5 and spending much of the week at -7.5. Oklahoma is netting 70% of spread bets at DK, but 55% of spread money is on road 'dog Missouri.

Also Thursday evening, the total went from 41.5 to 42.5, and it's now 42.5 (Over -115), after opening at 42.5 flat. The Over is getting 80% of bets, but just 53% of money.

LATE WEEK UPDATE: The Sooners dropped from -9.5 Sunday to -8.5/-7.5 Monday in DraftKings Sportsbook's college football odds Week 13 market. Since then, there have been a couple juice adjustments, and Oklahoma is at -7.5 flat as of 2:30 p.m. ET Thursday.

There's a significant disparity in early spread betting splits. Oklahoma is taking 60% of tickets so far, but 77% of cash is on road underdog Missouri.

DraftKings' total is at 41.5, where it's been since Tuesday after opening at 42.5. That said, 87% of tickets/79% of dollars are on the Over.

EARLY WEEK UPDATE: Oklahoma opened -9.5 and saw no movement until Monday afternoon in Borgata Sports' college football Week 13 odds. Then came two dips in close succession, to Sooners -8.5/-7.5.

"We're essentially moving with the broader market," Borgata sportsbook director Tom Gable said. "I haven’t seen anything significant here of sharp money taking Missouri at 9.5 or 8.5."

Borgata's total opened and remains 42.5.

OPENING ODDS UPDATE: Oklahoma (8-2 SU/6-4 ATS) faced an absolute must win in Week 12, and absolutely won. The Sooners' defense turned up the heat on Alabama, forcing three turnovers, and OU hung on for a 23-21 victory catching 6.5 points on the road.

Missouri (7-3 SU/6-4 ATS) is likely just looking to play SEC spoiler at this point. In Week 12, the Tigers thumped Mississippi State 49-27 laying 7.5 points at home.

Circa Sports' opening numbers are well-respected and often generate sharp action right out of the gate. Circa opened Oklahoma -10 and dipped to -9.5 within minutes Sunday in college football Week 13 odds. The total was a bigger mover, falling from 44.5 to 42.5 in a hurry.

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson