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Featured Last Updated Nov 6 2026, 11:13 AM

Oregon vs. Ohio State Prediction: Both Offenses Will Struggle

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
14 minute read
Oregon vs. Ohio State Prediction: Both Offenses Will Struggle

Updated on 11/6/26

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The Oregon Ducks will take on the Ohio State Buckeyes in this week's college football action. Kickoff is set for 3:30 p.m. EST at Ohio Stadium in Columbus, OH. The game will be broadcast live on CBS. Here's everything you need to know about Oregon vs. Ohio State odds, the latest college football spreads, college football over/unders and more.

ORE @ OSU Odds

  • Full Game
  • 1H
  • 1Q
  • 3Q
  • 4Q
  • 2Q
  • Spread
  • Total
  • Moneyline
Oregon Ducks 385 Oregon
+6 -110 +4.5 -115 + +4.5 -115 + +4.5 -115 + +4.5 -117 + +4.5 -115 + +4.5 -120 + +4.5 -108 + +7.5 -110  
Ohio State Buckeyes 386 Ohio State
-6 -110 -4.5 -105 + -4.5 -102 + -4.5 -105 + -4.5 -105 + -4.5 -105 + -4.5 -110 + -4.5 -104 + -7.5 -110  
Oregon Ducks 385 Oregon
o52.5 -110 o23.5 -107 + o23.5 -105 + o23.5 -105 + o23.5 -115 + o23.5 -110 + o23.5 -115 + o23.5 -104 + o45.5 -110  
Ohio State Buckeyes 386 Ohio State
u52.5 -110 u23.5 -113 + u23.5 -115 + u23.5 -115 + u23.5 -107 + u23.5 -110 + u23.5 -115 + u23.5 -108 + u45.5 -110  
Oregon Ducks 385 Oregon
+195 N/A N/A N/A N/A N/A N/A +257 + +245  
Ohio State Buckeyes 386 Ohio State
-238 N/A N/A N/A N/A N/A N/A +1011 + -305  
Oregon Ducks 385 Oregon
+6 -110 +0.5 -125 + +0.5 -118 + +0.5 -115 + N/A +1.5 -112 + +0.5 -120 + +2.5 -113 + +7.5 -110  
Ohio State Buckeyes 386 Ohio State
-6 -110 -0.5 -105 + -0.5 -110 + -0.5 -115 + N/A -1.5 -108 + -0.5 -110 + -2.5 -100 + -7.5 -110  
Oregon Ducks 385 Oregon
o52.5 -110 o9.5 -120 + o9.5 -130 + o9.5 -115 + N/A o9.5 -126 + o10.5 +135 + o7.5 -117 + o45.5 -110  
Ohio State Buckeyes 386 Ohio State
u52.5 -110 u9.5 -110 + u9.5 -102 + u9.5 -115 + N/A u9.5 +104 + u10.5 -185 + u7.5 +113 + u45.5 -110  
Oregon Ducks 385 Oregon
+195 N/A N/A N/A N/A N/A N/A +233 + +245  
Ohio State Buckeyes 386 Ohio State
-238 N/A N/A N/A N/A N/A N/A -108 + -305  
Oregon Ducks 385 Oregon
+6 -110 N/A N/A +0.5 -115 + N/A +1.5 -116 + N/A +2.5 -133 + +7.5 -110  
Ohio State Buckeyes 386 Ohio State
-6 -110 N/A N/A -0.5 -115 + N/A -1.5 -106 + N/A -2.5 -117 + -7.5 -110  
Oregon Ducks 385 Oregon
o52.5 -110 o9.5 -135 + N/A o9.5 -130 + N/A o9.5 -126 + N/A o7.5 -186 + o45.5 -110  
Ohio State Buckeyes 386 Ohio State
u52.5 -110 u9.5 -105 + N/A u9.5 even + N/A u9.5 +102 + N/A u7.5 -133 + u45.5 -110  
Oregon Ducks 385 Oregon
+195 N/A N/A N/A N/A N/A N/A +212 + +245  
Ohio State Buckeyes 386 Ohio State
-238 N/A N/A N/A N/A N/A N/A -113 + -305  
Oregon Ducks 385 Oregon
+6 -110 +1.5 -125 + N/A +1.5 -115 + N/A +1.5 -110 + N/A +1.5 -117 + +7.5 -110  
