2025 College Football Odds Week 11: Lines, Spreads, Betting Trends on Biggest Games

Patrick Everson Sports Betting Expert

13 minute read

The College Football Odds Week 11 market doesn't necessarily include a marquee matchup. But there are most certainly key contests that will impact College Football Playoff odds.

Perhaps the most intriguing game in college football Week 11 odds: BYU vs. Texas Tech in the Big 12. Indiana aims to keep rolling, as well, at Penn State.

Here’s everything you need to know about college football odds Week 11: opening lines, spreads and betting trends for the biggest games, as multiple oddsmakers provide insights on Week 11 college football odds and action.

Check back regularly for updates and use our bet365 bonus code to get the most out of your action.

(Feature image: Scott Clause/Imagn Images)

2025 College Football Odds for Week 11

LSU vs. Alabama Odds

• Opening point spread: Alabama -11
• Opening moneyline: Alabama -420/LSU +340
• Opening total: Over/Under 51.5 points scored
• Time: 7:30 p.m. ET Saturday (ABC)

GAME DAY UPDATE: BetMGM has Alabama at -10 (-115) in the college football odds Week 11 market, 90 minutes before kickoff. The Crimson Tide opened -11.5, quickly went to -10.5 Sunday and spent much of the week at -10.

On Friday, 'Bama returned to -10.5, then early this evening again went to -10 and even spent a few minutes at -9.5.

"We're seeing a lot of LSU money at +10.5. Plenty of action from our Louisiana bettors, and sharps really like LSU tonight, too," BetMGM trading manager Seamus Magee said. "As it stands, the book is rooting for 'Bama to cover -10.5.

"Plenty of money will come in between now and kickoff. If LSU covers +10.5, we'd like to see the Tigers win outright, to get some moneyline backers and parlays back. Alabama winning and not covering isn't what we want to see.

MIDWEEK UPDATE: As of 2 p.m. ET Thursday, DraftKings has Alabama at -10 (-105) in its college football Week 11 odds. In fact, earlier Thursday, the line briefly went to 'Bama -9.5. The Crimson Tide opened -11.5 and spent the first half of the week at -10.5.

Alabama is taking 73% of early spread bets, but early spread money is much closer, with 54% on the Tide.

DK's total has been at 49.5 since Monday evening, matching the opener after making a couple trips to 50.5. The Over is attracting 75% of bets/78% of money.

EARLY WEEK UPDATE: Alabama opened as 11.5-point chalk in Borgata Sports' college football odds Week 11 market.

"It's LSU’s first game since firing Brian Kelly," Borgata sportsbook director Tom Gable said. "Bettors typically like to bet on a team that just fired its coach. That was the case in this game, with early money coming in on LSU. 'Bama is down to -10."

OPENING ODDS UPDATE: No. 4 Alabama (7-1 SU/5-3 ATS) got a much-needed week off after facing four straight ranked opponents, and taking down all four (3-1 ATS).

In Week 9, the Crimson Tide narrowly averted their second loss of the season. Trailing South Carolina 22-14 with 10 minutes left, 'Bama rallied for a pair of touchdowns to escape with a 29-22 win as 12.5-point road favorites.

LSU (5-3 SU/3-5 ATS) also had a bye last week, and needed it. The Tigers are on a 1-3 SU and ATS skid that cost Brian Kelly his job. In Week 9, LSU was a 1.5-point home 'dog and got trucked by Texas A&M 49-25, after which Kelly was fired.

Alabama hasn't moved off Circa Sports' -11 opener in the college football odds Week 11 market. But the total dropped from 51.5 to 49.5 in short order Sunday, then settled at 50 after about an hour.

Check out VegasInsider's College Football Week 11 Best Bets!

Navy vs. Notre Dame Odds

• Opening point spread: Notre Dame -26
• Opening moneyline: Notre Dame -3500/Navy +1600
• Opening total: Over/Under 56.5 points scored
• Time: 7:30 p.m. ET Saturday (NBC)

GAME DAY UPDATE: As of 6 p.m. ET, the Fighting Irish are up to 28-point home favorites at BetMGM. That high point was reached Friday night, on a line that opened Notre Dame -25.5, went to -26.5 Tuesday and -27.5 Friday morning.

"Not a ton of action on this one. We'll want to see Navy cover the big number," BetMGM trading manager Seamus Magee said.

The total is at 55.5 (Under -115), where it's stood since Thursday evening, after opening 55.5 and going to 56.5 Tuesday morning.

LATE WEEK UPDATE: On Friday night, Notre Dame is out to -27.5 (-118) in DraftKings Sportsbook's college football Week 11 odds. On Friday morning, the Fighting Irish moved from -26.5 (-112) to -27.5 (-105).

Early in the week, Notre Dame toggled between -24.5/-25.5 a couple times. But the spread has gone nowhere but up since Monday morning. With such a massive number, the Irish are taking a nominal 58% of spread bets/61% of spread money.

The total is at 55.5 (Over -112), after opening 55.5 (Under -120), touching 56.5 (Under -115) Sunday and bottoming out at 54.5 (Over -118) Thursday night. The Over is getting 59% of bets/61% of cash.

EARLY WEEK UPDATE: Notre Dame opened as a hefty 25.5-point home favorite at Borgata Sports. As of 6:30 p.m. ET Tuesday, the Fighting Irish are -26.5.

"With the big spread, we haven’t seen many jump in on the Irish yet. But we have taken some recreational money on Navy," Borgata sportsbook director Tom Gable said.

OPENING ODDS UPDATE: No. 10 Notre Dame (6-2 SU/3-4-1 ATS) lost its first two games, but is now cruising toward a potential CFP bid. In Week 10, the Fighting Irish took care of Boston College 25-10, though they fell miles short of covering a hefty 31.5-point spread.

Navy (7-1 SU/2-6 ATS) just took its first loss of the season. The Midshipmen were 6.5-point pups at North Texas and tumbled 31-17.

Circa Sports opened Notre Dame as 26-point home chalk early Sunday afternoon ET, with no movement so far. The total is stable, as well, at 56.5.

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Wake Forest vs. Virginia Odds

• Opening point spread: Virginia -7.5
• Opening moneyline: Virginia -240/Wake Forest +205
• Opening total: Over/Under 50.5 points scored
• Time: 7 p.m. ET Saturday (ESPN)

GAME DAY UPDATE: An hour before game time, Virginia is -6.5 (-115) at BetMGM. In fact, the only move this week was from the Cavaliers -6.5 flat opener to -6.5 (-115) on Monday.

"The public is fading Virginia tonight. Lots of money pouring in on Wake to cover +6.5 in Charlottesville," BetMGM trading manager Seamus Magee said.

BetMGM's total hasn't moved off 48.5 all week, opening at the flat -110 juice and spending much of the week at the current 48.5 (Under -115). Magee said there's not much of a decision on that market.

LATE WEEK UPDATE: Virginia has toggled between -6.5/-7 at various juice several times this week in DraftKings' college football odds Week 11 market. On Friday night, less than 24 hours before kickoff, the Cavaliers are -6.5 (-115).

Virginia is drawing 70% of spread tickets, but 71% of spread cash is on road 'dog Wake Forest.

DK's total bounced between 48.5/47.5 a few times this week and is now at 48.5 (Under -115). The Over is taking 65% of bets, and 68% of money is on the Under.

EARLY WEEK UPDATE: As of 6:30 p.m. ET Tuesday, Virginia is a stable 6.5-point home favorite in Borgata Sports' college football Week 11 odds.

"Virginia's special teams were a huge issue in the Cal game," Borgata sportsbook director Tom Gable said. "We’ll see if the Cavaliers can clean it up against Wake Forest, as they continue to control their own destiny in the ACC and still have a chance to make the playoffs."

OPENING ODDS UPDATE: No. 14 Virginia (8-1 SU/6-3 ATS) is now atop the ACC, after Georgia Tech's Week 10 upset loss to N.C. State. The Cavaliers did their part, beating California 31-21 as 5.5-point road underdogs.

Virginia is on a 7-0 SU/5-2 ATS roll.

Wake Forest (5-3 SU and ATS) saw its three-game SU and four-game ATS streaks go up in smoke in Week 10. The Demon Deacons got waxed 42-7 catching 12.5 points at Florida State.

Circa opened Wake-Virginia at Cavaliers -7.5 early Sunday afternoon in college football Week 11 odds. Within minutes, the first move went toward the Demon Deacons, with Virginia nudging to -7. The total saw a bigger move, from 50.5 down to 49.

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Texas A&M vs. Missouri Odds

• Opening point spread: Texas A&M -7
• Opening moneyline: Texas A&M -270/Missouri +230
• Opening total: Over/Under 50.5 points scored
• Time: 3:30 p.m. ET Saturday (ABC)

Before you bet, check out VI's Texas A&M vs. Missouri Prediction!

GAME DAY UPDATE: With kickoff 60 minutes out, Texas A&M is -7 (-105) in BetMGM's college football Week 11 odds. In fact, this line has been painted at Aggies -7 since Monday morning, with only a couple juice adjustments, after opening -6 Sunday.

"This is a great looking book for us so far. There's still plenty of time until kickoff, but we've taken solid action both ways, on the spread and the moneyline. There's no real need, including on the total," BetMGM trading manager Seamus Magee said.

That total is at 48.5, where it's stood since Thursday evening, after opening at 49.5 and bottoming out at 47.5 Wednesday morning.

LATE WEEK UPDATE: The Aggies are toggling between -6.5/-7 at DraftKings and are at -7 (-105) as of 2 p.m. ET Thursday. Texas A&M, which opened -6 on Sunday, is netting 75% of bets/66% of money on the spread so far.

DK's total is at 47.5, after opening at 49.5 and spending the early part of the week mostly at 48.5. The Over is landing 81% of early bets/78% of early money.

EARLY WEEK UPDATE: Texas A&M hit Borgata's Week 11 college football odds as 6-point chalk and is already up a point. But there's intrigue in home 'dog Mizzou, as well.

"A&M took some early money, and it’s moved to -7. At 7, though, we are starting to get some buyback on Missouri," Borgata sportsbook director Tom Gable said. "A&M looks to maintain their undefeated season after a bye week.

"Missouri is also coming off a bye week. We last saw the Tigers lose to Vanderbilt, in a game that also saw them lose starting quarterback Beau Pribula. Missouri’s ground game is still formidable, though."

Pribula suffered a dislocated ankle, which could keep him out the rest of the season.

OPENING ODDS UPDATE: No. 3 Texas A&M (8-0 SU/4-4 ATS) resumes its hard charge toward a spot in the SEC championship game and high CFP seed. The Aggies had a bye in Week 10, after thumping LSU 49-25 giving 1.5 points on the road in Week 9.

No. 22 Missouri (6-2 SU/5-3 ATS) can't take another SEC loss, having already fallen to Alabama and Vanderbilt. Like A&M, the Tigers are coming off a bye, following their 17-10 loss catching 3 points at Vandy. Mizzou had a final-seconds Hail Mary that came up 1 yard short.

Circa opened A&M -7 and the line quickly moved to -6 early Sunday afternoon. The total was also on the move right away, from 50.5 down to 49 in college football Week 11 odds.

BYU vs. Texas Tech Odds

• Opening point spread: Texas Tech -10
• Opening moneyline: Texas Tech -385/BYU +315
• Opening total: Over/Under 53.5 points scored
• Time: Noon ET Saturday (ABC)

Before you wager, read up on VegasInsider's BYU vs. Texas Tech Prediction!

GAME DAY UPDATE: With 45 minutes until kickoff, Texas Tech is out to -13.5 at BetMGM, getting a huge shove Friday night/this morning. On Friday night, the Red Raiders went from -10.5 (-115) to -11.5, then this morning climbed to -12.5/-13.5, with -105 juice on both sides.

"A serious move on Texas Tech. We're gonna need BYU to cover, even down to as low as +10.5. It's been one-way traffic on Texas Tech today," BetMGM trading manager Seamus Magee said.

The total is at 50.5 (Under -118) in BetMGM's college football Week 11 odds., having just moved up from a low of 49.5 (Over -115), after opening at 53.5. However, Magee said there's not much of a decision.

LATE WEEK UPDATE: DraftKings Sportsbook has Texas Tech as 10-point home chalk in its college football odds Week 11 market, as of 2 p.m. ET Thursday. That matches the opening number, after toggling early in the week between Red Raiders -10/-10.5 and even briefly touching -9.5.

Opinion is divided in early point-spread action, with 67% of tickets on underdog BYU and 65% of money on Texas Tech.

DraftKings' total has been at 52.5 (Under -115) since Monday afternoon, after opening at 53.5. Sunday and dipping to 52.5 flat within a few hours. The Over is seeing 73% of early bets, but just 53% of early dollars.

