NFL Week 6 Odds: Lines, Spreads, Betting Trends for Every Game

Patrick Everson Sports Betting Expert

21 minute read

2026 NFL Week 6 Odds

NFL Week 6 odds start off with a strong matchup and include a couple contests invovling teams off to surprising starts this season.

Seattle Seahawks vs. Denver Broncos kicks off Week 6 NFL odds. Other notable matchups: Baltimore Ravens vs. Cleveland Browns and Buffalo Bills vs. Las Vegas Raiders.

Here’s everything you need to know about NFL odds Week 6: opening lines, spreads and betting trends for every game, as multiple oddsmakers provide insights on odds and action.

Prediction markets are in the mix, as well, so check out our Polymarket referral code and get in on the action today. Also, check back regularly for updates and use our bet365 bonus code to get the most out of your action.

Updated on 10/12/26

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2026 NFL Odds for Week 6

Seattle Seahawks vs. Denver Broncos Odds

SEA @ DEN Odds

• Full Game
• 1Q
• 1H
• 2Q
• 4Q
• 3Q

• Spread
• Total
• Moneyline

Time	Open	Bet365	BetMGM	DraftKings	Caesars	FanDuel	HardRock	Fanatics	RiversCasino	Consensus
	Open	›	›	›	›	›	›	›	›
109 Seahawks	-2.5 -105	-2.5 -120	-3 -108	-3 -108	-3 -107	-3 -106	-2.5 -125	-3 -110	-3 -107	-3 -108
110 Broncos	+2.5 -115	+2.5 even	+3 -110	+3 -112	+3 -113	+3 -114	+2.5 +105	+3 -110	+3 -114	+3 -112
Matchup
	Open	›	›	›	›	›	›	›	›
109 Seahawks	o43.5 -110	o42.5 -110	o42.5 -110	o42.5 -110	o42.5 -110	o42.5 -110	o42.5 -110	o42.5 -110	o42.5 -112	o42.5 -110
110 Broncos	u43.5 -110	u42.5 -110	u42.5 -108	u42.5 -110	u42.5 -110	u42.5 -110	u42.5 -110	u42.5 -110	u42.5 -109	u42.5 -110
Matchup
	Open	›	›	›	›	›	›	›	›
109 Seahawks	-130	-153	-160	-155	-157	-158	-160	-165	-159	-155
110 Broncos	+110	+128	+135	+130	+132	+134	+135	+135	+132	+130
Matchup

Time	Open	Bet365	BetMGM	DraftKings	Caesars	FanDuel	HardRock	Fanatics	RiversCasino	Consensus
	Open	›	›	›	›	›	›	›	›
109 Seahawks	-2.5 -105	N/A	N/A	-0.5 +124	N/A	-1.5 +136	-0.5 +120	-0.5 +125	N/A	-3 -108
110 Broncos	+2.5 -115	N/A	N/A	+0.5 -148	N/A	+1.5 -166	+0.5 -160	+0.5 -155	N/A	+3 -112
Matchup
	Open	›	›	›	›	›	›	›	›
109 Seahawks	o43.5 -110	N/A	N/A	o7.5 +102	N/A	o7.5 +102	o7.5 even	o7.5 even	N/A	o42.5 -110
110 Broncos	u43.5 -110	N/A	N/A	u7.5 -122	N/A	u7.5 -124	u7.5 -130	u7.5 -135	N/A	u42.5 -110
Matchup
	Open	›	›	›	›	›	›	›	›
109 Seahawks	-130	N/A	N/A	-130	N/A	-124	N/A	-145	N/A	-155
110 Broncos	+110	N/A	N/A	+110	N/A	+102	N/A	+110	N/A	+130
Matchup

Time	Open	Bet365	BetMGM	DraftKings	Caesars	FanDuel	HardRock	Fanatics	RiversCasino	Consensus
	Open	›	›	›	›	›	›	›	›
109 Seahawks	-2.5 -105	N/A	N/A	-1.5 -105	-1.5 -105	-1.5 -100	-1.5 -115	-2.5 -105	N/A	-3 -108
110 Broncos	+2.5 -115	N/A	N/A	+1.5 -115	+1.5 -115	+1.5 -120	+1.5 -115	+2.5 -115	N/A	+3 -112
Matchup
	Open	›	›	›	›	›	›	›	›
109 Seahawks	o43.5 -110	N/A	N/A	o21.5 -105	o21.5 even	o21.5 -105	o21.5 -110	o20.5 -120	N/A	o42.5 -110
110 Broncos	u43.5 -110	N/A	N/A	u21.5 -115	u21.5 -120	u21.5 -115	u21.5 -120	u20.5 -110	N/A	u42.5 -110
Matchup
	Open	›	›	›	›	›	›	›	›
109 Seahawks	-130	N/A	N/A	-142	-145	-140	N/A	-145	N/A	-155
110 Broncos	+110	N/A	N/A	+120	+121	+116	N/A	+120	N/A	+130
Matchup

Time	Open	Bet365	BetMGM	DraftKings	Caesars	FanDuel	HardRock	Fanatics	RiversCasino	Consensus
	Open	›	›	›	›	›	›	›	›
109 Seahawks	-2.5 -105	N/A	N/A	N/A	N/A	-1.5 -100	-0.5 -120	N/A	N/A	-3 -108
110 Broncos	+2.5 -115	N/A	N/A	N/A	N/A	+1.5 -120	+0.5 -110	N/A	N/A	+3 -112
Matchup
	Open	›	›	›	›	›	›	›	›
109 Seahawks	o43.5 -110	N/A	N/A	N/A	N/A	o20.5 -100	o20.5 -110	N/A	N/A	o42.5 -110
110 Broncos	u43.5 -110	N/A	N/A	N/A	N/A	u20.5 -120	u20.5 -120	N/A	N/A	u42.5 -110
Matchup
	Open	›	›	›	›	›	›	›	›
109 Seahawks	-130	N/A	N/A	N/A	N/A	-138	N/A	N/A	N/A	-155
110 Broncos	+110	N/A	N/A	N/A	N/A	+116	N/A	N/A	N/A	+130
Matchup

Time	Open	Bet365	BetMGM	DraftKings	Caesars	FanDuel	HardRock	Fanatics	RiversCasino	Consensus
	Open	›	›	›	›	›	›	›	›
109 Seahawks	-2.5 -105	N/A	N/A	N/A	N/A	-1.5 +112	-0.5 -105	N/A	N/A	-3 -108
110 Broncos	+2.5 -115	N/A	N/A	N/A	N/A	+1.5 -136	+0.5 -125	N/A	N/A	+3 -112
Matchup
	Open	›	›	›	›	›	›	›	›
109 Seahawks	o43.5 -110	N/A	N/A	N/A	N/A	o13.5 +112	o13.5 +110	N/A	N/A	o42.5 -110
110 Broncos	u43.5 -110	N/A	N/A	N/A	N/A	u13.5 -136	u13.5 -145	N/A	N/A	u42.5 -110
Matchup
	Open	›	›	›	›	›	›	›	›
109 Seahawks	-130	N/A	N/A	N/A	N/A	-140	N/A	N/A	N/A	-155
110 Broncos	+110	N/A	N/A	N/A	N/A	+114	N/A	N/A	N/A	+130
Matchup

Time	Open	Bet365	BetMGM	DraftKings	Caesars	FanDuel	HardRock	Fanatics	RiversCasino	Consensus
	Open	›	›	›	›	›	›	›	›
109 Seahawks	-2.5 -105	N/A	N/A	N/A	N/A	-1.5 +126	-0.5 +105	N/A	N/A	-3 -108
110 Broncos	+2.5 -115	N/A	N/A	N/A	N/A	+1.5 -152	+0.5 -135	N/A	N/A	+3 -112
Matchup
	Open	›	›	›	›	›	›	›	›
109 Seahawks	o43.5 -110	N/A	N/A	N/A	N/A	o11.5 -108	o11.5 -115	N/A	N/A	o42.5 -110
110 Broncos	u43.5 -110	N/A	N/A	N/A	N/A	u11.5 -112	u11.5 -115	N/A	N/A	u42.5 -110
Matchup
	Open	›	›	›	›	›	›	›	›
109 Seahawks	-130	N/A	N/A	N/A	N/A	-128	N/A	N/A	N/A	-155
110 Broncos	+110	N/A	N/A	N/A	N/A	+104	N/A	N/A	N/A	+130
Matchup

Time	Open	Bet365	BetMGM	DraftKings	Caesars	FanDuel	HardRock	Fanatics	RiversCasino	Consensus
	Open	›	›	›	›	›	›	›	›
109 Seahawks	-2.5 -105	N/A	N/A	N/A	N/A	-1.5 +124	-0.5 +115	N/A	N/A	-3 -108
110 Broncos	+2.5 -115	N/A	N/A	N/A	N/A	+1.5 -150	+0.5 -150	N/A	N/A	+3 -112
Matchup
	Open	›	›	›	›	›	›	›	›
109 Seahawks	o43.5 -110	N/A	N/A	N/A	N/A	o7.5 -104	o7.5 -105	N/A	N/A	o42.5 -110
110 Broncos	u43.5 -110	N/A	N/A	N/A	N/A	u7.5 -118	u7.5 -125	N/A	N/A	u42.5 -110
Matchup
	Open	›	›	›	›	›	›	›	›
109 Seahawks	-130	N/A	N/A	N/A	N/A	-140	N/A	N/A	N/A	-155
110 Broncos	+110	N/A	N/A	N/A	N/A	+114	N/A	N/A	N/A	+130
Matchup

• Opening point spread: Seahawks -2.5
• Opening moneyline: Seahawks -140/Broncos +115
• Opening total: Over/Under 42 points scored
• Time: 8:15 p.m. ET Thursday (Prime)

OPENING ODDS UPDATE: Defending Super Bowl champion Seattle (3-2 SU/1-3-1 ATS) couldn't quite pass a tough Week 5 test. In a back-and-forth contest, the Seahawks fell short to San Francisco 32-29 as 3-point home favorites, losing on a field goal with 1:56 remaining.

Seattle subsequently got to midfield, then fell 1 yard shot on fourth-and-9, turning the ball over on downs.

Denver (3-2 SU and ATS) once again came from behind to win. The Broncos trailed the Chargers 17-10 through the first six minutes of the fourth quarter. Then Denver scored the game's final 13 points — a touchdown and two field goals — to win 23-17 as 3.5-point road favorites.

Borgata Sports, a BetMGM shop in Atlantic City, opened Seahawks-Broncos at Seattle -2.5 in NFL Week 6 odds.

"Seattle is coming off a tough home loss to the Niners, and now travels to Denver on a short week, but is still favored," Borgata sportsbook director Tom Gable said Sunday night. "There's some early money on the home 'dog here."

Not enough to move the spread, but the total nudged from 42 to 42.5 Sunday night.

Houston Texans vs. Jacksonville Jaguars Odds

HOU @ JAC Odds

• Full Game
• 1H
• 1Q

• Spread
• Total
• Moneyline

Time	Open	Bet365	BetMGM	DraftKings	Caesars	FanDuel	Fanatics	RiversCasino	Consensus
	Open	›	›	›	›	›	›	›
261 Texans	-1.5 -102	+2.5 +102	+2.5 -105	+3 -118	+3 -121	+2.5 -100	+2.5 even	+3 -117	+3 -118
262 Jaguars	+1.5 -118	-2.5 -122	-2.5 -115	-3 -102	-3 +101	-2.5 -122	-2.5 -120	-3 -104	-3 -102
Matchup
	Open	›	›	›	›	›	›	›
261 Texans	o41.5 -110	o43.5 -115	o44 -105	o43.5 -115	o43.5 -110	o43.5 -118	o44 -110	o42.5 -109	o43.5 -115
262 Jaguars	u41.5 -110	u43.5 -105	u44 -112	u43.5 -105	u43.5 -110	u43.5 -104	u44 -110	u42.5 -110	u43.5 -105
Matchup
	Open	›	›	›	›	›	›	›
261 Texans	-115	+130	+125	+124	+129	+130	+125	+130	+124
262 Jaguars	-105	-155	-150	-148	-152	-154	-150	-157	-148
Matchup

