NFL Odds Week 3: Lines, Spreads, Betting Trends For All 16 Games

Patrick Everson Sports Betting Expert

12 minute read

2025 NFL Odds Week 3

NFL odds for Week 3 have a handful of noteworthy games. But the last one is by far the most attractive.

Detroit Lions vs. Baltimore Ravens on Monday night highlights odds for NFL Week 3. The week kicks off Thursday with Miami Dolphins vs. Buffalo Bills.

Here’s everything you need to know about the NFL odds Week 3 market: opening lines, spreads and betting trends for every game, as multiple oddsmakers provide insights on NFL Week 3 odds and action. Check back regularly for updates and use our bet365 bonus code to get the most out of your action.

(Feature image: Imagn Images)

NFL Odds for Every Game of NFL Week 3

Miami Dolphins vs. Buffalo Bills Odds

• Opening point spread: Bills -12.5
• Opening moneyline: Bills TBA/Dolphins TBA
• Opening total: Over/Under 49.5 points scored
• Time: 8:15 p.m. ET Thursday (Prime)

OPENING ODDS UPDATE: Buffalo (2-0 SU and ATS) needed none of its Week 1 theatrics to get through Week 2. The Bills jumped out to a 20-0 second-quarter lead vs. the New York Jets and coasted to a 30-10 victory as 5.5-point road favorites.

Miami (0-2 SU and ATS) gave up 33 points for the second straight week, and lost for the second straight week. The Dolphins erased a 12-0 first-quarter deficit, taking the lead multiple times, but lost to New England 33-27 as 2.5-point home favorites.

In last week's lookahead line, The SuperBook had the Bills at -10/-10.5 in NFL odds Week 3. But the game reopened Sunday night at Buffalo -12.5 and went to -13 after a couple hours.

"Buffalo looked great today against a Jets team that wiseguys were lining up to bet all week," SuperBook vice president John Murray said. "Miami’s season is already spiraling. It's tough to back the Dolphins on the road Thursday against this Bills team."

Los Angeles Rams vs. Philadelphia Eagles Odds

• Opening point spread: Eagles -4.5
• Opening moneyline: Eagles TBA/Rams TBA
• Opening total: Over/Under 45.5 points scored
• Time: 1 p.m. ET Sunday (FOX)

OPENING ODDS UPDATE: Philadelphia (2-0 SU/1-1 ATS) didn't post a blowout vs. Kansas City, in a Super Bowl rematch. But the Eagles once again came out on top, winning 20-17 as 1.5-point road favorites.

Los Angeles (2-0 SU and ATS) trailed Tennessee 13-10 at halftime. But the Rams steadily pulled away in the second half, winning 33-19 as 5.5-point road favorites.

Rams-Eagles is a rematch of an NFC Divisional Round playoff game last season. Philly held on for a 28-22 victory in that game, while L.A. covered as a 7.5-point road underdog.

On Sunday night, this line saw an early move at The SuperBook.

"We had this at Eagles -4.5, but took some sharp action on the Rams and moved it down to 4," SuperBook vice president John Murray said. "These could be the two best teams in the NFC, if Stafford can stay healthy. Time will tell.

"And finally, a good matchup in the early window. It only took three weeks."

Cincinnati Bengals vs. Minnesota Vikings Odds

• Opening point spread: Vikings -4.5
• Opening moneyline: Vikings TBA/Bengals TBA
• Opening total: Over/Under 47.5 points scored
• Time: 1 p.m. ET Sunday (CBS)

OPENING ODDS UPDATE: Cincinnati (2-0 SU/1-1 ATS) barely avoided losing its home opener. Trailing 27-24, the Bengals got a touchdown with 18 seconds left to beat Jacksonville 31-27 and cash as 3.5-point home faves.

But the Bengals couldn't avoid losing QB Joe Burrow once again. Burrow exited with a toe injury in the second quarter. He might require surgery that could bench him for up to three months.

That could kill Cincy's season if Jake Browning isn't up to the task. And Browning was shaky Sunday, completing 21 of 32 passes for 241 yards and two TDs, but also throwing three interceptions.

Minnesota (1-1 SU and ATS) could not get its offense going in a home opener vs. Atlanta. J.J. McCarthy threw two interceptions and lost a fumble, and the Vikes finished with four turnovers in a 22-6 loss laying 3.5 points.

The SuperBook opened Minnesota -4.5 in Week 3 NFL odds. Bengals-Vikings came off the board once Falcons-Vikings kicked off. Bengals-Vikes will go back up Monday morning.

"We opened this game Vikings -4.5 after having a lookahead number more like Vikings -1/-1.5. That’s of course due to the Joe Burrow injury," SuperBook VP John Murray said. "Not much to report in terms of betting."

Las Vegas Raiders vs. Washington Commanders Odds

• Opening point spread: Commanders -5.5
• Opening moneyline: Commanders TBA/Raiders TBA
• Opening total: Over/Under 47.5 points scored
• Time: 1 p.m. ET Sunday (FOX)

OPENING ODDS UPDATE: Washington (1-1 SU and ATS) managed just 3 points through three quarters Thursday night at Green Bay. The Commanders picked it up in the fourth quarter, but it wasn't enough in a 27-18 loss catching 3 points.

Las Vegas (1-0 SU and ATS) isn't yet out of Week 2. The Raiders host the L.A. Chargers on Monday night.

The SuperBook's lookahead line on Raiders-Commanders was Washington -6.5. On Sunday night, the matchup reopened at Commanders -5.5, with no early movement.

Green Bay Packers vs. Cleveland Browns Odds

• Opening point spread: Packers -9
• Opening moneyline: Packers TBA
• Opening total: Over/Under 42.5 points scored
• Time: 1 p.m. ET Sunday (FOX)

OPENING ODDS UPDATE: Green Bay (2-0 SU and ATS) is making a statement early, climbing up the Super Bowl odds board in the process. In the Week 2 Thursday nighter, the Packers dispatched Washington 27-18 laying 3 points at home.

Cleveland (0-2 SU/1-1 ATS) was competitive with Cincy in Week 1. Not so much in Week 2 at Baltimore. The Browns fell 41-17 catching 12.5 points.

Green Bay opened as 9-point road chalk in The SuperBook's NFL Week 3 odds. There was no movement Sunday night.

Houston Texans vs. Jacksonville Jaguars Odds

• Opening point spread: Jaguars -2
• Opening moneyline: Jaguars TBA/Texans TBA
• Opening total: Over/Under 43 points scored
• Time: 1 p.m. ET Sunday (CBS)

OPENING ODDS UPDATE: Jacksonville (1-1 SU and ATS) couldn't quite pull off a modest Week 2 road upset. The Jaguars led multiple times at Cincinnati, including 27-24 early in the fourth quarter. But Trevor Lawrence & Co. couldn't hang on, losing 31-24 on a final-minute TD.

Houston (0-1 SU and ATS) still has Week 2 work to do. The Texans host Tampa Bay in the opener of a Monday Night Football doubleheader.

Jacksonville opened -2 in The SuperBook's NFL odds Week 2 market, and adjusted to -1.5 after a couple hours Sunday night.

Pittsburgh Steelers vs. New England Patriots Odds

• Opening point spread: Steelers -1
• Opening moneyline: Steelers TBA/Patriots TBA
• Opening total: Over/Under 44 points scored
• Time: 1 p.m. ET Sunday (CBS)

OPENING ODDS UPDATE: Pittsburgh (1-1 SU/0-2 ATS) saw its turn with Aaron Rodgers start well in a Week 1 win over the Jets. Week 2, not so much. The Steelers led 14-7 at halftime, but gave up 24 second-half points in a 31-17 loss laying 3.5 points at home.

New England (1-1 SU and ATS) rebounded from a Week 1 home loss to Las Vegas. The Patriots waged a back-and-forth battle with Miami, winning 33-27 as 2.5-point road underdogs.

Steelers-Pats opened at Pittsburgh -1 in The SuperBook's NFL Week 3 odds, with no movement Sunday night.

New York Jets vs. Tampa Bay Buccaneers Odds

• Opening point spread: Buccaneers -7
• Opening moneyline: Buccaneers TBA/Jets TBA
• Opening total: Over/Under 44.5 points scored
• Time: 1 p.m. ET Sunday (FOX)

OPENING ODDS UPDATE: New York (0-2 SU/1-1 ATS) couldn't keep pace with Buffalo, falling 30-10 as a 5.5-point home 'dog in Week 2. The Jets trailed 30-3 early in the fourth quarter and didn't find the end zone until the final minutes.

Tampa Bay (1-0 SU and ATS) still has to complete its Week 2 task. The Bucs are at Houston on Monday night.

Still, The SuperBook went ahead and opened the Bucs -7 in Week 3 NFL odds. There's been no movement Sunday night.

Indianapolis Colts vs. Tennessee Titans Odds

• Opening point spread: Colts -3
• Opening moneyline: Colts TBA/Titans TBA
• Opening total: Over/Under 43 points scored
• Time: 1 p.m. ET Sunday (CBS)

OPENING ODDS UPDATE: Indianapolis (2-0 SU and ATS) was perhaps as fortuitous as Dallas in Week 2. Trailing 28-26, the Colts saw Spencer Schrader's 60-yard field goal come up short as time expired.

But the Broncos were flagged for a leverage penalty, moving the ball 15 yards closer. Schrader delivered and Indy won 29-28 as 1.5-point home pups.

Tennessee (0-2 SU/1-1 ATS), behind rookie No. 1 overall draft pick Cam Ward, actually led the L.A. Rams 13-10 at halftime. But the Titans managed just two second-half field goals and lost 33-19 getting 5.5-points at home.

Indy opened as 3-point road chalk at The SuperBook, with no movement as of 10:30 p.m. ET Sunday. The total, however, nudged from 43 to 43.5.

Atlanta Falcons vs. Carolina Panthers Odds

• Opening point spread: Falcons -3.5
• Opening moneyline: Falcons TBA/Panthers TBA
• Opening total: Over/Under 45.5 points scored
• Time: 1 p.m. ET Sunday (FOX)

OPENING ODDS UPDATE: Carolina (0-2 SU/1-1 ATS) rallied from a 27-3 third-quarter deficit at Arizona. But the Panthers came up short 27-22, while covering as 7-point road underdogs.

Atlanta (1-1 SU and ATS) took advantage of four Minnesota turnovers to get its first win. The Falcons notched a 22-6 victory as 3.5-point road underdogs.

Falcons-Panthers opened at Atlanta -3.5 in The SuperBook's NFL odds Week 3 market. Falcons-Panthers was taken off the board once Falcons-Vikes kicked off. Falcons-Panthers will go back up Monday morning.

Denver Broncos vs. Los Angeles Chargers Odds

• Opening point spread: Chargers -2.5
• Opening moneyline: Chargers TBA/Broncos TBA
• Opening total: Over/Under 45.5 points scored
• Time: 4:05 p.m. ET Sunday (CBS)

OPENING ODDS UPDATE: Denver (1-1 SU/0-2 ATS) snatched defeat from the jaws of victory at Indianapolis. The Broncos looked as if they had a 28-26 win when Indy missed a 60-yard field goal as time expired.

However, Denver was dealt a leverage penalty on the play, giving the Colts another shot, which they converted. So the Broncos fell 29-28 laying 1.5 points.

Los Angeles (1-0 SU and ATS) isn't yet out of Week 2. The Chargers travel to Las Vegas for the back end of a Monday Night Football twinbill.

The SuperBook opened Broncos-Chargers at L.A. -2.5, with no movement Sunday night.

New Orleans Saints vs. Seattle Seahawks Odds

• Opening point spread: Seattle -8.5
• Opening moneyline: Seattle TBA/New Orleans TBA
• Opening total: Over/Under 42points scored
• Time: 4:05 p.m. ET Sunday (CBS)

OPENING ODDS UPDATE: Seattle (1-1 SU and ATS) notched a modest road upset in Week 2. The Seahawks trailed Pittsburgh 14-7 at halftime, but woke up and rolled to a 31-17 victory catching 3.5 points.

New Orleans (0-2 SU and ATS) got a big break in Week 2, facing a San Francisco team that was missing Brock Purdy and George Kittle. But the Saints couldn't take advantage, losing 26-21 as 3-point home pups.

Seattle opened as 8.5-point home chalk in The SuperBook's NFL Week 3 odds, with no movement Sunday night.

Dallas Cowboys vs. Chicago Bears Odds

• Opening point spread: Pick 'em
• Opening moneyline: Bears TBA/Cowboys TBA
• Opening total: Over/Under 48.5 points scored
• Time: 4:25 p.m. ET Sunday (FOX)

OPENING ODDS UPDATE: Dallas (1-1 SU and ATS) easily got the most fortuitous win of Week 2, while giving thousands of Circa Survivor entrants a huge sweat.

The Cowboys needed a Brandon Aubrey 64-yard field goal at the end of regulation just to tie the New York Giants at 37 and force overtime. Then OT went to the wire, as well, with Dallas winning 40-37 on Aubrey's final-seconds 46-yard field goal.

But the Pokes didn't cover as 4.5-point home favorites.

Meanwhile, Chicago (0-2 SU and ATS) followed a Monday-night meltdown in Week 1 by getting completely waxed in Week 2. The Bears went to Detroit as 6.5-point underdogs and got smacked 52-21.

Cowboys-Bears saw an adjustment from The SuperBook's lookahead line in NFL Week 3 odds.

"This game was more like Bears -1.5 all last week. But we re-opened it as a pick this afternoon," SuperBook VP John Murray said Sunday night. "Of course, Dallas was extremely fortunate to win today. But there is a downgrade to Chicago based off that defensive performance today in Detroit.

"Dallas should have no problem moving the ball. It also helps when your kicker is good to go, as long as you reach midfield."

Arizona Cardinals vs. San Francisco 49ers Odds

• Opening point spread: 49ers -1
• Opening moneyline: 49ers TBA/Cardinals TBA
• Opening total: Over/Under 43.5 points scored
• Time: 4:25 p.m. ET Sunday (FOX)

OPENING ODDS UPDATE: No Brock Purdy. No George Kittle. No problem for San Francisco (2-0 SU and ATS). The 49ers never trailed at New Orleans, posting a 26-21 victory as 3-point road favorites.

Mac Jones was just fine in place of Purdy, completing 26 of 39 passes for 279 yards and three touchdowns.

Arizona (2-0 SU/1-1 ATS) let almost all of a 27-3 lead slip away against Carolina. But the Cards held on for a 27-22 victory laying 7 points at home.

Purdy's status for Week 3 isn't yet known. The SuperBook opened and remains at 49ers -1 late Sunday night.

Kansas City Chiefs vs. New York Giants Odds

• Opening point spread: Chiefs -5.5
• Opening moneyline: Chiefs TBA/Giants TBA
• Opening total: Over/Under 43 points scored
• Time: 8:20 p.m. ET Sunday (NBC)

OPENING ODDS UPDATE: Kansas City (0-2 SU and ATS) got an almost immediate Super Bowl rematch with Philadelphia. And while the score was closer, the result was the same. The Chiefs lost 20-17 as 1.5-point home 'dogs.

New York (0-2 SU/1-1 ATS) was in position to post the biggest upset of Week 2. The Giants led Dallas 37-34 with 25 seconds left, after a 48-yard TD pass from Russell Wilson to Malik Nabers.

But the G-Men let the Cowboys get in position for a game-tying 64-yard field goal. New York went on to lose on a final-seconds overtime field goal, 40-37 getting 4.5 points on the road.

"We opened Chiefs -5.5, after being up at -6/-6.5 on the lookahead. It's a slight downgrade for Kansas City, which suddenly finds itself at 0-2," SuperBook vice president John Murray said. "I think they’ll be OK. A couple bounces their way today and they would have beaten the Super Bowl champs.

"The book will certainly be big New York Giants fans next Sunday Night."

Detroit Lions vs. Baltimore Ravens Odds

• Opening point spread: Ravens -6.5
• Opening moneyline: Ravens TBA/Lions TBA
• Opening total: Over/Under 52 points scored
• Time: 8:15 p.m. ET Monday (ABC/ESPN)

OPENING ODDS UPDATE: Baltimore (1-1 SU and ATS) rebounded nicely from its stunning Week 1 loss at Buffalo. The Ravens poured it on in a 41-17 victory giving 12.5 points at home vs. Cleveland.

Similarly, Detroit (1-1 SU and ATS) won in even bigger blowout fashion. The Lions trampled Chicago 52-21 as 6.5-point home favorites. Detroit is now 38-12 SU and 36-13-1 ATS in its last 50 games.

The SuperBook opened Baltimore as 6.5-point home chalk vs. Detroit. And at 52, this matchup has the highest total so far this season in the NFL.

"Detroit looked awesome today, crushing the Bears. But we consider Baltimore to be the best team in the league. The Ravens have the highest power rating," SuperBook vice president John Murray said. "It's a great Monday night game. We should do great business on it."

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Completed Games for NFL Week 3

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson