NFL Week 18 Odds: Lines, Spreads, Betting Trends for Every Game

Patrick Everson Sports Betting Expert

13 minute read

2025 NFL Week 18 Odds

NFL Week 18 odds include a full slate of 16 games, including a few with playoff implications. And per usual, Saturday will feature a couple of games, and all the rest will be played Sunday.

There are two for-all-the-marbles matchups in Week 18 NFL odds: Baltimore Ravens vs. Pittsburgh Steelers, and Carolina Panthers vs. Tampa Bay Buccaneers

Here’s everything you need to know about NFL odds Week 18: opening lines, spreads and betting trends for every game, as multiple oddsmakers provide insights on NFL Week 18 odds and action. Check back regularly for updates and use our bet365 bonus code to get the most out of your action.

(Feature image: Peter Casey/Imagn Images)

2025 NFL Odds for Week 18

Baltimore Ravens vs. Pittsburgh Steelers Odds

• Opening point spread: Ravens -3
• Opening moneyline: Steelers TBA/Ravens TBA
• Opening total: Over/Under 42 points scored
• Time: TBA

OPENING ODDS UPDATE: Pittsburgh (9-7 SU/9-6-1 ATS) could've clinched the AFC North and a playoff bid with a Week 16 win at Cleveland. But it wasn't to be. The Steelers mustered just two second-quarter field goals in a 13-6 loss laying 4 points on the road.

That sets up a winner-take-all/loser-goes-home matchup vs. Baltimore in Week 18. The Ravens (8-8 SU/7-9 ATS) faced a must-win Week 17 Saturday night game at Lambeau Field, and got the job done in impressive fashion.

Derrick Henry had 36 carries for a whopping 216 yards and four touchdowns, leading Baltimore to a 41-24 win as 2.5-point underdogs.

The SuperBook opened the Ravens as 3-point favorites in NFL Week 18 odds, with no movement so far Sunday night.

"The AFC North comes down to Week 18. The winner hosts a playoff game, and the loser goes home," SuperBook risk manager Casey Degnon said. "You can't ask for much more from a big-game perspective.

"This should be a great handle game, and I anticipate we'll be rooting for the home 'dog Steelers when they kick off."

Carolina Panthers vs. Tampa Bay Buccaneers Odds

• Opening point spread: Buccaneers -3
• Opening moneyline: Buccaneers TBA/Panthers TBA
• Opening total: Over/Under 43.5 points scored
• Time: TBA

OPENING ODDS UPDATE: Both these teams lost in Week 17, yet will play for the NFC South title in Week 18 with .500 records.

Carolina (8-8 SU/9-7 ATS) has alternated wins and losses in its last 10 games, both SU and ATS. In Week 17, the Panthers managed just 3 points through three quarters and lost to Seattle 27-10 as 6.5-point home underdogs.

Tampa Bay (7-9 SU/5-11 ATS) has been far worse through its last eight games, going 1-7 SU/0-8 ATS. The Bucs closed as 5.5-point Week 17 favorites at Miami and lost 20-17, their fourth consecutive SU setback.

Panthers-Bucs opened at Tampa Bay -3 in The SuperBook's NFL odds Week 18 market, with no early movement Sunday night.

"Same as the AFC North, the NFC South comes down to Week 18," SuperBook risk manager Casy Degnon said. "The Bucs have lost seven of the last eight games, so it's pretty amazing they're still in this position.

"I don't think this will handle as much as the AFC North play-in game. But with such high stakes and a low spread, we will see good public involvement here."

Detroit Lions vs. Chicago Bears Odds

• Opening point spread: Bears -2.5
• Opening moneyline: Bears TBA/Lions TBA
• Opening total: Over/Under 48.5 points scored
• Time: TBA

OPENING ODDS UPDATE: Chicago (11-4 SU/9-5-1 ATS) is in the middle of its Week 17 assignment. The Bears are visiting the 49ers in the Sunday night game.

Detroit (8-8 SU/7-9 ATS) saw its playoff hopes end at Minnesota in Week 17. The Lions had to win to have any chance at postseason play, but fell well short 23-10 giving 7.5 points.

The SuperBook opened at Chicago -2.5 in Week 18 NFL odds Sunday night. But once Bears-Niners kicked off, Lions-Bears came off the board and will go back up Monday morning.

"The Lions are eliminated, but are looking to play spoiler against a division rival," SuperBook risk manager Casey Degnon said. "The Bears have already clinched the NFC North, but this game still matters for seeding.

"I think the Bears will take the majority of the handle here, and we'll be rooting for Dan Campbell and the Lions to end a disappointing season on a high note."

