Michigan vs. Iowa Prediction: Low Scoring Big-Ten Affair
Updated on 10/12/26

The Iowa Hawkeyes will take on the Michigan Wolverines in this week's college football action. Kickoff is set for 3:30p.m. EST at Michigan Stadium in Ann Arbor, MI. The game will be broadcast live onCBS. Here's everything you need to know about Iowa vs. Michigan odds, the latest college football spreads, college football over/unders and more.
Iowa @ Michigan Betting Odds
| Time | Open | Bet365 | BetMGM | DraftKings | Caesars | FanDuel | Fanatics | RiversCasino | Consensus | |
|---|---|---|---|---|---|---|---|---|---|---|
| Final | Open | | | | | | | | | |
| | +4.5 -110 | +3.5 -105 | +4.5 -108 | +4.5 -110 | +4.5 -113 | +5.5 -112 | +5 -110 | +5.5 -112 | +4.5 -110 | |
| | -4.5 -110 | -3.5 -115 | -4.5 -110 | -4.5 -110 | -4.5 -115 | -5.5 -108 | -5 -110 | -5.5 -112 | -4.5 -110 | |
| Final | Open | | | | | | | | | |
| | o39.5 -112 | o40.5 -105 | o40.5 -105 | o39.5 -115 | o39.5 -110 | o40.5 -106 | o40 -110 | o39.5 -110 | o39.5 -115 | |
| | u39.5 -108 | u40.5 -115 | u40.5 -112 | u39.5 -105 | u39.5 -110 | u40.5 -114 | u40 -110 | u39.5 -113 | u39.5 -105 | |
| Final | Open | | | | | | | | | |
| | +160 | +155 | +170 | +170 | +158 | +162 | +165 | +170 | +170 | |
| | -192 | -185 | -210 | -205 | -205 | -196 | -200 | -215 | -205 | |
The Michigan Wolverines opened as a -5.5 point favorite over Iowa. The total is set at over/under 38.5 total points scored by both teams combined.
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Updated on 10/12/26

Iowa vs. Michigan Prediction
In a pass-heavy college football world, these two teams prefer to hit the ground running. Literally. 56.9% of Michigan's offensive play calls have been runs, and 50.7% of Iowa's offensive play calls have been runs.
This should lead us to a low-scoring affair where the clock is always running and the total score is minuscule. These teams ranks 11th and 18th in overall defense, and both quarterbacks lack the ability to explode through the air. This will be a classic, low-scoring, Big Ten matchup.
Iowa vs. Michigan Prediction: Iowa vs. Michigan Under 38.5
(Pick from Dylan Wilkerson)
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