Ohio State Buckeyes 386 Ohio State
-6 -110 -1.5 -115 + N/A -1.5 -115 + N/A -1.5 -110 + N/A -1.5 -108 + -7.5 -110  
Oregon Ducks 385 Oregon
o52.5 -110 o12.5 -115 + N/A o12.5 -125 + N/A o10.5 -112 + N/A o12.5 -117 + o45.5 -110  
Ohio State Buckeyes 386 Ohio State
u52.5 -110 u12.5 -125 + N/A u12.5 -105 + N/A u10.5 -108 + N/A u12.5 -127 + u45.5 -110  
Oregon Ducks 385 Oregon
+195 N/A N/A N/A N/A N/A N/A +400 + +245  
Ohio State Buckeyes 386 Ohio State
-238 N/A N/A N/A N/A N/A N/A -104 + -305  
Oregon Ducks 385 Oregon
+6 -110 N/A N/A +3.5 -135 + N/A +2.5 +108 + N/A +2.5 -113 + +7.5 -110  
Ohio State Buckeyes 386 Ohio State
-6 -110 N/A N/A -3.5 +105 + N/A -2.5 -130 + N/A -2.5 -127 + -7.5 -110  
Oregon Ducks 385 Oregon
o52.5 -110 o13.5 -115 + N/A o13.5 -110 + N/A o13.5 -108 + N/A o13.5 -113 + o45.5 -110  
Ohio State Buckeyes 386 Ohio State
u52.5 -110 u13.5 -125 + N/A u13.5 -120 + N/A u13.5 -112 + N/A u13.5 -113 + u45.5 -110  
Oregon Ducks 385 Oregon
+195 N/A N/A N/A N/A N/A N/A +212 + +245  
Ohio State Buckeyes 386 Ohio State
-238 N/A N/A N/A N/A N/A N/A +488 + -305  
Oregon Ducks 385 Oregon
+6 -110 N/A N/A +3.5 -105 + N/A N/A N/A +3.5 -127 + +7.5 -110  
Ohio State Buckeyes 386 Ohio State
-6 -110 N/A N/A -3.5 -115 + N/A N/A N/A -3.5 -138 + -7.5 -110  
Oregon Ducks 385 Oregon
o52.5 -110 N/A N/A o22.5 -108 + N/A N/A N/A o23.5 -138 + o45.5 -110  
Ohio State Buckeyes 386 Ohio State
u52.5 -110 N/A N/A u22.5 -112 + N/A N/A N/A u23.5 -194 + u45.5 -110  
Oregon Ducks 385 Oregon
+195 N/A N/A N/A N/A N/A N/A +900 + +245  
Ohio State Buckeyes 386 Ohio State
-238 N/A N/A N/A N/A N/A N/A -170 + -305  

The Ohio State Buckeyes opened as a -7 point favorite over Oregon. The total is set at over/under 45.5 total points scored by both teams combined.

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Updated on 11/6/26

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Oregon vs. Ohio State Prediction

Neither of these teams have played fast, and neither of these teams are explosive, so this makes for a low-scoring affair.

Last week, we saw the USC defense led by Lincoln Riley keep this Ohio State team to 18 points. I can only imagine what the Oregon defense is going to be able to keep Luke Fahey from doing.

Both teams have played at a relatively slow pace given their history, with OSU running 74 offensive snaps per game and Oregon running 73. Both teams are in the 75th percentile or better for overall success rate allowed, which tells me these teams are going to struggle to get any offense going.

Oregon vs. Ohio State Prediction: Oregon Ducks @ Ohio State Buckeyes u46.5 (-128)

(Pick from Dylan Wilkerson)

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Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
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