NFL Odds Week 2: Lines, Spreads, Betting Trends For All 16 Games

Patrick Everson Sports Betting Expert

28 minute read

2025 NFL Odds Week 2

NFL odds for Week 2 head to the final two games, with a double dose of Monday night Football.

Tampa Bay Buccaneers vs. Houston Texans is up first Monday. That's followed by Los Angeles Chargers vs. Las Vegas Raiders to wrap up odds for NFL Week 2.

Here’s everything you need to know about the NFL odds Week 2 market: opening lines, spreads and betting trends for every game, as multiple oddsmakers provide insights on NFL Week 2 odds and action. Check back regularly for updates and use our bet365 bonus code to get the most out of your action.

(Feature image: Kim Klement Neitzel/Imagn Images)

NFL Odds for Every Game of NFL Week 2

Los Angeles Chargers vs. Las Vegas Raiders Odds

• Opening point spread: Chargers -3
• Opening moneyline: Chargers -180/Raiders +150
• Opening total: Over/Under 44.5 points scored
• Time: 10 p.m. ET Monday (ESPN)

GAME DAY LATE UPDATE: BetMGM has the Chargers at -3.5 (-105) in NFL Week 2 odds, with 75 minutes until kickoff. Eight days ago, the Chargers opened as 3-point road favorites.

In digital wagering (mobile/online), it's heavy Chargers play at BetMGM. Los Angeles is taking 65% of spread bets/71% of spread money. On the moneyline, it's 57% bets/69% money on the Chargers.

"We'll be rooting for the Raiders, for sure," BetMGM trading manager Christian Cipollini said.

The total is at 46.5 from a 44.5 opener, with 69% of bets/81% of money on the Over. So no surprise, the book will need the Under in this late-night AFC West clash.

GAME DAY EARLY UPDATE: With 7.5 hours until kickoff, the Chargers are -3.5 (-105) in DraftKings' Week 2 NFL odds. Throughout the past eight days, the Chargers have toggled between the -3.5 opener and -3, at various juice.

Spread tickets are running 2.5/1 and spread money 2/1 on Los Angeles. And DK moneyline bettors are on the Chargers, as well, with tickets 8/1 and money 4/1.

DraftKings' total is up to 46.5 (Over -118) from a 44.5 opener. Ticket count is 1.5/1 and money 3/1 on the Over.

MIDWEEK UPDATE: Los Angeles opened and remains -3.5 in Borgata Sports' NFL Week 2 odds, as of Wednesday afternoon. All that's changed is a modest juice adjustment, to Chargers -3.5 (-105).

"The Chargers are coming off more rest, but also back from Brazil after their Week 1 win against the Chiefs," Borgata sportsbook director Tom Gable said. "The Raiders had a nice upset win against the Patriots, which was a decent result for us.

"It’s been mostly early Chargers money here. But this game doesn’t have a lot written on it yet."

The total is on the rise, climbing to 47 from a 44.5 opener.

OPENING ODDS UPDATE: Los Angeles (1-0 SU and ATS) kicked off its season in good form in a neutral-site game at Sao Paulo, Brazil. The Chargers, behind a sterling night from QB Justin Herbert, beat Kansas City 24-20 catching 3 points.

Las Vegas (1-0 SU and ATS) got Pete Carroll's return to coaching off to a good start. The Raiders held off New England 20-13, cashing as 2.5-point road 'dogs.

Los Angeles opened -3 and adjusted to -3 (-120) Sunday night in The SuperBook's NFL odds Week 2 market.

"No action to report yet. Both teams have to be very pleased with their start to the season. It should be a good one here in Las Vegas" SuperBook vice president John Murray said.

In-Progress Games for NFL Week 2

Tampa Bay Buccaneers vs. Houston Texans Odds

• Opening point spread: Texans -2.5
• Opening moneyline: Texans -130/Buccaneers +110
• Opening total: Over/Under 44.5 points scored
• Time: 7 p.m. ET Monday (ABC)

GAME DAY LATE UPDATE: Kickoff is 30 minutes out, and the Texans are -2.5 (-115) in BetMGM's NFL odds Week 2 market. That's up a point from the opener of Houston -1.5.

The Texans are taking slightly more action on the spread, but the Bucs are popular on the moneyline. So BetMGM is hoping to thread the needle of a Houston win by 1 or 2 points.

"It's a tight window, but Texans win and no cover would be ideal," BetMGM trading manager Christian Cipollini said.

The total is down to 42.5 from a 46.5 opener. Still, Cipollini said BetMGM prefers the Under, which is the norm, especially in prime-time games.

GAME DAY EARLY UPDATE: With five hours until kickoff, the Texans are 2.5-point home favorites in DraftKings Sportsbook's NFL Week 2 odds. That's where the line has been pretty much all week, after opening Houston -1.5 eight days ago.

Point-spread opinions are split on this matchup, with 65% of bets on the Buccaneers and 70% of money on the Texans at DK. On the moneyline, it's 71% bets on Tampa/55% money on Houston.

DraftKings' total is painted to 42.5, not moving off that number all week. And that's with 77% of bets/82% of money on the Over.

MIDWEEK UPDATE: Houston opened -1.5 and is up to -2.5 in Borgata Sports' NFL odds Week 2 market.

"That's where I think this game will probably end up staying," Borgata sportsbook director Tom Gable said Wednesday. "With the doubleheader on Monday night, you’ll see a lot more parlays between the two games.

"And these two games might not necessarily be included [in parlays] with the Sunday games, [opposite what] you normally would see when you only get one Monday night game."

The total is all the way down to 42.5 from a 46.5 opener.

OPENING ODDS UPDATE: Houston (0-1 SU and ATS) had little to offer offensively in a 14-9 Week 1 loss to the L.A. Rams. The Texans managed just three field goals, all in the first half, while failing to cash as 3-point road underdogs.

Tampa Bay (1-0 SU and ATS) got a jump-start in defense of its NFC South title. The Bucs scored a touchdown with 59 seconds left and survived the missed extra point to beat Atlanta 23-20 as 1-point road favorites. The Falcons missed a 44-yard field goal in the waning seconds.

"We opened this one Texans -2.5 and are now at -1.5, after seeing a little money trickle in on the Bucs," SuperBook VP John Murray said Sunday night. "What a win that was for Baker Mayfield and Tampa today.

"This is a good early Monday Night Football matchup, between two teams that expect to be in the playoffs."

Completed Games for NFL Week 2

Atlanta Falcons vs. Minnesota Vikings Odds

• Opening point spread: Vikings -4.5
• Opening moneyline: Vikings -225/Falcons +185
• Opening total: Over/Under 45.5 points scored
• Time: 8:20 p.m. ET Sunday (NBC)

GAME DAY UPDATE: With kickoff an hour out, Minnesota is -3.5 (-105) in BetMGM's NFL odds Week 2 market. That's down a point from the opener of Vikings -4.5, but the Vikes were -3 this morning.

In digital betting (online/mobile) at BetMGM, 59% of spread bets are on Minnesota, while 73% of dollars are on Atlanta.

The total is at 44.5 from a 45.5 opener, but per usual, it's a prime-time game in which the public is on the Over. Ticket count is 2/1 and money almost 3/1 on the Over.

MIDWEEK UPDATE: This line has done a little back-and-forth in Borgata Sports' Week 2 NFL odds. The Vikings opened -4.5 and got to -5.5, but are now back at -4.5.

"The Vikings have already been included in a lot of parlays. And with this being the Sunday night game, I expect to see that trend continue," Borgata sportsbook director Tom Gable said. "This is an intriguing match up between these two quarterbacks.

"In Week 1, we had one of our bigger decisions of the week in the Tampa-Atlanta game, with a lot of respected money piling in on Atlanta later, when limits went up."

The total is down to 44.5 from a 45.5 opener.

EARLY WEEK UPDATE: Minnesota (1-0 SU and ATS) did its best Monday night to mimic Buffalo's thrilling Sunday night win. The Vikings trailed 17-6 into the fourth quarter, then put up three touchdowns to beat Chicago 27-24 as 1-point road underdogs.

On Sunday night, The SuperBook opened Falcons-Vikings at Minnesota -4.5 and quickly went to -5.5. On Tuesday morning, the Vikings inched down to -5, as they play their second straight prime-time game, this time on short rest.

OPENING ODDS UPDATE: Atlanta (0-1 SU and ATS) lost its 2025-26 debut in heartbreaking fashion. Younghoe Koo missed a 44-yard field in the waning seconds, and the Falcons fell 23-20 as 1-point home 'dogs.

Minnesota hasn't finished its Week 1 assignment. The Vikings visit Chicago in the Monday night game.

Minnesota opened as 4.5-point home chalk vs. Atlanta in The SuperBook's NFL Week 2 odds. The Vikes then moved out to -5.5 Sunday night.

"Atlanta let one get away today at home. But the Falcons will be getting the Vikings off a short week. It's a good early test for both teams," SuperBook VP John Murray said.

Denver Broncos vs. Indianapolis Colts Odds

• Opening point spread: Broncos -3
• Opening moneyline: Broncos -155/Colts +130
• Opening total: Over/Under 43.5 points scored
• Time: 4:05 p.m. ET Sunday (CBS)

GAME DAY UPDATE: Thirty minutes before kickoff, Denver is a 2.5-point road favorite in BetMGM's NFL Week 2 odds. That's down a point from the opener of Broncos -3.5.

Still, the book will needs the home 'dog today.

"We're gonna be rooting for the Colts here," BetMGM trading manager Christian Cipollini said.

The total is down to 43.5 (Under -115) from a 44.5 opener. But Cipollini said BetMGM still needs the Under, due to parlays and more so single-game parlays.

MIDWEEK UPDATE: As of Thursday night, the Broncos are down to -1.5 (-115) in DraftKings' NFL odds Week 2 market, after opening -3.5. Denver toggled between -2.5/-1.5 at various juice on Wednesday/Thursday.

The Broncos are seeing 62% of spread tickets, while 58% of spread money is on the Colts.

DK's total is down to 42.5 (Over -118) from a 44.5 opener. It's been at some iteration of 42.5 since Tuesday. Action is mixed, with 56% of tickets on the Over/67% of money on the Under.

OPENING ODDS UPDATE: Denver (1-0 SU/0-1 ATS) was widely expected to roll as an 8.5-point favorite vs. Tennessee. But the Broncos needed a late TD to put the game away in a 20-12 home victory.

Indianapolis (1-0 SU and ATS) was much more convincing in Week 1. The Colts hammered Miami 33-8 laying 1.5 points at home.

Broncos-Colts opened at Denver -3 and is down to -2.5 in The SuperBook's Week 2 NFL odds. The total hasn't moved off 43.5.

Carolina Panthers vs. Arizona Cardinals Odds

• Opening point spread: Cardinals -7
• Opening moneyline: Cardinals -278/Panthers +225
• Opening total: Over/Under 45.5 points scored
• Time: 4:05 p.m. ET Sunday (CBS)

GAME DAY UPDATE: Arizona is 7-point chalk in DraftKings Sportsbooks' NFL odds Week 2 market, up from a -6.5 opener. The Cardinals are landing 67% of spread bets/76% of spread dollars.

DK opened the total at 45.5 and that's where the number is now. the Under is getting 59% of bets and 85% of money.

MIDWEEK UPDATE: The Cardinals have spent the week toggling between -6.5/-7 in DraftKings' Week 2 NFL odds. As of Thursday night, Arizona is -6.5 (-115), with ticket count 2/1 and money 3/1 in the early going.

DK opened the total at 44.5, bottomed out at 43.5 (Over -115) and is now at 44.5 (Under -115). Early ticket count is 1.5/1 on the Under, but early money is almost 9/1 on the Over.

OPENING ODDS UPDATE: Arizona (1-0 SU and ATS) didn't light it up in Week 1 vs. a New Orleans squad expected to be the worst in the NFL. But the Cards got out of town with a 20-13 road win laying 5.5 points.

Carolina (0-1 SU and ATS) couldn't find the end zone until late in the fourth quarter against Jacksonville. As such, the Jags lost 26-10 catching 4.5 points on the road.

Arizona opened -6.5 at The SuperBook and is already up to -7 Sunday night.

Philadelphia Eagles vs. Kansas City Chiefs Odds

• Opening point spread: Eagles -1
• Opening moneyline: Eagles -120/Chiefs even
• Opening total: Over/Under 45.5 points scored
• Time: 4:25 p.m. ET Sunday (FOX)

GAME DAY LATE UPDATE: With kickoff 45 minutes out, the Eagles are -1 (-115) in BetMGM's Week 2 NFL odds. That's down a tick from the opener of Philly -1.5, but the road favorite is getting plenty of attention.

"We're gonna be rooting for the Chiefs at home. I can't think of many times that's happened. It's probably been under three times since 2020," BetMGM trading manager Christian Cipollini said.

The total is up to 47 from a 45.5 opener, and Cipollini said BetMGM needs the Under, per usual.

GAME DAY EARLY UPDATE: This contest is easily the marquee matchup of the week. Philadelphia opened -1.5 in DraftKings Sportsbook's NFL Week 2 odds, and that's where the line sits five hours before kickoff.

Spread play is solidly on Philly, with tickets running 3/1 and money 2/1.

DK's total is at 46.5 (Over -118), after opening 45.5 last Sunday. Tickets and money are approaching 3/1 on the Over.

LATE WEEK UPDATE: On Sunday, Philly opened -1.5 in ESPNBET's Week 2 NFL odds, and that's where the line sits Friday afternoon. In between, though, the line made a foray to K.C. being the favorite.

"The Super Bowl rematch is our most-bet game of the weekend," ESPNBET senior director of sports trading Adrian Horton said. "We briefly flipped to Chiefs -1.5 on Tuesday. But it's been steady action on the Eagles to move back to where we opened, with Philly as a slight favorite."

Philadelphia is now -1.5 (-105). When accounting for both straight bets and parlays, spread action is almost 3/1 and spread money 2.5/1 on the Eagles. Further, moneyline action is on Philly, with tickets 3/1 and money 2/1.

ESPNBET opened the total at 46.5 and is at 46.5 (Over -115) Friday afternoon. Ticket count is 2.5/1 and money 2/1 on the Over, again accounting for both straight bets and parlay play.

MIDWEEK UPDATE: Borgata Sports pegged this game a pick 'em at opening, and it's now Eagles -1 in NFL Week 2 odds.

"The Super Bowl rematch will probably end up being the game with the most written on it, when it’s all said and done," Borgata sportsbook director Tom Gable said. "We’ve had a decent amount of Eagles money early, and I’m pretty confident we will end up needing the Chiefs here."

With Borgata in Atlantic City, a stone's throw from Philly, there's certainly some regional bias in the action, as well.

Borgata's total is up up to 47 from a 45.5 opener.

"We are starting to see a little bit of money come in on the Under at 47," Gable said.

OPENING ODDS UPDATE: Philadelphia (1-0 SU/0-1 ATS) was a solid 8-point home favorite vs. Dallas, in the Thursday kickoff to the regular season. But the Eagles had their hands full all night, ultimately prevailing 24-20 while failing to cover.

Kansas City (0-1 SU and ATS), the three-time defending AFC champion, saw its 2025-26 campaign get off to a bumpy start. The Chiefs fell to the L.A. Chargers 24-20, with K.C. 3-point chalk on neutral turf in Sao Paulo, Brazil on Friday.

"The Chiefs were a small favorite on the lookahead number last week. But we opened Philly -1 after seeing Kansas City struggle on Friday night in Brazil," SuperBook VP John Murray said Sunday night. "I’ll be interested to see how the public plays this game.

"Yes, Kansas City is off a loss, and yes, the Eagles destroyed them back in February. But the Eagles had their own struggles in Week 1 and could easily be 0-1 themselves."

Buffalo Bills vs. New York Jets Odds

• Opening point spread: Bills -7.5
• Opening moneyline: Bills -340/Jets +270
• Opening total: Over/Under 44.5 points scored
• Time: 1 p.m. ET Sunday (CBS)

GAME DAY UPDATE: With kickoff about 75 minutes out, the Bills are 6-point chalk in BetMGM's NFL odds Week 2 market. That's notably down from the Buffalo -8.5 opener last weekend.

In digital spread betting (online/mobile), the Bills are getting 66% of tickets, while 55% of money is on the home underdog Jets. Interestingly, the Bills are taking the most spread tickets today, while the Jets are drawing the most spread money.

BetMGM trading manager Christian Cipollini said the Jets are key today, along with fellow 'dogs Chicago, at Detroit, and the New York Giants, at Dallas.

"We need all the 'dogs. A cover is enough, but one of them winning outright would be even better. Very lopsided action on all three of those favorites," BetMGM trading manager Christian Cipollini said.

BetMGM's total climbed from 44.5 to 47.5, with one-way traffic on the Over, at 75% of tickets/90% of money.

MIDWEEK UPDATE: DraftKings Sportsbook has Buffalo as 6.5-point chalk on Thursday night. That's down a point from the Bills -7.5 Sunday opener, with the line at various iterations of -6.5 since Wednesday afternoon.

Spread play is interesting at this point, with ticket count 2/1 on the Bills and money 3/1 on the home 'dog Jets.

DK's total is stable at 46.5, although early tickets are 4/1 and early dollars 8/1 on the Over.

OPENING ODDS UPDATE: Buffalo made an absolutely jaw-dropping comeback in the first Sunday night game of the season. The Bills trailed Baltimore 40-25 with under five minutes remaining, but rallied for a stunning 41-40 victory as 1.5-point home underdogs.

Matt Prater, subbing for the injured Tyler Bass, secured the win on a 32-yard field goal as time expired.

New York (0-1 SU/1-0 ATS) hung with Pittsburgh all day, taking a 26-17 lead on a late-third-quarter TD. But the Jets couldn't make it hold up, losing 34-32 on a final-seconds 60-yard field goal. On the bright side, New York covered as a 3-point home pup.

Bills-Jets opened at Buffalo -7.5 in The SuperBook's NFL Week 2 odds, with a total of 44.5. The total nudged to 45 shortly thereafter Sunday night. The matchup was then taken off the board once Ravens-Bills kicked off. Bills-Jets will go back up Monday morning.

Chicago Bears vs. Detroit Lions Odds

• Opening point spread: Lions -4.5
• Opening moneyline: Lions -205/Bears +170
• Opening total: Over/Under 47.5 points scored
• Time: 1 p.m. ET Sunday (FOX)

GAME DAY UPDATE: In the wake of Chicago's Week 1 Monday night late collapse vs. Minnesota, this line has moved toward Detroit. The Lions opened -4.5 in BetMGM's NFL Week 2 odds, and they're now up to -6.5.

Spread ticket count is 2/1 and spread money 2.5/1 on the Lions. Moneyline play is almost dead even on tickets and money.

BetMGM's total is at 46, down a notch from the 46.5 opener. Still, tickets are just shy of 2/1 and money is 5/1 on the Over.

MIDWEEK UPDATE: Detroit is out to 6-point chalk in DraftKings' NFL odds Week 2 market, after opening -4.5. It's solid Lions spread play early, at 67% of bets/81% of money on Thursday night.

"A cover is enough, but [Chicago] winning would be even better," BetMGM trading manager Christian Cipolli said.

The total opened at 48.5 and spent time at 47.5 (Over -115) on the way to 46.5 Wednesday. Bet count is dead even, while 62% of money is on the Over.

EARLY WEEK UPDATE: Chicago (0-1 SU and ATS) actually appeared set to start the season on a strong note. The Bears led the visiting Vikings 17-6 through three quarters on Monday night.

But then things went awry, as Chicago allowed three fourth-quarter TDs and lost 27-24 laying 1 point at home.

On Sunday night, The SuperBook opened Bears vs. Lions at Detroit -4.5. On Tuesday morning, in the wake of Chicago's loss, The SuperBook moved Detroit to -5.5.

OPENING ODDS UPDATE: Detroit (0-1 SU and ATS) has been a spread-covering machine the last 2.5 seasons, at 35-12-1 ATS heading into Week 1. But the Lions couldn't solve Green Bay, losing 27-13 as 1.5-point road underdogs. Detroit didn't get a touchdown until the final minute.

Chicago still has Week 1 work to do, hosting Minnesota in the Monday night game. But that didn't stop The SuperBook from posting a line in its NFL odds Week 2 market.

"We took some lookahead money last week on the Bears at +5.5. After the Lions looked all out of sorts this afternoon, we re-opened the game at Lions -4.5. Not much to report on it yet," SuperBook vice president John Murray said Sunday night.

Likewise, the total is steady at 47.5.

New York Giants vs. Dallas Cowboys Odds

• Opening point spread: Cowboys -4.5
• Opening moneyline: Cowboys -218/Giants +180
• Opening total: Over/Under 44.5 points scored
• Time: 1 p.m. ET Sunday (FOX)

GAME DAY UPDATE: BetMGM has Dallas -5.5, after opening -3 last Sunday. It's all Cowboys on the spread, at 79% of bets/81% of money. In fact, Dallas is taking the second-most tickets and dollars of all teams in Week 2 NFL odds.

BetMGM trading manager Christian Cipollini said a Giants cover is helpful. But the book really needs an outright underdog today, most notably either the G-Men or the Jets or the Bears.

The total is at 45, a tick above the 44.5 opener. It's two-way action, with 56% of bets on the Over/53% of cash on the Under.

MIDWEEK UPDATE: Dallas opened -3.5 at Borgata Sports. Then came news Monday that New York coach Brian Daboll will again start Russell Wilson, despite the veteran QB's lackluster performance in a Week 1 loss at Washington.

"This was another game where a quarterback announcement had a significant impact on line movement," Borgata sportsbook director Tom Gable said, tying this matchup to the 49ers-Saints game. "The Giants attracted a lot of interest in Week 1 against the Commanders.

"But with the way Russell Wilson looked, people were definitely looking forward to Jaxson Dart potentially getting the start here against Dallas. After Coach Daboll announced that Wilson would be the starter, you saw this number move to where it currently sits at Cowboys -6."

That said, there is noteworthy two-way spread play in NFL Week 2 odds.

"So far, this is the most heavily bet game of the week, with money coming in on both sides," Gable said.

The total hasn't moved off 44.5.

OPENING ODDS UPDATE: Dallas (0-1 SU/1-0 ATS) gave defending Super Bowl champion Philadelphia all it could handle in the Week 1 Thursday night game. The Cowboys came up short 24-20, but cashed as 8-point road underdogs.

New York (0-1 SU and ATS) couldn't get its offense on track under new QB Russell Wilson. The Giants netted just two field goals in a 21-6 loss to Washington catching 6 points on the road.

The SuperBook opened Dallas -4.5 in Week 2 NFL odds, with no movement Sunday night. And the total was stable, too, at 44.5.

San Francisco 49ers vs. New Orleans Saints

• Opening point spread: 49ers -7
• Opening moneyline: 49ers -220/Saints +180
• Opening total: Over/Under 43 points scored
• Time: 1 p.m. ET Sunday (FOX)

GAME DAY UPDATE: The 49ers are down to -3 (-105) in BetMGM's Week 2 NFL odds, well off the -7 opener. That's almost entirely due to San Fran QB Brock Purdy (toe/shoulder) being out this week and perhaps longer.

Most of the line movement came by midweek. And the Niners are still seeing 76% of spread bets/78% of spread dollars, two hours before kickoff.

Purdy's absence also impacted the total, down to 40.5 from a 44.5 opener. The Under is seeing 67% of bets/70% of money.

LATE WEEK UPDATE: ESPNBET opened the Niners -7.5, but midweek, this line tumbled to its low point of -3.5 on the news of Brock Purdy being out. On Friday afternoon, San Francisco remains -3.5.

Purdy (toe/shoulder) could miss multiple weeks. In addition, San Fran tight end George Kittle (hamstring) is on injured reserve.