Time	Open	Bet365	BetMGM	DraftKings	Caesars	FanDuel	Fanatics	RiversCasino	Consensus
	Open	›	›	›	›	›	›	›
261 Texans	-1.5 -102	N/A	N/A	+1.5 -115	N/A	N/A	+1.5 -115	N/A	+3 -118
262 Jaguars	+1.5 -118	N/A	N/A	-1.5 -105	N/A	N/A	-1.5 -105	N/A	-3 -102
Matchup
	Open	›	›	›	›	›	›	›
261 Texans	o41.5 -110	N/A	N/A	o22.5 -108	N/A	N/A	o20.5 -120	N/A	o43.5 -115
262 Jaguars	u41.5 -110	N/A	N/A	u22.5 -112	N/A	N/A	u20.5 -110	N/A	u43.5 -105
Matchup
	Open	›	›	›	›	›	›	›
261 Texans	-115	N/A	N/A	+120	N/A	N/A	+120	N/A	+124
262 Jaguars	-105	N/A	N/A	-142	N/A	N/A	-145	N/A	-148
Matchup

Time	Open	Bet365	BetMGM	DraftKings	Caesars	FanDuel	Fanatics	RiversCasino	Consensus
	Open	›	›	›	›	›	›	›
261 Texans	-1.5 -102	N/A	N/A	+0.5 -142	N/A	N/A	+0.5 -145	N/A	+3 -118
262 Jaguars	+1.5 -118	N/A	N/A	-0.5 +120	N/A	N/A	-0.5 +120	N/A	-3 -102
Matchup
	Open	›	›	›	›	›	›	›
261 Texans	o41.5 -110	N/A	N/A	o8.5 -110	N/A	N/A	o7.5 -110	N/A	o43.5 -115
262 Jaguars	u41.5 -110	N/A	N/A	u8.5 -110	N/A	N/A	u7.5 -120	N/A	u43.5 -105
Matchup
	Open	›	›	›	›	›	›	›
261 Texans	-115	N/A	N/A	+110	N/A	N/A	+110	N/A	+124
262 Jaguars	-105	N/A	N/A	-130	N/A	N/A	-145	N/A	-148
Matchup

• Opening point spread: Jaguars -2.5
• Opening moneyline: Jaguars -145/Texans +125
• Opening total: Over/Under 42 points scored
• Time: 9:30 a.m. ET Sunday, in London (NFL Network)

OPENING ODDS UPDATE: Jacksonville (4-1 SU/3-2 ATS) closed as a 7.5-point favorite vs. injury-ravaged Philadelphia. Yet it took every second of the game just to win, never mind covering the number.

The Jaguars gave up a Philly field goal with eight seconds left to fall behind 17-16. But Ameer Abdullah returned the ensuing kick 57 yards to the Eagles' 39-yard line, getting tackled with one second left. Cam Little then booted a 57-yard field goal to give Jacksonville a stunning 19-17 victory.

Houston (1-4 SU and ATS) finally found its way to the win column, on the field and at the betting window. The Texans gave up an early field goal at Tennessee, then scored the rest of the points in a 26-3 victory as 6.5-point favorites.

At BetMGM on Sunday night, Texans-Jags opened at Jacksonville -2.5 (-115) in NFL odds Week 6. The spread toggled to Jags -3 (-102) a couple times, then settled at -2.5 (-118).

The total was more on the move, going from 42 to 43.5 and settling at 44 (Under -115).

Baltimore Ravens vs. Cleveland Browns Odds

Ravens @ Browns Betting Odds

• Spread
• Total
• Moneyline

Time	Open	Bet365	BetMGM	DraftKings	Caesars	FanDuel	RiversCasino	Consensus
	Open	›	›	›	›	›	›
267 Ravens	-6.5 -110	-4.5 -105	-4.5 -105	-3.5 -115	-3.5 -115	-4.5 -110	-4.5 -108	-3.5 -115
268 Browns	+6.5 -110	+4.5 -115	+4.5 -112	+3.5 -105	+3.5 -105	+4.5 -110	+4.5 -113	+3.5 -105
Matchup
	Open	›	›	›	›	›	›
267 Ravens	o44.5 -110	o40.5 -112	o41 -110	o40.5 -115	o40.5 -110	o41.5 -105	o41.5 -106	o40.5 -115
268 Browns	u44.5 -110	u40.5 -108	u41 -108	u40.5 -105	u40.5 -110	u41.5 -115	u41.5 -113	u40.5 -105
Matchup
	Open	›	›	›	›	›	›
267 Ravens	-270	-210	-220	-218	-209	-215	-220	-218
268 Browns	+220	+175	+180	+180	+175	+180	+175	+180
Matchup

• Opening point spread: Ravens -4
• Opening moneyline: Ravens -225/Browns +180
• Opening total: Over/Under 41 points scored
• Time: 1 p.m. ET Sunday (FOX)

OPENING ODDS UPDATE: Baltimore (3-1 SU/1-3 ATS) is in the midst of its Week 5 matchup, visiting Atlanta in the Sunday night game. And the Ravens are without QB Lamar Jackson (ankle).

Cleveland (3-2 SU and ATS) saw its unexpected three-game win streak end in Week 5. The Browns failed to find the end zone until the fourth quarter in a 17-12 rock fight of a loss as 2.5-point road underdogs to the Jets.

Baltimore opened as 4-point road chalk in Borgata Sports' NFL odds Week 6, and that number is already on the move Sunday night.

"The Ravens are up to 4.5-point favorites now," Borgata sportsbook director Tom Gable said. "Lamar Jackson remains week-to-week. All of the early money here has been on Baltimore, laying the points."

Early reports suggest Jackson might return to face the Browns. That's something to keep an eye on, as that could further move the number in Baltimore's favor.

Carolina Panthers vs. Philadelphia Eagles Odds

CAR @ PHI Odds

• Full Game
• 1Q
• 1H

• Spread
• Total
• Moneyline

Time	Open	Bet365	BetMGM	DraftKings	Caesars	FanDuel	Fanatics	RiversCasino	Consensus
	Open	›	›	›	›	›	›	›
273 Panthers	+6.5 -110	+1.5 -110	+1.5 -110	+1.5 -110	+1.5 -109	+1.5 -110	+1.5 -110	+1.5 -113	+1.5 -110
274 Eagles	-6.5 -110	-1.5 -110	-1.5 -108	-1.5 -110	-1.5 -109	-1.5 -110	-1.5 -110	-1.5 -108	-1.5 -110
Matchup
	Open	›	›	›	›	›	›	›
273 Panthers	o43.5 -110	o42.5 -108	o42 -110	o42.5 -108	o42.5 -108	o42.5 -112	o42.5 -110	o42.5 -110	o42.5 -108
274 Eagles	u43.5 -110	u42.5 -112	u42 -108	u42.5 -112	u42.5 -112	u42.5 -108	u42.5 -110	u42.5 -110	u42.5 -112
Matchup
	Open	›	›	›	›	›	›	›
273 Panthers	+230	+105	+105	+105	+102	+104	+105	even	+105
274 Eagles	-285	-125	-125	-125	-120	-122	-125	-122	-125
Matchup

Time	Open	Bet365	BetMGM	DraftKings	Caesars	FanDuel	Fanatics	RiversCasino	Consensus
	Open	›	›	›	›	›	›	›
273 Panthers	+6.5 -110	N/A	N/A	+0.5 -155	N/A	N/A	+0.5 -170	N/A	+1.5 -110
274 Eagles	-6.5 -110	N/A	N/A	-0.5 +130	N/A	N/A	-0.5 +135	N/A	-1.5 -110
Matchup
	Open	›	›	›	›	›	›	›
273 Panthers	o43.5 -110	N/A	N/A	o7.5 +110	N/A	N/A	o7.5 even	N/A	o42.5 -108
274 Eagles	u43.5 -110	N/A	N/A	u7.5 -130	N/A	N/A	u7.5 -135	N/A	u42.5 -112
Matchup
	Open	›	›	›	›	›	›	›
273 Panthers	+230	N/A	N/A	-102	N/A	N/A	even	N/A	+105
274 Eagles	-285	N/A	N/A	-118	N/A	N/A	-130	N/A	-125
Matchup

Time	Open	Bet365	BetMGM	DraftKings	Caesars	FanDuel	Fanatics	RiversCasino	Consensus
	Open	›	›	›	›	›	›	›
273 Panthers	+6.5 -110	N/A	N/A	+0.5 -115	N/A	N/A	+1.5 -135	N/A	+1.5 -110
274 Eagles	-6.5 -110	N/A	N/A	-0.5 -105	N/A	N/A	-1.5 +110	N/A	-1.5 -110
Matchup
	Open	›	›	›	›	›	›	›
273 Panthers	o43.5 -110	N/A	N/A	o20.5 -110	N/A	N/A	o20.5 -120	N/A	o42.5 -108
274 Eagles	u43.5 -110	N/A	N/A	u20.5 -110	N/A	N/A	u20.5 -110	N/A	u42.5 -112
Matchup
	Open	›	›	›	›	›	›	›
273 Panthers	+230	N/A	N/A	+102	N/A	N/A	even	N/A	+105
274 Eagles	-285	N/A	N/A	-122	N/A	N/A	-120	N/A	-125
Matchup

• Opening point spread: Eagles -1.5
• Opening moneyline: Eagles -120/Panthers even
• Opening total: Over/Under 43.5 points scored
• Time: 1 p.m. ET Sunday (CBS)

OPENING ODDS UPDATE: Philadelphia (2-3 SU/1-4 ATS) lost for the third straight week, and this time in stunning fashion. The injury-plagued Eagles sufferd a 19-17 setback as 7.5-point favorites vs. Jacksonville in London.

Philly took the lead with eight seconds left on a Jake Elliott 48-yard field goal. But the Eagles allowed Ameer Abdullah to return the ensuing kick 53 yards, to the Philly 39-yard line with one second left. Then came a 57-yard field goal that beat the Eagles.

Carolina (2-2 SU and ATS) was one of the first two teams to get a bye, joining Kansas City in Week 5. That was after the Panthers upset Detroit 32-26 catching 4.5 points in the Week 4 Sunday night game.

BetMGM opened the Eagles -1.5 and briefly went to -1 Sunday night in Week 6 NFL odds, then settled back at -1.5. The total dipped from 43.5 to 42.5/42, then stabilized at 42.5 Sunday night.

Chicago Bears vs. Atlanta Falcons Odds

Bears @ Falcons Betting Odds

• Spread
• Total
• Moneyline

Time	Open	Bet365	BetMGM	DraftKings	Caesars	FanDuel	RiversCasino	Consensus
	Open	›	›	›	›	›	›
269 Bears	-3 -115	-1.5 -110	-2.5 -108	+1.5 -115	+1.5 -114	-2.5 -108	-2.5 -109	+1.5 -115
270 Falcons	+3 -105	+1.5 -110	+2.5 -110	-1.5 -105	-1.5 -105	+2.5 -112	+2.5 -112	-1.5 -105
Matchup
	Open	›	›	›	›	›	›
269 Bears	o47.5 -110	o47.5 -112	o48 -108	o47.5 -110	o47.5 -110	o48.5 -105	o46.5 -110	o47.5 -110
270 Falcons	u47.5 -110	u47.5 -108	u48 -110	u47.5 -110	u47.5 -110	u48.5 -115	u46.5 -109	u47.5 -110
Matchup
	Open	›	›	›	›	›	›
269 Bears	-166	-120	-140	-110	-115	-134	-139	-110
270 Falcons	+140	even	+115	-110	-103	+114	+115	-110
Matchup

• Opening point spread: Bears -1
• Opening moneyline: Bears -120/Falcons even
• Opening total: Over/Under 47.5 points scored
• Time: 1 p.m. ET Sunday (FOX)

OPENING ODDS UPDATE: Atlanta (2-2 SU and ATS) is in the middle of its Week 5 assignment, hosting Baltimore in Sunday Night Football.

After an 0-2 SU and ATS start, the Falcons are running hot behind Bijan Robinson and Brian Robinson. Atlanta put up 70 points across Weeks 3 and 4. In a 45-24 Week 4 rout of New Orleans, Bijan had two touchdowns and Brian three.

Chicago (3-2 SU and ATS) got two wins in a row with backup QBs, but couldn't get a third. Tyson Bagent threw two interceptions and got yanked in the fourth quarter, and the Bears got smoked 31-7 as 1.5-point road favorites vs. Green Bay.

Borgata Sports opened Chicago -1 in NFL Week 6 odds. That number didn't last long Sunday night, largely due to an update on Bears QB Caleb Williams, who's missed three games with a hamstring injury.

"The Bears never appeared to be in the game against Green Bay today," Borgata sportsbook director Tom Gable said. "But we are assuming that Caleb Williams returns here against Atlanta in Week 6, after the comments from Ben Johnson. So we went to Bears -2.5.

"With the way the Falcons have been playing since Michael Penix came back, the Bears will definitely need Williams. There was some opening money on Chicago laying the point."

New York Jets vs. New England Patriots Odds