2026 College Football Odds Week 4: Lines, Spreads, Betting Trends on Biggest Games

2026 College Football Odds Week 4: Lines, Spreads, Betting Trends on Biggest Games

The College Football Odds Week 4 market is littered with big SEC showdowns.

Texas vs. Tennessee, Texas A&M vs. LSU, Ole Miss vs. Florida and Oklahoma vs. Georgia lead the way in College Football Week 4 odds. And in the Big Ten, Oregon vs. USC is a key contest.

Here’s everything you need to know about 2026 college football odds Week 4: opening lines, spreads and betting trends for the biggest games, as multiple oddsmakers provide insights on Week 4 college football odds and action.

Prediction markets are in the mix, as well, so check out our Kalshi referral code and get in on the action today. Also, check back regularly for updates and use our bet365 bonus code to get the most out of your action.

Updated on 10/12/26

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2026 College Football Odds for Week 4

Texas A&M vs. LSU Odds

TA&M @ LSU Odds

  • Opening point spread: LSU -9
  • Opening moneyline: LSU -350/Texas A&M +290
  • Opening total: Over/Under 53.5 points scored
  • Time: 7:30 p.m. ET Saturday (ABC)

LATEST UPDATE: LSU is 9-point chalk in BetMGM's college football Week 4 odds, as of 6:30 p.m. ET Saturday, an hour before kickoff. The Tigers just moved off -8.5, and actually got to -9.5 briefly on Friday morning, before falling back to -9/8.5.

The road favorite is plenty popular tonight.

"We're seeing plenty of support for LSU, spread and moneyline. There's two times the bets and three times the money compared to Texas, spread and moneyline," BetMGM trading manager Adair Horne said, noting that action includes all bets (straight/parlays etc.)

"The best result for us would be a Texas A&M upset, and bettors would get all the money with an LSU cover."

BetMGM's total is 52.5, down from a 53.5 opener but up from 51.5 this morning. Horne said betting is "very even."

THIRD UPDATE: Anyone who jumped on LSU over the summer, at -3.5, is feeling pretty good. Hard Rock Bet reopened this matchup Sunday at LSU -8.5, and the Tigers advanced to -10.5 by Sunday night.

Most of the week, the number has been at some iteration of LSU -9.5. As of 4:30 p.m. ET Thursday, it's Tigers -9.5 (-115). LSU is netting 54% of early spread bets, while early spread money is nearly even. Road underdog A&M is getting 61% of moneyline bets/62% of moneyline cash.

Hard Rock's total is at 51.5 (Over -115), after opening at 53.5 and making a stop at 52.5 early in the week. The Over is getting about 66% of tickets, on light action so far.

SECOND UPDATE: As of 3:30 p.m. ET Thursday, LSU is -9 in Borgata Sports' college football Week 4 odds. That's up a tick from the opener of Tigers -8.5.

"The chances for a playoff appearance for Texas A&M could very much be in jeopardy here," Borgata sportsbook director Tom Gable said. "LSU, coming off a loss in a very tough environment at Ole Miss, will be looking to bounce back. It’s been mostly LSU money early here."

Borgata's total is at 52.5 from a 53.5 opener.

OPENING ODDS UPDATE: No. 10 LSU (2-1 SU/1-2 ATS) couldn't quite complete a big rally as a short road favorite vs. Ole Miss. The Tigers were in a 24-7 hole halftime hole and came back to tie it at 24 in the fourth quarter, but ultimately lost 32-24 laying 3 points.

No. 23 Texas A&M (2-1 SU and ATS) already borrowed some big trouble early in the season. The Aggies were 16.5-point home favorites vs. Kentucky and were dealt a 31-21 upset loss in Week 3.

That prompted Circa to open LSU as a 9-point home favorite vs. A&M. In less than two hours Sunday, the Tigers advanced to -10. The total was also on the move, dropping from 53.5 to 52.

Oregon vs. USC Odds

  • Opening point spread: Oregon -2.5
  • Opening moneyline: Oregon -160/USC +140
  • Opening total: Over/Under 62.5 points scored
  • Time: 7:30 p.m. ET Saturday (NBC)

LATEST UPDATE: BetMGM has Oregon -3.5 in Week 4 college football odds, as of 6:30 p.m. ET Saturday, an hour before kickoff. The Ducks opened -1, then climbed the ladder Sunday to -1.5/-2/-2.5/-3.

Oregon first got to -3.5 Friday night and has spent most of Saturday at various iterations of -3.5.

"Strongle handle here than on Texas A&M-LSU, with the game being more competitive," BetMGM trading manager Adair Horne said. "Bettors aren't able to decide a side on this one, with almost an exact split of bets across both options (spread/moneyline)."

Spread cash is leaning more toward Oregon, though, at 60%.

The total is at 60.5, down from a 62.5 opener and 61.5 this morning.

"We're seeing 80% of the handle on the Over. So bettors are expecting a shootout," Horne said.

THIRD UPDATE: Oregon is -2.5 (-120) in Hard Rock Bet's college football odds Week 4, as of 5 p.m. ET Thursday. The Ducks opened -1.5 and quickly went to -2.5 Sunday, then spent the first half of the week at various iterations of -3.5.

Early Thursday afternoon, Oregon dipped from -3.5 (even) to -2.5 (-120). Home 'dog USC is actually landing 56% of spread bets/54% of spread oney. On the moneyline, tickets are close, at 54% on Oregon, but 90% of cash is on the Ducks.

Hard Rock's total is at 62.5 (Under -115), and in fact, it's been at some iteration of 62.5 all week. The Over is getting 88% of tickets/86% of money.

SECOND UPDATE: At 3:30 p.m. ET Tuesday, Oregon is 3-point road chalk in Borgata Sports' Week 4 college football odds. On Sunday, the Ducks opened -1.5.

"It took Portland State to finally make Oregon look OK for a game.  But now it’s back to real competition against USC," Borgata sportsbook director Tom Gable said. "The Trojans return to the Coliseum after their road trip to Rutgers.

"We know these California Big Ten teams don’t travel to the East Coast well, and the Trojans had a tough time in the Garden State, but managed to get the job done. This could be a telling game for both teams, with plenty of points scored."

Indeed, the total is at 62.5.

OPENING ODDS UPDATE: No. 12 USC (4-0 SU/1-3 ATS) has done what's necessary to win, but hasn't been effective at covering. In Week 3, the Trojans were hefty 21.5-point favorites at Rutgers and held on for a 42-35 victory.

No. 20 Oregon (2-1 SU/1-2 ATS) struggled in its first two games, including a huge Week 2 upset loss at Oklahoma State. The Ducks found the cure in the form of an FCS opponent.

Oregon pummeled Portland State 84-0, easily covering as a massive 59.5-point home favorite.

The Ducks opened as 2.5-point road faves at Circa Sports, and that number was rock-solid Sunday, with no movement. Monday morning, though, Oregon advanced to -3.

Check out our full Oregon vs. USC prediction.

Ole Miss vs. Florida Odds

  • Opening point spread: Florida -3
  • Opening moneyline: Florida -170/Ole Miss +150
  • Opening total: Over/Under 59.5 points scored
  • Time: 3:30 p.m. ET Saturday (ABC)

Before you wager, check out Action Network's Ole Miss vs. Florida Best Bets!

LATEST UPDATE: Florida is up to a 4-point favorite at BetMGM, as of 2 p.m. ET, 90 minutes pre-kickoff. In fact, that move just occurred, from Gators -3.5 to -4, followed by a juice adjustment to -4 (-102). And it's reduced juice, so Ole Miss is +4 (-108).

But the need belies the odds movement.

"Florida is gonna be our biggest need of the slate. Ole Miss moneyline and +3/+3.5 are the most popular plays of the weekend. However, sharps are riding with the Gators," BetMGM trading manager Seamus Magee said.

The total is at 58.5, which matches the opener, but is well off the 61.5 high point early in the week. Still, Magee said Under is the preference.

FOURTH UPDATE: This is the most intriguing game on the menu. Friday night, Ole Miss running back Kewan Lacy (shoulder) was downgraded to doubtful. But BetMGM and others didn't move at all off that, keeping Florida at -3.5, where it remains at 9:30 a.m. ET Saturday.

BetMGM was among the early openers on this game, at Gators -1 last Saturday. Florida was out to -2.5 by Sunday morning, -3 Sunday afternoon and -3.5 Sunday night. The line toggled between Florida -3/-3.5 during the week and has been steady at -3.5, at various juice, since Friday morning.

Six hours pre-kickoff, Ole Miss is getting 64% of spread tickets/56% of spread money. But in terms of actual ticket count, the Rebels are taking the second-most spread bets of any Top 25 team today and are No. 3 in money count.

Further, on BetMGM's moneyline, 85% of tickets/70% of dollars are on Ole Miss, and by tickets, the Rebels are the most-bet underdog to win.

THIRD UPDATE: The Gators are -3.5 (-105) in Hard Rock Bet's Week 4 college football odds, as of 4:30 p.m. ET Thursday. Florida opened -1.5 and by Sunday night went to -3.5, with only juice adjustments since then.

So far, it's all Ole Miss on the spread and moneyline. The Rebels are landing 85% of spread bets/91% of spread money, and 89% of moneyline bets/87% of moneyline dollars.

Hard Rock's total is at 58.5 (Over -115), after opening 58.5 (Under -115), peaking at 60.5 (Over -115) Sunday and sitting at 59.5 early in the week. It's all Over action, at 94% of bets/98% of cash.

SECOND UPDATE: Florida is up to 3.5-point home chalk in Borgata Sports' college football Week 4 odds, as of 3 p.m. ET Tuesday. The Gators opened -2.5 on Sunday.

"Respected early money on Florida, which is coming off a win and cover on the road against Auburn," Borgata sportsbook director Tom Gable said. "Ole Miss will be coming down from an emotional win on Saturday night against Lane Kiffin and LSU.

"Florida has shown itself to be an early contender in the SEC."

The total is on the move at Borgata, as well, climbing from 58.5 to 61.5 by Monday afternoon, then backing up to 58.5 Tuesday.

OPENING ODDS UPDATE: No. 4 Ole Miss (3-0 SU/2-1 ATS) got an early-season signature win in Week 3. The Rebels closed as 3-point home underdogs to LSU and notched a 32-24 victory, fending off the Tigers after blowing a 24-7 halftime lead.

Florida (3-0 SU/2-1 ATS) entered the rankings at No. 21 this week. That was largely due to the Gators' 44-39 Week 3 victory at Auburn as 2.5-point favorites.

And Circa Sports then made Florida a 3-point home favorite vs. Ole Miss. Interestingly, late Sunday night, the Gators advanced to -3.5. The total was on the move much sooner, jumping from 59.5 to 61 within two hours.

Check out our full Ole Miss vs. Florida prediction.

Iowa vs. Michigan Odds

  • Opening point spread: Michigan -4
  • Opening moneyline: Michigan -225/Iowa +195
  • Opening total: Over/Under 38 points scored
  • Time: 3:30 p.m. ET Saturday (CBS)

Don't wager without first checking in on Action Network's Iowa vs. Michigan Predictions!

LATEST UPDATE: BetMGM has the Wolverines -5 as of 2:30 p.m. ET Saturday, an hour before kickoff. That matches the opening number, but the line spent time at -4.5 early in the week and touched -5.5 several times, most recently early this afternoon.

"Iowa +5.5 is getting some decent action. We'd like to see Michigan cover and possibly see this one go Over. Lots of action on the Under here today," BetMGM trading manager Seamus Magee said.

The total is at 40.5 (Under -115), actually well up from a 37.5 opener. It's up 2 points today alone.

THIRD UPDATE: Michigan is 5.5-point home chalk in Hard Rock Bet's college football odds Week 4 market, as of 4:30 p.m. ET Thursday. The number toggled between the -4.5 opener/-5.5 a couple times this week, most recently Thursday morning.

Road underdog Iowa is netting 68% of spread tickets, but money is close to even. The Hawkeyes are quite popular on the moneyline, at 85% of tickets/88% of money.

Hard Rock's total is at 38.5 (Under -115), up from a 37.5 opener. The Under is getting 62% of tickets/54% of money.

SECOND UPDATE: Borgata Sports opened Michigan -5.5, with no movement so far, as of 3 p.m. ET Tuesday.

"Not much has come in early on this game," Borgata sportsbook director Tom Gable said. "Turnovers will be key in how this game plays out.  If Michigan can take care of the ball, it should be able to cover this number.  But easier said than done with Bryce Underwood.

Borgata's total hasn't moved off 38.5.

OPENING ODDS UPDATE: In Week 3, Michigan (3-0 SU/2-1 ATS) looked as if it might replicate its poor Week 1 showing vs. Western Michigan. The Wolverines closed as 34.5-point home favorites vs. UTEP, yet led just 17-14 at halftime.

But it was all Big Blue from there, as No. 18 Michigan scored the 35 of the final 38 points in a 52-17 win and cover.

No. 17 Iowa (3-0 SU/2-1 ATS) put up its second offensive explosion in three games. The Hawkeyes plastered FCS outfit Northern Iowa 55-0 laying 37.5 points at home.

Michigan opened -4 in Circa's college football odds Week 4. In short order, the Wolverines jumped to -5, then returned to -4 within 30 minutes. But by Sunday evening Michigan was stable at -5, and on Monday morning, the number went to -6.

The total quickly jumped from 38 to 39.5, but that didn't last long before returning to 38 Sunday afternoon.

Check out our complete Iowa vs. Michigan prediction.

Oklahoma vs. Georgia Odds

  • Opening point spread: Georgia -14.5
  • Opening moneyline: Georgia -550/Oklahoma +425
  • Opening total: Over/Under 43.5 points scored
  • Time: 3:30 p.m. ET Saturday (TV TBA)

LATEST UPDATE: As of 2:30 p.m. ET Saturday, an hour before kickoff, the Bulldogs are down to -12 in BetMGM's college football Week 4 odds. Georgia opened -14 and briefly touched -14.5 early in the week, and the line spent much of the past couple days at various iterations of -13.5.

But it dipped to Bulldogs -13 this morning, then in the past hour to -12.5/-12. That said:

"It's one-way traffic on Georgia. We'll be hoping that the Sooners can keep this one within the number," BetMGM trading manager Seamus Magee said.

The total is at 43.5 (Over -125), down from a 46.5 opener. But Magee said there's not much of a decision there.

THIRD UPDATE: Georgia is -13.5 (-115) in Hard Rock Bet's college football Week 4 odds, as of 4:30 p.m. ET Thursday. That's where the Bulldogs opened, and they spent time at -14.5 early in the week.

Georgia is plenty popular early on the spread, nabbing 91% of tickets/96% of money.

Hard Rock's total is at 44.5, sitting there since Monday after opening at 45.5 and dropping to 43.5. Ticket count is dead even, and 55% of cash is on the Under.

SECOND UPDATE: Georgia is laying 13.5 points at home in Borgata Sports' college football odds Week 4, as of 3:30 p.m. ET Tuesday. The Bulldogs opened -14 on Sunday.

"Georgia has had a relatively easy schedule to start the season," Borgata sportsbook director Tom Gable said. "The line for this game in the summer was Georgia -10. But [QB] John Mateer has not looked good for the Sooners this season.

"Oklahoma will need a good effort out of him in order to keep this within two touchdowns."

The total is more on the move early at Borgata, dipping from 46.5 to 44.5.

OPENING ODDS UPDATE: No. 2 Georgia (3-0 SU and ATS) should finally get tested after three easy wins and covers. In Week 3, the Bulldogs rolled over Arkansas 45-17 laying 24.5 points on the road.

Oklahoma (2-1 SU/1-2 ATS) didn't exactly cover itself in glory against a perceived well-overmatched opponent in Week 3. The Sooners were 21.5-point home favorites vs. New Mexico and didn't even score 22, let alone cover in a 14-6 victory.

And that was after a 17-10 loss laying 5.5 points at Michigan.

With that in mind, Circa Sports opened Georgia -14.5. But the first move was toward the big road 'dog Sooners, with the Bulldogs nudging to -14 a few minutes after opening.

The total was more so on the move, going from 43.5 to 45 right out of the gate, then receding to 44 and 42.5. After 40 minutes, the number settled at 43.5 again.

Texas vs. Tennessee Odds

  • Opening point spread: Texas -5.5
  • Opening moneyline: Texas -210/Tennessee +180
  • Opening total: Over/Under 57 points scored
  • Time: Noon ET Saturday (ABC)

LATEST UPDATE: Arch Manning and the Longhorns are laying 5.5 points in BetMGM's college football odds Week 4 market. And it's reduced juice, with Texas -5.5 (-105)/Tennessee +5.5 (-108) as of 11 a.m. ET Saturday, an hour before kickoff.

"We have a public 'dog today. The book is gonna need Arch and Texas to cover -5," BetMGM trading manager Seamus Magee said. "We would like to see this stay under the total, as well."

That total is currently at 54.5 (Over -115), down from a 56.5 opener and sitting at various iterations of 54.5 since Thursday night.

THIRD UPDATE: As of 4 p.m. ET Thursday, this line continues to move toward Tennessee. Hard Rock Bet dipped from Texas -4.5 (-105) to -3.5 (-115) earlier this afternoon in college football Week 4 odds.

The Longhorns opened -5.5 and dialed down to -3.5 (-115) by Sunday night. Then the number rebouned to Texas -4.5/-5.5 Monday, and returned to -4.5 Wednesday before again getting to -3.5 Thursday.

Spread tickets are close, with 53% on Tennessee, but 61% of spread money is on Texas. Vols moneyline is getting some attention, at 70% of tickets/59% of money.

Hard Rock's total as at 55.5 (Under -115), after opening at 57.5 (Under -115) and having a couple early stints at 56.5. The Under is seeing 64% of tickets/69% of money.

SECOND UPDATE: Texas is 5.5-point road chalk in Borgata Sports' Week 4 college football oddsm, as of 3 p.m. ET Tuesday. That's up a tick from Borgata's Longhorns -5 opener, after which there was a notable early drop.

"Early money has come in on Texas, along with the Under," Borgata sportsbook director Tom Gable said. "If you were watching an odds screen on Sunday night, you saw this one drop to around 3.5, getting the game set up to come back on Texas, which is exactly what happened. Texas got steamed back up."

The total is at 55.5 from a 56.5 opener.

OPENING ODDS UPDATE: No. 1 Texas (3-0 SU/1-2 ATS) got a much lighter test in Week 3, after a stirring Week 2 comeback victory over Ohio State. The Longhorns had little trouble dispatching UTSA 30-6, but failed to cash as 30.5-point home favorites.

No. 14 Tennessee (3-0 SU/1-2 ATS) similarly had a lightweight Week 3 foe in Kennessaw State. The Vols rolled to a 42-9 win, but also couldn't cover as 35.5-point favorites.

Circa Sports, whose opening numbers are well-respected and often draw sharp play, opened Texas -5.5 on Sunday afternoon. Within a couple hours, that number dropped to Longhorns -4 in college football Week 4 odds.

But Monday morning, Texas returned to -5.5.

The total did a little back-and-forth dance, opening at 57, dropping to 55 within 40 minutes, then returning to 57 about an hour after that.

Check out our full Texas vs. Tennessee prediction.

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