College Football Odds Week 2: Charleston Southern vs Clemson Lines, Spreads, Betting Trends
Patrick Everson Sports Betting Expert
| Matchup | Spread | Total | Moneyline |
|---|
College football odds for Week 2 are on the board and receiving plenty of attention as we tackle all the major storylines of the weekend. The Charleston Southern Buccaneers and Clemson Tigers meet at Memorial Stadium in Clemson, South Carolina on Saturday, September 9 at 2:15 p.m. ET on ACC Network.
Here's everything you need to know about the college football odds for the Week 2 game between Charleston Southern and Clemson: the opening lines, spreads, betting trends and more. Check back regularly for updates.
Charleston Southern vs No. 25 Clemson Odds
- Opening point spread: TBA
- Opening moneyline: TBA
- Opening total: TBA
- Time: 2:15 p.m. ET Saturday (ACC Network)
Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 2 Report containing spreads, lines, and trends for every Top 25 matchup.
College Football News
-
COLLEGE-FOOTBALL OCT 12, 20252025 College Football Odds Week 8: Lines, Spreads, Betting Trends on Biggest Games
- COLLEGE-FOOTBALL OCT 13, 2025
College Football Week 8 Best Bets: This Team Has A Statement Win
- COLLEGE-FOOTBALL OCT 9, 2025
NCAA Division I Executives Vote To Remove Ban on College Athletes Betting on Professional Sports
- COLLEGE-FOOTBALL OCT 8, 2025
Penn State and Texas Go Down: How This Affects Their Championship Odds/AP Polling
- COLLEGE-FOOTBALL SEP 2, 2025
College Football’s Most Handsome Coaches
- COLLEGE-FOOTBALL OCT 13, 2025
2025-26 CFP Futures Odds: Ohio State Favorite, Indiana Climbs, Penn State Craters