Green Bay Packers vs. Minnesota Vikings Odds

• Opening point spread: Vikings -6.5
• Opening moneyline: Packers TBA/Vikings TBA
• Opening total: Over/Under 37.5 points scored
• Time: TBA

OPENING ODDS UPDATE: Green Bay (9-6-1 SU/6-10 ATS) picked a bad time to go on an 0-3 SU and ATS slide. The Packers, starting Malik Willis in place of concussed Jordan Love, lost to Baltimore 41-24 as 2.5-point home favorites.

Willis had Green Bay in the game, down 27-24 after his 11-yard touchdown run late in the third quarter – his second TD run of the night. But Willis left mid-fourth quarter with a shoulder injury, and the Pack didn't score again.

Minnesota (8-8 SU and ATS) pulled one of the bigger upsets of Week 17, on Christmas Day. The Vikings, catching 7.5 points at home vs. Detroit, rolled to a 23-10 victory, their fourth consecutive SU and ATS win.

Green Bay is in the playoffs, but with nothing to play for in Week 18. So Minnesota opened as 6.5-point home chalk in The SuperBook's NFL Week 18 odds and has already advanced to -7 Sunday night.

"The Vikings open as such a sizeable favorite because the Packers are locked into the seventh seed in the NFC," SuperBook risk manager Casey Degnon said. "We anticipate Green Bay resting some guys and getting healthy for a potential playoff run.

"These games are always hard to predict on how the action will come in. That could depend on just how many guys the Packers end up sitting."

The total is already on the move, too, going from 37.5 to 36.5 Sunday night.

Indianapolis Colts vs. Houston Texans Odds

• Opening point spread: Texans -10
• Opening moneyline: Texans TBA/Colts TBA
• Opening total: Over/Under 39 points scored
• Time: TBA

OPENING ODDS UPDATE: Houston (11-5 SU and ATS) is the hottest team in the NFL at the moment, winning eight in a row (6-2 ATS). In Week 17, the Texans dispatched the L.A. Chargers 20-16 as 1-point road underdogs, clinching a playoff berth in the process.

On the flip side, Indianapolis (8-8 SU and ATS) is on a six-game season-killing slide. The Colts were 4-point home underdogs vs. Jacksonville and jumped out to a 10-0 second-quarter lead, but ultimately lost 23-17.

Houston hit The SuperBook's Week 18 NFL odds as 10-point home chalk, with no movement so far Sunday night.

"The Texans are still playing to win their division, while the Colts started 8-2 before dropping their last six games," SuperBook risk manager Casey Degnon said. "The Colts are expected to go back to Riley Leonard next week, replacing the timeless Philip Rivers.

"I think the book will need the Colts to not only cover, but hopefully pull off the upset come Sunday."

Miami Dolphins vs. New England Patriots Odds

• Opening point spread: Patriots -9.5
• Opening moneyline: Patriots TBA/Dolphins TBA
• Opening total: Over/Under 45.5 points scored
• Time: TBA

OPENING ODDS UPDATE: New England (13-3 SU/11-5 ATS) still has a shot at the AFC's No. 1 seed. In Week 17, the Patriots did what was expected as 13-point road favorites vs. the Jets, rolling to a 42-10 victory.

Miami (7-9 SU/8-8 ATS) got its first win behind Quinn Ewers, in the rookie QB's second start. The Dolphins held off Tampa Bay 20-17 catching 5.5 points at home.

The SuperBook opened the Patriots -9.5 and advanced to -10 in short order Sunday night.

Washington Commanders vs. Philadelphia Eagles Odds

• Opening point spread: Eagles -10.5
• Opening moneyline: Eagles TBA/Commanders TBA
• Opening total: Over/Under 42.5 points scored
• Time: TBA

OPENING ODDS UPDATE: Philadelphia (11-5 SU/10-6 ATS) didn't put up many points in Week 17. But it was enough. The Eagles knocked off Buffalo 13-12 as 3-point underdogs, denying a 2-point attempt in the final seconds to seal the win.

Philly has followed a three-game SU and ATS slide by winning and covering in its last three games.

Washington (4-12 SU/6-10 ATS) didn't have quite enough in Week 17, behind third-string QB Josh Johnson. The Commanders closed as 8.5-point home 'dogs and rallied from a 21-3 second-quarter deficit, but lost to Dallas 30-23.

Commanders-Eagles opened at Philadelphia -10.5 and dipped to -10 Sunday night in The SuperBook's NFL Week 18 odds.

New York Jets vs. Buffalo Bills Odds

• Opening point spread: Bills -14.5
• Opening moneyline: Bills TBA/Jets TBA
• Opening total: Over/Under 42.5 points scored
• Time: TBA

OPENING ODDS UPDATE: Buffalo (11-5 SU/7-9 ATS) still had a chance to win the AFC East, but first and foremost needed a Week 17 win at home. The Bills didn't get it, with a subpar offensive effort in a 13-12 loss to Philadelphia giving 3 points at home.

Josh Allen & Co. rallied from a 13-0 fourth-quarter deficit. But the Bills missed a PAT on their first touchdown, then unsuccessfully went for the 2-point conversion and the win after their second TD, in the game's final seconds.

New York (3-13 SU/5-11 ATS) remains in contention for the No. 1 pick in the NFL Draft. In Week 17, the Jets got trucked by New England 42-10 getting 13 points at home. New York hits Week 18 on an 0-4 SU and ATS slide.

The Jets-Bills line is heavily on the move Sunday night. Buffalo opened -14.5 in The SuperBook's NFL odds Week 18 market and plunged to -12.5 within 20 minutes, with stops at -14/-13.5/-13. Within an hour, the Bills stood at -11.5.

Part of the calculus: With the loss to Philly, Buffalo can no longer win the AFC East and will be a Wild Card team regardless of what happens next weekend.

The total is also a moving target, sitting at 40.5 after opening at 42.5 and making stops at 41.5 and 41.

Cleveland Browns vs. Cincinnati Bengals Odds

• Opening point spread: Bengals -7.5
• Opening moneyline: Bengals TBA/Browns TBA
• Opening total: Over/Under 44 points scored
• Time: TBA

OPENING ODDS UPDATE: Cincinnati (6-10 SU/8-8 ATS) is semi-quietly on a 5-1 ATS surge over its last six games. In Week 17, the Bengals punched out Arizona 37-14 as 7-point home favorites.

Cleveland (4-12 SU/7-9 ATS) made Week 18 much tougher for Pittsburgh, by way of a Week 17 upset win. The Browns were 4-point home 'dogs and held the Steelers to just two second-quarter field goals in a 13-6 victory.

The SuperBook opened the Bengals as 7.5-point home favorites in the NFL odds Week 18 market, with no movement Sunday night. However, the total got an early nudge from 44 to 44.5.

Dallas Cowboys vs. New York Giants Odds

• Opening point spread: Cowboys -5.5
• Opening moneyline: Cowboys TBA/Giants TBA
• Opening total: Over/Under 52 points scored
• Time: TBA

OPENING ODDS UPDATE: Dallas (7-8-1 SU/7-9 ATS) halted a season-killing 0-3 SU and ATS skid in Week 17. The Cowboys blew much of a 21-3 second-quarter lead at Washington, but held on for a 30-23 victory while failing to cash as 8.5-point faves.

New York (3-13 SU/8-8 ATS) didn't let a chance at getting the No. 1 pick interfere with its play in Week 17. The Giants dumped Las Vegas 34-10 laying 3 points on the road to end a nine-game losing streak.

Cowboys-Giants opened at Dallas -5.5 in The SuperBook's Week 18 NFL odds, with no movement Sunday night. The total inched from 52 to 51.5.

Tennessee Titans vs. Jacksonville Jaguars Odds

• Opening point spread: Jaguars -11
• Opening moneyline: Jaguars TBA/Titans TBA
• Opening total: Over/Under 45.5 points scored
• Time: TBA

OPENING ODDS UPDATE: Jacksonville (12-4 SU and ATS) is almost as hot as AFC South rival Houston, and has the inside track to the division title. In Week 17, the Jaguars trailed Indy 10-0 early in the second quarter, but rallied to turn it into a back-and-forth game, winning 23-17.

The Jags are on a 7-0 SU and ATS spree.

Tennessee (3-13 SU/7-9 ATS) jumped out to a 13-0 lead at home vs. New Orleans. But the Titans couldn't make it hold up, losing 34-26 as 1-point home pups.

Jacksonville still has a shot at the No. 1 seed and is trying to hold off Houston for the division title. As such, The SuperBook opened the Jags as 11-point home favorites in NFL Week 18 odds, with no movement so far Sunday night.

New Orleans Saints vs. Atlanta Falcons Odds

• Opening point spread: Falcons -2.5
• Opening moneyline: Falcons TBA/Saints TBA
• Opening total: Over/Under 43.5 points scored
• Time: TBA

OPENING ODDS UPDATE: Atlanta (6-9 SU and ATS) still has Week 16 work to do. The Falcons host the Super Bowl odds favorite Los Angeles Rams in the Monday night game.

New Orleans (6-10 SU/8-8 ATS), behind rookie QB Tyler Shough, has won four in row SU and five in a row ATS. In Week 17, the Saints were in a 13-0 second-quarter hole, but rallied for a 34-26 victory laying 1 point on the road.

The SuperBook opened the Falcons as 2.5-point home favorites, with no early movement Sunday night.

Los Angeles Chargers vs. Denver Broncos Odds

• Opening point spread: Broncos -5.5
• Opening moneyline: Broncos TBA/Chargers TBA
• Opening total: Over/Under 41.5 points scored
• Time: TBA

OPENING ODDS UPDATE: Denver (13-3 SU/6-10 ATS) continues to win one-score games while consistently failing to cover the spread. In Week 17, facing Kansas City third-string QB Chris Oladokun, the Broncos were 13.5-point favorites and eked out a 20-13 victory.

Denver won on an R.J. Harvey 1-yard TD catch with 1:45 remaining. The Broncos are 1-4 ATS in their last five games.

Los Angeles (11-5 SU/9-7 ATS) had a chance to catch Denver for the AFC West title, then squandered that opportunity in Week 17. The Chargers rallied from a 17-3 third-quarter deficit, but couldn't surpass Houston in a 20-16 loss giving 1 point at home.

Chargers-Broncos is on the move early in The SuperBook's NFL Week 18 odds. Denver opened -5.5 and already shot to -8.5, on the chance that Los Angeles rests players, with no chance to move from Wild Card status.

Due to the uncertainty of who will/won't play, The SuperBook took Chargers-Broncos off the board late Sunday evening.

"This is one of the few games that has seen line movement," SuperBook risk manager Casey Degnon said. "We're just trying to stay ahead of the market, as the Broncos are looking to secure a bye week and home field throughout the AFC playoffs.

"The Chargers clinched a playoff spot, but seeding is still up in the air. The line shot up because the Chargers are banged up. We wouldn't be shocked if they sit some guys – Justin Herbert is dealing with some injuries – to try and get healthy for the postseason."

Seattle Seahawks vs. San Francisco 49ers Odds

• Opening point spread: Pick
• Opening moneyline: 49ers TBA/Seahawks TBA
• Opening total: Over/Under 48.5 points scored
• Time: TBA

OPENING ODDS UPDATE: Seattle (13-3 SU/12-4 ATS) kept its hold on the NFC's No. 1 seed in Week 17. The Seahawks had little trouble with Carolina in a 27-10 victory laying 6.5 points on the road. Seattle has won six in a row and is 10-1 SU/8-3 ATS in its last 11 games.

San Francisco (11-4 SU and ATS) is right now in the middle of a big matchup vs. Chicago in the Week 17 Sunday night game.

The SuperBook opened Seahawks-Niners at pick 'em. Once Bears-49ers kicked off, Seahawks-49ers was taken off the board, and it will go back up Monday morning.

"This could be for the division as well as No. 1 seed in the NFC," SuperBook risk manager Casey Degnon said. It's another game that will have really good handle.

"This will probably get flexed into prime time Sunday night, and should see good two-way action all the way up until kickoff."

Arizona Cardinals vs. Los Angeles Rams Odds

• Opening point spread: Rams -14.5
• Opening moneyline: Rams TBA/Cardinals TBA
• Opening total: Over/Under 51.5 points scored
• Time: TBA

OPENING ODDS UPDATE: Los Angeles (11-4 SU/10-5 ATS) still has a Week 17 assignment to complete. The Rams are at Atlanta in the Monday night game.

Arizona (6-10 SU and ATS) saw its modest 2-0 SU and ATS upswing end in Week 17. The Cardinals went to Cincinnati as 7-point road 'dogs and got smoked 37-14.

In Week 18 NFL odds, The SuperBook opened the Rams -14.5 and moved to -14 within 20 minutes. The total moved in a similar time frame, from 51.5 to 50.5.

Kansas City Chiefs vs. Las Vegas Raiders Odds

• Opening point spread: Chiefs -4
• Opening moneyline: Chiefs TBA/Raiders TBA
• Opening total: Over/Under 35.5 points scored
• Time: TBA

OPENING ODDS UPDATE: Kansas City (6-10 SU and ATS) was in it all the way against Denver, despite being 13.5-point home underdogs behind third-string QB Chris Oladokun. The Chiefs lost 20-13, giving up the deciding touchdown with just 1:45 remaining.

Las Vegas (2-14 SU/6-10 ATS) is now the clubhouse leader for the No. 1 pick in the NFL Draft, thanks to a 10-game losing streak. In Week 17, the Raiders were 3-point home 'dogs and got drilled 34-10 by the fellow bottom-feeder Giants.

Neither team has anything but pride to play for, and apparently that's enough for Chiefs backers. Kansas City opened -4 in The SuperBook's NFL Week 18 odds, quickly moved to -4.5, then jumped straight to -6.5. The line then steadied Sunday night at K.C. -6.

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson