College Football Odds Week 3: Alabama vs USF Lines, Spreads, Betting Trends
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College football odds for Week 3 are on the board and receiving plenty of attention as we tackle all the major storylines of the weekend. The Alabama Crimson Tide and South Florida Bulls meet at Raymond James Stadium in Tampa on Saturday, September 16 at 3:30 p.m. ET on ABC.
Here's everything you need to know about the college football odds for the Week 3 game between Alabama vs South Florida: the opening lines, spreads, betting trends and more. Check back regularly for updates.
Alabama vs South Florida Odds

- Opening point spread: Alabama -31
- Opening moneyline: Alabama -10000/South Florida +2000
- Opening total: Over/Under 61.5 points scored
- Time: 3:30 p.m. ET Saturday (ABC)
UPDATE 3:30 P.M. ET FRIDAY: The Crimson Tide toggled between -31.5 and -32.5 throughout the week at BetMGM, and they're currently -32.5. Ticket count is 5/1-plus and money beyond 9/1 on Alabama to strongly bounce back from its home loss to Texas.
Save for a couple of juice adjustments, the total is painted to 61.5 at BetMGM. Early tickets are running 2/1 and money 9/1-plus on the Under.
UPDATE 1 P.M. ET MONDAY: Alabama (1-1 SU and ATS) is in a rare bounce-back spot, after suffering an upset home loss to Texas in Week 2. The Crimson Tide couldn't keep pace with the Longhorns, losing 34-24 as 7-point home favorites.
South Florida (1-1 SU/0-2 ATS) topped FCS opponent Florida A&M 38-24 in Week 2. But the Bulls failed to cover the 19.5-point spread.
'Bama is already up a notch to 31.5 in TwinSpires Sportsbook's college football Week 3 odds market. Early ticket count is 3/1 and early money almost 5/1 on the Tide.
"It's all 'Bama, with folks expecting a bounce-back in a big way," Lucas said.
The total is also up a half-point to 62, with 66% of tickets/61% of money on the Over.
Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 3 Report containing spreads, lines, and trends for every Top 25 matchup.
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