When accounting for all spread play – straight bets and parlays – San Fran is still seeing 72% of tickets and 69% of money. Early moneyline action is tilted even more heavily to the Niners, at 90% of tickets/79% of money.

ESPNBET opened the total at 43.5 and on Friday afternoon sits at 40.5 (Under -115). Accounting for both straight bets and parlay play, 61% of tickets are on the Under, while 58% of money is on the Over.

MIDWEEK UPDATE: This matchup is among the biggest movers this week, due to San Francisco's injury situation. First, tight end George Kittle (hamstring) was ruled out vs. New Orleans and could miss a few games.

Bigger still, quarterback Brock Purdy (toe/shoulder) is considered unlikely to play in Sunday's road tilt. The Niners opened -7 in Borgata Sports' NFL odds Week 2 market, but have slid significantly since.

"The opener obviously was prior to all of the San Francisco injury news," Borgata sportsbook director Tom Gable said late Wednesday morning, before Purdy was ostensibly ruled out. "While Kittle is a key piece, it’s really the difference between Brock Purdy and Mac Jones that you’ve seen, with how this number adjusted.

"It’s now down to San Francisco -4.5. We have seen some bettors buying on San Fran right now, hoping that Purdy will play."

Those hopes were likely squelched Wednesday afternoon, when Niners coach Kyle Shanahan termed Purdy a long shot to play Sunday.

That led Borgata to drop the Niners to -3 against a Saints team that might have a shot. In the offseason, New Orleans was widely expected to be the NFL's worst. But the Saints hung around in Week 1 vs. Arizona.

"The Saints, and in particular QB Spencer Rattler, didn’t look as bad as necessarily projected in Week 1," Gable said. "So if it is in fact Mac Jones who gets the start for the Niners, it will be interesting to see how the market reacts and if we get some New Orleans money."

San Fran's injury issues hit the total, as well, with Borgata opening at 44.5 and now down to 40.5.

OPENING ODDS UPDATE: San Francisco (1-0 SU and ATS) scratched out a 17-13 win over Seattle in Week 1. The Niners got a touchdown with 1:34 remaining to clinch the win and cash as 2.5-point road faves.

New Orleans (0-1 SU and ATS) lost to Arizona 20-13 as 5.5-point home underdogs. That result was widely expected, with the Saints running out second-year QB Spencer Rattler as the starter. But Rattler fared OK, throwing for 214 yards, with no interceptions.

The SuperBook opened the 49ers -7 Sunday night, and that number fell to -6 in short order. The total also moved, from 43 to 43.5.

Cleveland Browns vs. Baltimore Ravens Odds

• Opening point spread: Ravens -12.5
• Opening moneyline: Ravens -750/Browns +525
• Opening total: Over/Under 44.5 points scored
• Time: 1 p.m. ET Sunday (CBS)

GAME DAY UPDATE: Baltimore is the biggest favorite on the NFL Week 2 odds board, currently -12.5 at BetMGM, as of 11 a.m. ET. That matches last weekend's opening number, and it's up a point today, after sitting at Ravens -11.5 earlier this morning.

That said, it's not hugely lopsided spread play. The Ravens are getting 54% of spread tickets/66% of spread money. For those keeping tabs on Circa Survivor, Baltimore is the second-most-chosen team for Week 2, behind only Arizona.

BetMGM's total was 45 earlier this morning and is now 45.5, after opening 44.5. The Over is taking 74% of tickets/82% of money.

MIDWEEK UPDATE: The Ravens opened as 12.5-point favorites in DraftKings' NFL odds Week 2 market. Baltimore has been at -11.5 since Wednesday afternoon on two-way spread play: 58% of bets on the Ravens/52% of money on the Browns.

The total toggled between 44.5/45.5 a couple times this week and is at 45.5 (Under -115) Thursday night. Tickets and money are in the 2/1 range on the Over.

OPENING ODDS UPDATE: Baltimore was running up and down the field all Sunday night at Buffalo, leading 40-25 with under five minutes left. But the Ravens stunningly let the Bills come back, in part due to a Derrick Henry fumble, as Baltimore lost 41-40 on a final-seconds field goal.

The Ravens (0-1 SU and ATS) drew sharp money at books across the country, and the public was on Baltimore, as well. But Lamar Jackson & Co. fell and failed to cover as 1.5-point favorites.

Cleveland (0-1 SU/1-0 ATS) closed as 4.5-point home 'dogs vs. Cincinnati, yet led 16-14 midway through the third quarter. Joe Flacco hit Cedric Tillman on a 5-yard TD pass to put the Browns ahead.

But Cleveland gave up a late-third-quarter field goal and lost 17-16, with neither team scoring in the fourth quarter.

Baltimore opened -12.5 vs. Cleveland, with a total of 44.5. The game then came off the board once Ravens-Bills kicked off Sunday night. Ravens-Browns will go back up Monday morning.

Jacksonville Jaguars vs. Cincinnati Bengals Odds

• Opening point spread: Bengals -4.5
• Opening moneyline: Bengals -192/Jaguars +160
• Opening total: Over/Under 49.5 points scored
• Time: 1 p.m. ET Sunday (CBS)

GAME DAY UPDATE: BetMGM has the Bengals down to -3.5 (-105), after opening -5.5 last Sunday. Still, tickets and money are in the 2/1 range on Cincinnati. Similarly, moneyline tickets are 2/1 and moneyline dollars almost 3/1 on the favored Bengals.

Ninety minutes before kickoff, the total is at 49.5, the highest in NFL odds Week 2. Ticket count is 2/1 and money almost 4/1 on the Over.

MIDWEEK UPDATE: Cincy is -3 (-118) on Thursday night in DraftKings' NFL odds Week 2 market. That's notably down from the opener of Bengals -4.5, with the line going from -3.5 to -3 this evening.

Cincinnati is taking 67% of early spread bets/54% of early spread cash. Moneyline bettors are leaning more into the Bengals, at 84% of bets/83% of money.

DK opened the total at 49.5 and is now at 48.5 (Over -115), with two-way bet count and 78% of money on the Over.

OPENING ODDS UPDATE: Cincinnati (1-0 SU/0-1 ATS) was lucky to escape Week 1 with a victory. The Bengals didn't get much offense, but it was enough to edge Cleveland 17-16 as 4.5-point road favorites. Neither team scored in the fourth quarter.

Jacksonville (1-0 SU and ATS) got its 2025 campaign off to a satisfactory start. The Jaguars built a 20-0 halftime lead vs. Carolina and coasted to a 26-10 victory laying 4.5 points at home.

Bengals-Jags opened at Cincy -4.5 in The SuperBook's NFL Week 2 odds. The line was quickly on the move, dipping to Bengals -3.5 Sunday night. The total is stable at 49.5.

Seattle Seahawks vs. Pittsburgh Steelers Odds

• Opening point spread: Steelers -2.5
• Opening moneyline: Steelers -148/Seahawks +124
• Opening total: Over/Under 40.5 points scored
• Time: 1 p.m. ET Sunday (FOX)

GAME DAY UPDATE: Ninety minutes pre-kick, the Steelers are -3.5 (-105) in BetMGM's NFL Week 2 odds. That's up a point from the opener of Pittsburgh -2.5, with spread tickets and money running 3/1 on the Steelers.

The total is down to 40.5 from a 41.5 opener, with 61% of tickets on the Over/54% of money on the Under.

MIDWEEK UPDATE: DraftKings opened the Steelers as 2.5-point home chalk and has been at some iteration of -3 since Monday. On Thursday night, Pittsburgh is at -3 flat while taking 70% of spread tickets/56% of spread cash.

The Steelers are also a popular moneyline play, at 82% of tickets/77% of money.

DK's total is at 39.5 (Over -115), already down 2 points from a 41.5 opener. The latest move, from 40.5 to 39.5, came early this morning. The Over is seeing 65% of tickets, but 77% of money is on the Under.

OPENING ODDS UPDATE: Pittsburgh (1-0 SU/0-1 ATS) eked out a 34-32 victory over the New York Jets. The Steelers closed as 3-point road favorites and needed a 60-yard field goal with 2:10 remaining to get the win.

Seattle (0-1 SU and ATS) and San Francisco were in a low-scoring dogfight throughout their Week 1 clash. But the Seahawks gave up a TD with 1:34 left and lost 17-13 as 2.5-point home underdogs.

Pittsburgh opened as 2.5-point home chalk vs. Seattle in The SuperBook's NFL odds Week 2 market. The Steelers then moved out to -3, while the total was steady at 40.5.

Los Angeles Rams vs. Tennessee Titans Odds

• Opening point spread: Rams -5.5
• Opening moneyline: Rams -238/Titans +195
• Opening total: Over/Under 42.5 points scored
• Time: 1 p.m. ET Sunday (CBS)

GAME DAY UPDATE: With 90 minutes until kickoff, Los Angeles is -5.5 (-115) in BetMGM's NFL odds Week 2 market. And last Sunday, the Rams opened -5.5.

In digital spread play (online/mobile) at BetMGM, L.A. is netting 57% of bets/64% of money. Moneyline action is a little stronger on the road favorite, at 63% of bets/78% of dollars.

The total opened at 45.5 and is down to 41.5 (Under -115). The Under is drawing 76% of bets/83% of money.

MIDWEEK UPDATE: DraftKings hasn't budged off L.A. -5.5 all week. Early spread play is all Rams, with ticket count 4/1 and money 3/1-plus.

Likewise, the total is stable at 42.5, though tickets are 2/1 and money beyond 9/1 on the Under so far.

OPENING ODDS UPDATE: Los Angeles (1-0 SU and ATS) had a lackluster Week 1 showing. But Houston was even more lackluster. The Rams won a 14-9 snoozer laying 3 points at home.

Tennessee (0-1 SU/1-1 ATS) put the fear of God into Circa Survivor entrants and others in Survivor pools across the nation. The Titans were 8.5-point pups at Denver and trailed just 13-12 midway through the fourth quarter. But Tennessee then gave up a TD and lost 20-12.

L.A. opened as a 5.5-point favorite vs. Tennessee, with no movement Sunday night.

New England Patriots vs. Miami Dolphins Odds

• Opening point spread: Dolphins -2
• Opening moneyline: Dolphins -122/Patriots +102
• Opening total: Over/Under 44.5 points scored
• Time: 1 p.m. ET Sunday (CBS)

GAME DAY UPDATE: Miami is -2.5 (-105) on BetMGM's NFL Week 2 odds board, after opening -2.5 last Sunday. Digital betting (online/mobile) favors visiting New England, at 61% of bets/80% of money.

The total is at 43.5 (Under -115) from a 45.5 opener. The Over is taking 55% of bets/69% of money.

MIDWEEK UPDATE: The Dolphins opened -1.5 and spent time at pick 'em early in the week on DraftKings' NFL Week 2 odds board. But today, the line advanced to Miami -1.5/-2.5.

That said, New England is netting 62% of early spread bets, while early spread money is dead even. On the moneyline, it's 65% bets/71% money on the short road 'dog Patriots.

OPENING ODDS UPDATE: Miami (0-1 SU and ATS) flopped in a big way in Week 1. Tua Tagovailoa threw two interceptions, and the Dolphins got drilled 33-8 getting 1 point at Indianapolis.

New England (0-1 SU and ATS) held a 10-7 lead at halftime vs. Las Vegas. But the Patriots managed only a field goal in the second half, losing 20-13 as 2.5-point home favorites.

Miami opened and remains -2 at The SuperBook, and the total hasn't moved off 44.5.

Washington Commanders vs. Green Bay Packers Odds

• Opening point spread: Packers -3.5
• Opening moneyline: Packers -170/Commanders +142
• Opening total: Over/Under 47.5 points scored
• Time: 8:15 p.m. ET Thursday (Prime)

Check out our complete Green Bay Packers vs. Washington Commanders preview.

GAME DAY LATE UPDATE: BetMGM is dealing reduced juice tonight, with the line currently Packers -3 (-110)/Commanders +3 (even) in NFL Week 2 odds. Green Bay opened -1.5 and got as high as -3.5, before nudging down to -3 today.

Counter to that move, though, BetMGM needs the road underdog.

"We're going to need the Commanders here. Most of the action today has been on the Packers," BetMGM trading manager Christian Cipollini said. "The Commanders covering at all is our best case. And of course, we want a low-scoring game."

The total opened at 48.5 and was at 48 this morning, but it's now up to 49. And the move up comes despite a whopping $250,000 bet on Under 48. Cipollini said even with that Under bet, BetMGM is rooting for the Under, primarily due to liability on single-game parlays.

GAME DAY EARLY UPDATE: With seven hours until kickoff, the Packers are -3.5 (even) in ESPNBET's NFL odds Week 2 market. On Sunday night, Green Bay opened -3.5.

It's two-way spread play at the moment, with 51% of bets on the Packers/59% of money on the Commanders. Moneyline bettors are leaning more into the home favorite, at 71% of bets/73% of money.

The total opened at 47.5 and is now at 48.5 (Over -120). The Over is netting 63% of bets/60% of dollars.

MIDWEEK UPDATE: Green Bay opened -3 in Borgata Sports' NFL Week 2 odds, and there's been interest in the home chalk ahead of this Thursday night showdown.

"After the way the Packers looked against Detroit, we saw money come in on them, bumping this number to -3.5," Borgata sportsbook director Tom Gable said. "You may see this get back to 3, but it won’t get higher than 3.5.

"Right now, ticket count leans toward Green Bay, by a 3/1 margin. But the money has balanced out."

The total is down a tick, from 48.5 to 48.

OPENING ODDS UPDATE: Green Bay (1-0 SU and ATS) got a quick leg up in the NFC North in Week 1. The Packers were in control throughout against Detroit, winning 27-13 as 1.5-point home favorites. The Pack didn't allow a touchdown until the final minute.

Washington (1-0 SU and ATS) had no problem dispatching the New York Giants 21-6. The Commanders allowed only a pair of field goals, in the second and third quarters, and cashed as 6-point home favorites.

John Murray, vice president at The SuperBook, said his risk room was impressed with Green Bay.

"The lookahead number last week was Packers -3. But we opened Green Bay -3.5," Murray said Sunday night, noting the Packers were already drawing money last week at -3. "After they thumped the Lions today, you have to think the public will likely be on them Thursday night.

"It's a very good Thursday night game this week."

The total is stable at 47.5.

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson