Michigan vs. Iowa Prediction: Low Scoring Big-Ten Affair

Dylan Wilkerson Sports Betting Expert

14 minute read

Updated on 9/22/26

Polymarket

Deposit $10, Get a $50 Trading Bonus!

Bonus Code

INSIDER

Claim $50

18+ Only. Restrictions and eligibility requirements apply. Not available in all jurisdictions. Trading is risky. 100% loss can occur. See polymarket.com/tos for more information. The Polymarket US App serves as an independent software provider and affiliate of Polymarket US and Polymarket Clearing, the CFTC-regulated exchange and clearing organization.

The Iowa Hawkeyes will take on the Michigan Wolverines in this week's college football action. Kickoff is set for 3:30p.m. EST at Michigan Stadium in Ann Arbor, MI. The game will be broadcast live onCBS. Here's everything you need to know about Iowa vs. Michigan odds, the latest college football spreads, college football over/unders and more.

Iowa @ Michigan Betting Odds

• Spread
• Total
• Moneyline

Time	Open	Bet365	BetMGM	DraftKings	Caesars	FanDuel	Fanatics	RiversCasino	Consensus
	Open	›	›	›	›	›	›	›
329 Iowa	+4.5 -110	+5.5 -110	+5.5 -108	+5.5 -110	+5.5 -113	+5.5 -110	+5.5 -110	+5.5 -112	+5.5 -110
330 Michigan	-4.5 -110	-5.5 -110	-5.5 -110	-5.5 -110	-5.5 -107	-5.5 -110	-5.5 -110	-5.5 -112	-5.5 -110
Matchup
	Open	›	›	›	›	›	›	›
329 Iowa	o39.5 -112	o38.5 -110	o38.5 -110	o38.5 -112	o38.5 -110	o38.5 -110	o38.5 -110	o39 -109	o38.5 -112
330 Michigan	u39.5 -108	u38.5 -110	u38.5 -108	u38.5 -108	u38.5 -110	u38.5 -110	u38.5 -110	u39 -113	u38.5 -108
Matchup
	Open	›	›	›	›	›	›	›
329 Iowa	+160	+180	+180	+180	+180	+172	+180	+180	+180
330 Michigan	-192	-220	-220	-218	-218	-210	-220	-230	-218
Matchup

The Michigan Wolverines opened as a -5.5 point favorite over Iowa. The total is set at over/under 38.5 total points scored by both teams combined.

Be sure to check out the latest college football odds and stay up to date on the latest sportsbook promos, including the Polymarket promo code!

Updated on 9/22/26

bet365

Bet $10, Get $200 in Bonus Bets Win or Lose!

Bonus Code

VIBONUS

Claim $200

Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET. Must be 21+ and physically present where bet365 operates. Please gamble responsibly. New customers only. Place qualifying bets of $10 or more to get $200 in Bonus Bets. Deposit required. Bonus bets are non-withdrawable and expire 7 days after receipt. Bonus bet wager excluded from returns. Time limits, min. Odds, and T&Cs apply. This code is used for marketing and tracking purposes only. Void where prohibited. Not eligible in IL, IN, TN, & WV.

Iowa vs. Michigan Prediction

In a pass-heavy college football world, these two teams prefer to hit the ground running. Literally. 56.9% of Michigan's offensive play calls have been runs, and 50.7% of Iowa's offensive play calls have been runs.

This should lead us to a low-scoring affair where the clock is always running and the total score is minuscule. These teams ranks 11th and 18th in overall defense, and both quarterbacks lack the ability to explode through the air. This will be a classic, low-scoring, Big Ten matchup.

Iowa vs. Michigan Prediction: Iowa vs. Michigan Under 38.5

(Pick from Dylan Wilkerson)

Looking for more college football predictions? Check out our free college football picks and our premium subscription for the best picks!

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson