NFL Week 3 Odds: Lines, Spreads, Betting Trends for Every Game

NFL Week 3 Odds: Lines, Spreads, Betting Trends for Every Game

2026 NFL Week 3 Odds

Matchup Spread Total Moneyline
Packers vs
Falcons
-6 (-108)
+6 (-112)
o43.5 (-115)
u43.5 (-105)
-278
+225
Commanders vs
Seahawks
+7 (-112)
-7 (-108)
o40.5 (-102)
u40.5 (-118)
+245
-305
Steelers vs
Bengals
+3.5 (-105)
-3.5 (-115)
o42.5 (-110)
u42.5 (-110)
+160
-192
Lions vs
Jets
-6.5 (-110)
+6.5 (-110)
o47.5 (-115)
u47.5 (-105)
-305
+245
Giants vs
Titans
-2.5 (-120)
+2.5 (even)
o39.5 (-110)
u39.5 (-110)
-135
+114
Jaguars vs
Patriots
-3 (-105)
+3 (-115)
o45.5 (-110)
u45.5 (-110)
-162
+136
Dolphins vs
Chiefs
+11.5 (-112)
-11.5 (-108)
o46.5 (-105)
u46.5 (-115)
+575
-850
Colts vs
Texans
+2.5 (-105)
-2.5 (-115)
o43.5 (-110)
u43.5 (-110)
+120
-142
Browns vs
Panthers
+2.5 (even)
-2.5 (-120)
o42.5 (-108)
u42.5 (-112)
+124
-148
Bills vs
Chargers
-7 (-115)
+7 (-105)
o50.5 (-105)
u50.5 (-115)
-345
+275
Buccaneers vs
Vikings
+1.5 (-110)
-1.5 (-110)
o42.5 (-112)
u42.5 (-108)
even
-120
49ers vs
Cardinals
-8.5 (-105)
+8.5 (-115)
o47.5 (-115)
u47.5 (-105)
-485
+370
Saints vs
Raiders
-3 (-122)
+3 (+102)
o43.5 (-118)
u43.5 (-102)
-192
+160
Cowboys vs
Ravens
+3 (-105)
-3 (-115)
o52.5 (-112)
u52.5 (-108)
+140
-166
Broncos vs
Rams
+2.5 (-105)
-2.5 (-115)
o45.5 (-110)
u45.5 (-110)
+114
-135
Bears vs
Eagles
+4.5 (-110)
-4.5 (-110)
o41.5 (-115)
u41.5 (-105)
+185
-225

NFL Week 3 odds start a little slow, with Atlanta Falcons vs. Green Bay Packers. But the back end is pretty strong..

Among the notable matchups in Week 3 NFL odds: Los Angeles Chargers vs. Buffalo Bills, Baltimore Ravens vs. Dallas Cowboys, Los Angeles Rams vs. Denver Broncos and Philadelphia Eagles vs. Chicago Bears

Here’s everything you need to know about NFL odds Week 3: opening lines, spreads and betting trends for every game, as multiple oddsmakers provide insights on odds and action.

Prediction markets are in the mix, as well, so check out our Polymarket referral code and get in on the action today. Also, check back regularly for updates and use our bet365 bonus code to get the most out of your action.

Updated on 9/22/26

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2026 NFL Odds for Week 3

Atlanta Falcons vs. Green Bay Packers Odds

ATL @ GB Odds

  • Opening point spread: Packers -7
  • Opening moneyline: Packers -325/Falcons +270
  • Opening total: Over/Under 44.5 points scored
  • Time: 8:15 p.m. ET Thursday (Prime)

OPENING ODDS UPDATE: Green Bay (1-1 SU/0-2 ATS) hasn't been impressive thus far. In Week 2, the Packers were 3.5-point road favorites vs. the Jets and escaped with a 20-17 overtime victory.

But Atlanta (0-2 SU and ATS) showed far worse in Week 2. The Falcons were 2.5-point home underdogs vs. Carolina and got trucked 34-3.

Borgata Sports, a BetMGM shop in Atlantic City, opened the Packers -7 in NFL Week 1 odds. There was no Sunday night movement.

"Will we finally see a somewhat competent quarterback take a snap for Atlanta this season?" Borgata sportsook director Tom Gable said. "The Falcons are hoping Michael Penix is back on Thursday night, because things are quickly unraveling in the first two weeks of the season."

Indeed, third-string Cooper Rush started the first two games, as Penix recovers from a torn ACL suffered last season and Tua Tagovailoa dealing with an oblique injury.

"I’m not sure how much backing the public is going to give the Falcons here. Early money has been all on Green Bay," Gable said.

Los Angeles Chargers vs. Buffalo Bills Odds

LAC @ BUF Odds

  • Opening point spread: Bills -7
  • Opening moneyline: Bills -375/Chargers +290
  • Opening total: Over/Under 50 points scored
  • Time: 1 p.m. ET Sunday (FOX)

OPENING ODDS UPDATE: Buffalo (2-0 SU and ATS), which put up 77 points in the first two weeks, is coming off a mini-bye after a big Week 2 Thursday night win. The Bills topped Detroit 41-31 as 5.5-point home favorites.

Josh Allen accounted for five touchdowns, three passing and two rushing.

Los Angeles is already in an 0-2 SU and ATS hole, losing as a solid home favorite in both matchups while absolutely clobbering Circa Survivor contestants. In Week 2, laying 6.5 points vs. the Raiders, the Chargers tumbled 26-14.

In response, Borgata opened the Bills -7 at home in Week 3 NFL odds. The line was stable Sunday night.

"I don’t see any of the public wanting to play against Josh Allen at this point, after how he has looked in the first two weeks," Borgata sportsbook director Tom Gable said. "And the Chargers will come limping into this one. I could see this one getting above a touchdown."

Seattle Seahawks vs. Washington Commanders Odds

SEA @ WAS Odds

  • Opening point spread: Seahawks -6
  • Opening moneyline: Seahawks -250/Commanders +210
  • Opening total: Over/Under 41.5 points scored
  • Time: 1 p.m. ET Sunday (FOX)

OPENING ODDS UPDATE: Seattle (2-0 SU/1-1 ATS) looked much more like the defending Super Bowl champion in Week 2, even with Drew Lock still subbing for Sam Darnold. The Seahawks steamrolled Arizona 31-7 giving 4.5 points on the road.

Washington (0-2 SU/1-1 ATS) lost not only a game in Week 2, but QB Jayden Daniels to a dislocated left elbow. Daniels exited before halftime with the Commanders trailing Dallas 17-10, and Washington ultimately fell 37-20 catching 4.5 points on the road.

BetMGM opened Seattle -6 in NFL odds Week 3, with no movement Sunday night. But the total nudged from 41.5 to 41.

Cincinnati Bengals vs. Pittsburgh Steelers Odds

CIN @ PIT Odds

  • Opening point spread: Bengals -3.5
  • Opening moneyline: Bengals -175/Steelers +145
  • Opening total: Over/Under 43.5 points scored
  • Time: 1 p.m. ET Sunday (CBS)

OPENING ODDS UPDATE: Cincinnati is out of the gate at 2-0 SU and ATS, after an impressive Week 2 road win. The Bengals shut down Houston 20-6 as 2.5-point road underdogs.

Pittsburgh (1-1 SU and ATS) got almost no offense in a Week 2 setback. The Steelers got a field goal as time expired in the first half, and that was it in a 20-3 loss getting 4.5 points at New England.

Borgata Sports opened Bengals-Steelers at Cincy -3.5, with no Sunday night movement.

"There's some early Cincy money here, but nothing major," Borgata sportsbook director Tom Gable said.

New England Patriots vs. Jacksonville Jaguars Odds

NE @ JAC Odds

  • Opening point spread: Jaguars -2.5
  • Opening moneyline: Jaguars -145/Patriots +12
  • Opening total: Over/Under 44.5 points scored
  • Time: 1 p.m. ET Sunday (CBS)

OPENING ODDS UPDATE: Jacksonville (1-1 SU and ATS) held a 13-3 lead at Denver midway through the third quarter. But the Jags couldn't make it hold up, giving up the final 17 points in a 20-13 loss as 2.5-point pups.

New England (1-1 SU/2-0 ATS) put the clamps on Pittsburgh in Week 2. The Pats allowed only a field goal as the first half ended, coasting to a 20-3 victory as 4.5-point home favorites.

Patriots-Jags opened at Jacksonville -2.5 in Borgata Sports' NFL Week 3 odds.

"Early Jags money is laying less than the key number of 3. And the total has already ticked up a half-point," Borgata sportsbook director Tom Gable said of a Sunday night move from 44.5 to 45.

Kansas City Chiefs vs. Miami Dolphins Odds

KC @ MIA Odds

  • Opening point spread: Chiefs -10.5
  • Opening moneyline: Chiefs -600/Dolphins +450
  • Opening total: Over/Under 45 points scored
  • Time: 1 p.m. ET Sunday (CBS)

OPENING ODDS UPDATE: Kansas City (1-0 SU and ATS) is in the midst of its Week 2 assignment, hosting Indianapolis.

Miami (0-2 SU and ATS) looks every bit the team with a win total of 3.5, scoring just 26 points through two games. In Week 2, the Dolphins got rolled 35-13 catching 12.5 points at San Francisco.

BetMGM pegged K.C. a 10.5-point road favorite vs. Miami, with no movement Sunday night.

New York Jets vs. Detroit Lions Odds

NYJ @ DET Odds

  • Opening point spread: Lions -7
  • Opening moneyline: Lions -325/Jets +270
  • Opening total: Over/Under 48 points scored
  • Time: 1 p.m. ET Sunday (FOX)

OPENING ODDS UPDATE: Detroit (1-1 SU/0-2 ATS) dug itself into a 21-0 first-half hole and couldn't climb out at Buffalo. The Lions never got closer than 10 in the Week 2 Thurday nighter, losing 41-31 as 5.5-point underdogs.

New York (1-1 SU/2-0 ATS) led Green Bay 17-7 entering the fourth quarter. But the Jets couldn't make that lead hold up, losing 20-17 in overtime while covering as 3.5-point underdogs.

BetMGM opened the Lions -7 (-105) Sunday night, and the first move was toward the Jets, with Detroit dipping to -6.5 at various juice for a couple of hours. But late Sunday, the number returned to Lions -7 (-105).

The total also saw a little early back-and-forth, going from 48 to 47.5 briefly, then back to 48.

Houston Texans vs. Indianapolis Colts Odds

HOU @ IND Odds

  • Opening point spread: Texans -1.5
  • Opening moneyline: Texans -125/Colts +105
  • Opening total: Over/Under 43.5 points scored
  • Time: 1 p.m. ET Sunday (CBS)

OPENING ODDS UPDATE: Houston (0-2 SU and ATS) is off to a rough start for a playoff team considered to have one of the NFL's best defenses. In Week 2, the Texans closed as 2.5-point favorites and lost to Cincinnati 20-6.

Indianapolis (0-1 SU and ATS) is on the field right now, visiting Kansas City in the Week 2 Sunday night game.

The Texans opened -1.5 vs. the Colts in BetMGM's NFL odds Week 3 market, with no movement Sunday night.

Tennessee Titans vs. New York Giants Odds

TEN @ NYG Odds

  • Opening point spread: Giants -6
  • Opening moneyline: Giants -275/Titans +220
  • Opening total: Over/Under 43 points scored
  • Time: 1 p.m. ET Sunday (CBS)

LATEST UPDATE: New York (1-1 SU/1-1 ATS) saw a Week 2 that was very much opposite Week 1. On the Giants' first drive, Jaxson Dart suffered a knee injury that ended his night.

The G-Men then struggled behind Jameis Winston, losing to the Rams 28-6 as 6.5-point road underdogs. And Dart's status isn't yet known for Week 3.

Because of that, Titans-Giants is off the board late Tuesday night. On Sunday evening, DraftKings Sports opened Big Blue as a 5.5-point home favorite and moved to -6 in relatively short order.

However, if Dart is out, that number is sure to dip when this game re-emerges in NFL Week 3 odds. New York was taking 69% of early spread bets and practically all the early spread money before MNF and the Dart injury.

DK's total opened at 43.5 and toggled a couple times to 42.5 (Over -120), where it stood before Titans-Giants was taken down. The Over was drawing 58% of early bets/78% of early dollars.

OPENING ODDS UPDATE: New York still has Week 2 work to do. The Giants visit the Rams in the Monday night game.

Tennessee (0-2 SU/1-1 ATS) gave Philadelphia all it could handle, but it wasn't quite enough. The Titans took a 20-17 lead on a field goal with 1:56 remaining, but gave up a touchdown in the waning seconds to lose 24-20. Still, Tennessee covered as a 7-point home 'dog.

Titans-Giants opened at New York -6 in BetMGM's NFL Week 3 odds, with no Sunday night moves.

Carolina Panthers vs. Cleveland Browns Odds

CAR @ CLE Odds

  • Opening point spread: Panthers -3
  • Opening moneyline: Panthers -150/Browns +125
  • Opening total: Over/Under 40.5 points scored
  • Time: 1 p.m. ET Sunday (FOX)

OPENING ODDS UPDATE: Carolina (1-1 SU and ATS) ended a nearly five-year drought of not winning as a favorite. The Panthers pounded Atlanta 34-3 laying 2.5 points on the road, their first win as a favorite since Sept. 23, 2021.

But Cleveland (1-1 SU and ATS) pulled the far bigger surprise of Week 2. The Browns were 8.5-point road underdogs and stunned Tampa Bay 24-19, in a game that saw the last two minutes delayed for two hours by lightning.

Cleveland forced the Bucs to turn it over on downs in the waning seconds, with Tampa in the red zone.

BetMGM opened the Panthers -3 (-112) and adjusted to -3 (-118) on Sunday night. The total ticked up a half-point from 40.5 to 41.

Arizona Cardinals vs. San Francisco 49ers Odds

ARI @ SF Odds

  • Opening point spread: 49ers -8.5
  • Opening moneyline: 49ers -475/Cardinals +360
  • Opening total: Over/Under 47.5 points scored
  • Time: 4:05 p.m. ET Sunday (FOX)

OPENING ODDS UPDATE: San Francisco (2-0 SU and ATS) is hot out of the gate, outscoring the Rams and Cardinals by a combined 62-20. In Week 2 , the Niners rolled to a 35-13 victory giving 12.5 points to visiting Miami.

Arizona (1-1 SU and ATS) had a quick comedown from its Week 1 road upset of the Chargers. The Cardinals had no answer for defending Super Bowl champion Seattle, tumbling 31-7 as 4.5-point home underdogs.

BetMGM opened and remains 49ers -8.5 late Sunday night. But the total did get a nudge, from 47.5 to 48.

Minnesota Vikings vs. Tampa Bay Buccaneers Odds

MIN @ TB Odds

  • Opening point spread: Vikings -2.5
  • Opening moneyline: Vikings -135/Buccaneers +110
  • Opening total: Over/Under 44.5 points scored
  • Time: 4:05 p.m. ET Sunday (FOX)

OPENING ODDS UPDATE: Tampa Bay (0-2 SU and ATS) was dealt one of the bigger upsets of this young season so far. The Bucs were 8.5-point home faves vs. Cleveland and got upended 24-19, in a game that had a two-hour lightning delay before the final two minutes were played.

The Bucs had the ball most of those two minutes and drove to the Browns 20 before ultimately turning it over on downs.

Minnesota (2-0 SU and ATS) notched a Week 2 upset, as well, though in a rock fight of a game. The Vikings went to Chicago as 4.5-point 'dogs and exited with a 9-3 victory in a field-goal fest. The Vikes were aided by Bears QB Caleb Williams (hamstring) exiting with 8:30 remaining.

BetMGM actually opened the Vikes as 2.5-point road favorites vs. the Bucs in Week 3 NFL odds. There was no movement Sunday night.

Baltimore Ravens vs. Dallas Cowboys Odds

BAL @ DAL Odds

  • Opening point spread: Ravens -3
  • Opening moneyline: Ravens -160/Cowboys +130
  • Opening total: Over/Under 52 points scored
  • Time: 4:25 p.m. ET Sunday (CBS)

OPENING ODDS UPDATE: Baltimore (1-1 SU and ATS) was another big upset victim on NFL Week 2 Sunday. The Ravens were 8.5-point home favorites vs. New Orleans and surprisingly lost outright 24-17.

Baltimore entered the fourth quarter with a 17-9 lead, but scored no more and gave up two touchdowns, the second with just 1:28 left.

Dallas (1-1 SU and ATS) took advantage of Washington QB Jayden Daniels (elbow) exiting before halftime. The Cowboys went on to a 37-20 victory as 4.5-point home favorites.

Borgata Sports opened the Ravens -3 vs. the Cowboys in NFL Week 1 odds. There was no movement Sunday night for this neutral-site affair in Rio de Janeiro.

"The Ravens losing to the Saints was one of the bigger upsets of the weekend," Borgata sportsbook director Tom Gable said. "Now they’ll head to Brazil to face a Dallas team that bounced back nicely after a Week 1 loss.

"This has the potential to be a shootout. But with the travel to South America and field conditions, anything is possible."

Las Vegas Raiders vs. New Orleans Saints Odds

LV @ NO Odds

  • Opening point spread: Saints -3
  • Opening moneyline: Saints -175/Raiders +135
  • Opening total: Over/Under 44 points scored
  • Time: 4:25 p.m. ET Sunday (CBS)

OPENING ODDS UPDATE: Las Vegas is a surprising 2-0 SU and ATS. In Week 2, the Raiders were 6.5-point road 'dogs vs. the Chargers and scored the final 14 points plus a safety in a 26-14 victory.

New Orleans (1-1 SU/2-0 ATS) would be 2-0 if not for a failed 2-point conversion in overtime at Detroit in Week 1. The Saints rebounded with a big Week 2 upset, knocking off Baltimore 24-17 as 8.5-point road pups.

New Orleans put up two fourth-quarter TDs, turning a 17-9 deficit into the winning margin.

BetMGM opened the Saints -3 (-118) Sunday night and adjusted to -3 (-115).

Los Angeles Rams vs. Denver Broncos Odds

LA @ DEN Odds

  • Opening point spread: Rams -2.5
  • Opening moneyline: Rams -145/Broncos +120
  • Opening total: Over/Under 45.5 points scored
  • Time: 8:20 p.m. ET Sunday (NBC)

LATEST UPDATE: The Rams (1-1 SU and ATS) rebounded just fine from a blowout Week 1 loss to San Francisco. Los Angeles rolled over the New York Giants 28-6 in Monday night football and now preps for its third straight prime-time game.

DraftKings Sports opened Rams-Broncos at L.A. -2.5 (-115) Sunday evening and adjusted to -2.5 flat in short order. On Monday evening, the Rams briefly dipped to -1.5 (-115) before returning to -2.5.

Early spread play is actually leaning into the home 'dog Broncos, at 72% of tickets/67% of money.

DK's total is steady at 45.5, with 60% of early bets on the Over, but practically all the early money — which is certainly very light — on the Under.

OPENING ODDS UPDATE: Los Angeles (0-1 SU and ATS) isn't yet out of Week 2, while trying to rebound from a blowout Week 1 loss to San Francisco. The Rams host the Giants on Monday night.

Denver (1-1 SU and ATS) rebounded from a Week 1 blowout loss to Kansas City, but needed a rally to do so. The Broncos trailed Jacksonville 13-3 midway through the third quarter, but did the rest of the scoring in a 20-13 victory giving 2.5 points at home.

That didn't impress oddsmakers. Borgata Sports opened L.A. -2.5 in the Sunday night game on the Week 3 NFL odds board.

"The Broncos had a nice come-from-behind win against the Jags to cover the number," Borgata sportsbook director Tom Gable said. "We still are unsure of Puka Nacua’s status for Monday night against the Giants. So I certainly don’t want to speculate on this game, this far in advance."

Philadelphia Eagles vs. Chicago Bears Odds

PHI @ CHI Odds

  • Opening point spread: Eagles -4
  • Opening moneyline: Eagles -200/Bears +170
  • Opening total: Over/Under 43.5 points scored
  • Time: 8:15 p.m. ET Monday (ESPN/ABC)

OPENING ODDS UPDATE: Chicago (1-1 SU and ATS) put up 59 points in Week 1, then lost Caleb Williams in the fourth quarter of Week 2 while scoring merely a field goal. From penthouse to outhouse.

The Bears netted only a first-quarter field goal in a 9-3 snoozer of a loss as 4.5-point home favorites vs. Minnesota.

Meanwhile, Philadelphia (2-0 SU/0-2 ATS) barely escaped Tennessee unscathed. The Eagles gave up a touchdown with 1:56 left to fall behind 20-17, but a Darius Cooper 3-yard TD catch in the waning seconds sealed a 24-20 victory.

The Eagles opened as 4-point road favorites vs. the Bears in Borgata Sports' NFL odds Week 3.

"With Caleb Williams suffering the hamstring injury, the Eagles may catch a break," Borgata sportsbook director Tom Gable said. "But Saquon Barkley’s availability may be in doubt, after suffering a stinger in the Eagles-Titans game.

"Early money has come in on Philly here."