Kentucky vs. Tennessee Prediction: Tennessee’s Defense is Too Tough to Handle

Kentucky vs. Tennessee Prediction: Tennessee’s Defense is Too Tough to Handle

Updated on 11/6/26

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The Kentucky Wildcats will take on the Tennessee Volunteers in this week's college football action. Kickoff is set for 6:15 p.m. EST at Neyland Stadium in Knoxville, TN. The game will be broadcast live on ESPN. Here's everything you need to know about Kentucky vs. Tennessee odds, the latest college football spreads, college football over/unders and more.

UK @ TENN Odds

The Tennessee Volunteers opened as a -6.5 point favorite over Kentucky. The total is set at over/under 49.5 total points scored by both teams combined.

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Updated on 11/6/26

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Kentucky vs. Tennessee Prediction

Tennessee's defense is the unit to look out for here. They rank 10th in EPA/pass allowed and 9th in late-down success rate allowed. It is going to be a tall task for Kentucky to move the ball down the field on this defense.

Tennessee has a strong rush offense, which is where Kentucky's biggest weakness is on defense. Tennessee ranks 5th in EPA/rush, whereas Kentucky ranks 64th in EPA/rush allowed. Tennessee should get it done on the ground and open up the passing game, all while Tennessee's defense shuts down the Kentucky offense.

Kentucky vs. Tennessee Prediction: Tennessee Volunteers -6.5 (-110)

(Pick from Dylan Wilkerson)

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