EARLY WEEK UPDATE: On Monday night, Borgata Sports has seen no change to its opener of Texas Tech -10.5 in college football Week 11 odds.

"BYU is coming off a bye week, after a very nice victory over Iowa State a couple of weeks ago. It's a tough scheduling spot for the Cougars," Borgata sportsbook director Tom Gable said. "The Red Raiders are coming off a beatdown of Kansas State, in what was an easy cover.

"Now they look to give BYU its first loss in Big 12 play."

The only movement so far is on the total, dipping from 53.5 to 52.5.

OPENING ODDS UPDATE: No. 7 BYU (8-0 SU/6-2 ATS) leads the Big 12 in pursuit of a CFP bid and is coming off a bye week. In Week 9, the Cougars trailed Iowa State 24-10 late in the second quarter, then scored 31 of the final 34 points in a 41-27 victory as 2.5-point road underdogs.

No. 8 Texas Tech (8-1 SU/7-2 ATS) bounced back from a Week 8 loss at Arizona State by posting two wins. In Week 10 at Kansas State, the Red Raiders were 7-point favorites and rolled to a 43-20 victory, putting up 31 second-half points.

Circa Sports, whose opening numbers often take sharp play, set Texas Tech as 10-point home chalk in Week 11 college football odds. Shortly thereafter Sunday afternoon, the Red Raiders advanced to -10.5.

Indiana vs. Penn State Odds

• Opening point spread: Indiana -13
• Opening moneyline: Indiana -680/Penn State +505
• Opening total: Over/Under 47.5 points scored
• Time: Noon ET Saturday (TV TBA)

GAME DAY UPDATE: BetMGM has Indiana as 13.5-point home chalk, having just moved off -14 with 45 minutes until kickoff. That matches the opening number, though the Hoosiers quickly went to -14 Sunday, peaked at -15.5 Monday and spent most of the week at -14.5.

"Penn State +14.5 is what the book will be cheering for today," BetMGM trading manager Seamus Magee said. "There are plenty of shot-takers on Penn State moneyline. But if Penn State upsets Indiana, it will kill a ton of parlays and most likely have a great looking live book."

The total is at 50.5, up from a 49.5 opener and Wednesday's 48.5 low point. But Magee said the total isn't much of a decision.

LATE WEEK UPDATE: Indiana is 14.5-point road chalk in DraftKings' college football Week 11 odds. That's up from the opener of Hoosiers -13.5, but down from the high point of -15.5, reached three times already this week.

Regardless, it's all Indiana early, at 82% of spread tickets/79% of spread money.

DK's total is at 48.5 (Over -115), down from the 49.5 opener. Still, the Over is the play so far, at 88% of tickets/90% of money.

EARLY WEEK UPDATE: This point spread is on the move early in Borgata Sports' college football odds Week 11 market.

"Things don’t get easier for the Nittany Lions as they host Indiana, with the Hoosiers opening as 13.5-point road favorites," Borgata sportsbook director Tom Gable said. "That number didn’t last long, as the Hoosiers have taken money not only at -13.5, but also at -14 and -14.5."

Indiana is up to -15.5 Monday night, while sitting in a position many assumed would be Penn State's spot this late in the season.

"If you looked at this game before the season started, and asked people which of these teams would be ranked No. 2 in the country when they met, you would have found almost unanimously Penn State as the answer.  But the season hasn’t played out that way," Gable said.

Borgata's total is down to 48.5 from a 49.5 opener.

OPENING ODDS UPDATE: No. 2 Indiana (9-0 SU/6-3 ATS) just might find itself atop the first CFP rankings this week, though it'll still trail Ohio State in College Football Playoff odds. In Week 10, the Hoosiers smashed Maryland 55-10 laying 21.5 points on the road.

On the other hand, Penn State (3-5 SU/1-7 ATS) is on a five-game slide, during which coach James Franklin was fired. And the Nittany Lions are tied for the worst ATS record in the nation.

In Week 10, Penn State hung around at Ohio State until halftime, trailing 17-14. But that was it for the Nittany Lions in a 38-14 loss catching 17.5 points.

Indiana opened -13.5 in Circa's college football odds Week 11 market. There was no early movement on the spread Sunday, but the total was off and running, from 47.5 straight to 49, then to 49.5.

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson