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Featured Last Updated Sep 21 2026, 12:30 PM

2026 College Football Odds Week 4: Lines, Spreads, Betting Trends on Biggest Games

Patrick Everson
Patrick Everson Sports Betting Expert
12 minute read
2026 College Football Odds Week 4: Lines, Spreads, Betting Trends on Biggest Games

The College Football Odds Week 4 market is littered with big SEC showdowns.

Texas vs. Tennessee, Texas A&M vs. LSU, Ole Miss vs. Florida and Oklahoma vs. Georgia lead the way in College Football Week 4 odds. And in the Big Ten, Oregon vs. USC is a key contest.

Here’s everything you need to know about 2026 college football odds Week 4: opening lines, spreads and betting trends for the biggest games, as multiple oddsmakers provide insights on Week 4 college football odds and action.

Prediction markets are in the mix, as well, so check out our Kalshi referral code and get in on the action today. Also, check back regularly for updates and use our bet365 bonus code to get the most out of your action.

Updated on 9/21/26

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2026 College Football Odds for Week 4

Texas vs. Tennessee Odds

TEX @ TENN Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Texas Longhorns 327 Texas
-7 -110 N/A N/A -3.5 -102 + -3.5 -104 + N/A N/A N/A -4.5 -112  
Tennessee Volunteers 328 Tennessee
+7 -110 N/A N/A +3.5 -118 + +3.5 -118 + N/A N/A N/A +4.5 -108  
Texas Longhorns 327 Texas
o56.5 -112 N/A N/A o28.5 -105 + o28.5 -104 + N/A N/A N/A o56.5 -108  
Tennessee Volunteers 328 Tennessee
u56.5 -108 N/A N/A u28.5 -115 + u28.5 -118 + N/A N/A N/A u56.5 -112  
Texas Longhorns 327 Texas
-258 N/A N/A -180 + -174 + N/A N/A N/A -205  
Tennessee Volunteers 328 Tennessee
+210 N/A N/A +150 + +142 + N/A N/A N/A +170  
Texas Longhorns 327 Texas
-7 -110 N/A N/A -0.5 even + -1.5 +106 + N/A N/A N/A -4.5 -112  
Tennessee Volunteers 328 Tennessee
+7 -110 N/A N/A +0.5 -130 + +1.5 -128 + N/A N/A N/A +4.5 -108  
Texas Longhorns 327 Texas
o56.5 -112 N/A N/A o12.5 -120 + o13.5 -102 + N/A N/A N/A o56.5 -108  
Tennessee Volunteers 328 Tennessee
u56.5 -108 N/A N/A u12.5 -110 + u13.5 -120 + N/A N/A N/A u56.5 -112  
Texas Longhorns 327 Texas
-258 N/A N/A -160 + -152 + N/A N/A N/A -205  
Tennessee Volunteers 328 Tennessee
+210 N/A N/A +124 + +130 + N/A N/A N/A +170  
Texas Longhorns 327 Texas
-7 -110 N/A N/A N/A -1.5 -108 + N/A N/A N/A -4.5 -112  
Tennessee Volunteers 328 Tennessee
+7 -110 N/A N/A N/A +1.5 -114 + N/A N/A N/A +4.5 -108  
Texas Longhorns 327 Texas
o56.5 -112 N/A N/A N/A o16.5 -112 + N/A N/A N/A o56.5 -108  
Tennessee Volunteers 328 Tennessee
u56.5 -108 N/A N/A N/A u16.5 -108 + N/A N/A N/A u56.5 -112  
Texas Longhorns 327 Texas
-258 N/A N/A N/A -156 + N/A N/A N/A -205  
Tennessee Volunteers 328 Tennessee
+210 N/A N/A N/A +132 + N/A N/A N/A +170  
Texas Longhorns 327 Texas
-7 -110 N/A N/A N/A -1.5 +112 + N/A N/A N/A -4.5 -112  
Tennessee Volunteers 328 Tennessee
+7 -110 N/A N/A N/A +1.5 -136 + N/A N/A N/A +4.5 -108  
Texas Longhorns 327 Texas
o56.5 -112 N/A N/A N/A o12.5 -122 + N/A N/A N/A o56.5 -108  
Tennessee Volunteers 328 Tennessee
u56.5 -108 N/A N/A N/A u12.5 -100 + N/A N/A N/A u56.5 -112  
Texas Longhorns 327 Texas
-258 N/A N/A N/A -154 + N/A N/A N/A -205  
Tennessee Volunteers 328 Tennessee
+210 N/A N/A N/A +120 + N/A N/A N/A +170  
Texas Longhorns 327 Texas
-7 -110 N/A N/A N/A -1.5 +112 + N/A N/A N/A -4.5 -112  
Tennessee Volunteers 328 Tennessee
+7 -110 N/A N/A N/A +1.5 -136 + N/A N/A N/A +4.5 -108  
Texas Longhorns 327 Texas
o56.5 -112 N/A N/A N/A o14.5 +110 + N/A N/A N/A o56.5 -108  
Tennessee Volunteers 328 Tennessee
u56.5 -108 N/A N/A N/A u14.5 -134 + N/A N/A N/A u56.5 -112  
Texas Longhorns 327 Texas
-258 N/A N/A N/A -138 + N/A N/A N/A -205  
Tennessee Volunteers 328 Tennessee
+210 N/A N/A N/A +118 + N/A N/A N/A +170  
  • Opening point spread: Texas -5.5
  • Opening moneyline: Texas TBA/Tennessee TBA
  • Opening total: Over/Under 57 points scored
  • Time: Noon ET Saturday (ABC)

OPENING ODDS UPDATE: No. 1 Texas (3-0 SU/1-2 ATS) got a much lighter test in Week 3, after a stirring Week 2 comeback victory over Ohio State. The Longhorns had little trouble dispatching UTSA 30-6, but failed to cash as 30.5-point home favorites.

No. 14 Tennessee (3-0 SU/1-2 ATS) similarly had a lightweight Week 3 foe in Kennessaw State. The Vols rolled to a 42-9 win, but also couldn't cover as 35.5-point favorites.

Circa Sports, whose opening numbers are well-respected and often draw sharp play, opened Texas -5.5 on Sunday afternoon. Within a couple hours, that number dropped to Longhorns -4 in college football Week 1 odds.

But Monday morning, Texas returned to -5.5.

The total did a little back-and-forth dance, opening at 57, dropping to 55 within 40 minutes, then returning to 57 about an hour after that.

Iowa vs. Michigan Odds

  • Opening point spread: Michigan -4
  • Opening moneyline: TBA/TBA
  • Opening total: Over/Under 38 points scored
  • Time: 3:30 p.m. ET Saturday (CBS)

OPENING ODDS UPDATE: In Week 3, Michigan (3-0 SU/2-1 ATS) looked as if it might replicate its poor Week 1 showing vs. Western Michigan. The Wolverines closed as 34.5-point home favorites vs. UTEP, yet led just 17-14 at halftime.

But it was all Big Blue from there, as No. 18 Michigan scored the 35 of the final 38 points in a 52-17 win and cover.

No. 17 Iowa (3-0 SU/2-1 ATS) put up its second offensive explosion in three games. The Hawkeyes plastered FCS outfit Northern Iowa 55-0 laying 37.5 points at home.

Michigan opened -4 in Circa's college football odds Week 4. In short order, the Wolverines jumped to -5, then returned to -4 within 30 minutes. But by Sunday evening Michigan was stable at -5.

The total quickly jumped from 38 to 39.5, but that didn't last long before returning to 38 Sunday afternoon.

Ole Miss vs. Florida Odds

  • Opening point spread: Florida -3
  • Opening moneyline: TBA/TBA
  • Opening total: Over/Under 59.5 points scored
  • Time: 3:30 p.m. ET Saturday (ABC)

OPENING ODDS UPDATE: No. 4 Ole Miss (3-0 SU/2-1 ATS) got an early-season signature win in Week 3. The Rebels closed as 3-point home underdogs to LSU and notched a 32-24 victory, fending off the Tigers after blowing a 24-7 halftime lead.

Florida (3-0 SU/2-1 ATS) entered the rankings at No. 21 this week. That was largely due to the Gators' 44-39 Week 3 victory at Auburn as 2.5-point favorites.

And Circa Sports then made Florida a 3-point home favorite vs. Ole Miss. Interestingly, late Sunday night, the Gators advanced to -3.5. The total was on the move much sooner, jumping from 59.5 to 61 within two hours.

Oklahoma vs. Georgia Odds

  • Opening point spread: Georgia -14.5
  • Opening moneyline: Georgia TBA/Oklahoma TBA
  • Opening total: Over/Under 43.5 points scored
  • Time: 3:30 p.m. ET Saturday (TV TBA)

OPENING ODDS UPDATE: No. 2 Georgia (3-0 SU and ATS) should finally get tested after three easy wins and covers. In Week 3, the Bulldogs rolled over Arkansas 45-17 laying 24.5 points on the road.

Oklahoma (2-1 SU/1-2 ATS) didn't exactly cover itself in glory against a perceived well-overmatched opponent in Week 3. The Sooners were 21.5-point home favorites vs. New Mexico and didn't even score 22, let alone cover in a 14-6 victory.

And that was after a 17-10 loss laying 5.5 points at Michigan.

With that in mind, Circa Sports opened Georgia -14.5. But the first move was toward the big road 'dog Sooners, with the Bulldogs nudging to -14 a few minutes after opening.

The total was more so on the move, going from 43.5 to 45 right out of the gate, then receding to 44 and 42.5. After 40 minutes, the number settled at 43.5 again.

Texas A&M vs. LSU Odds

  • Opening point spread: LSU -9
  • Opening moneyline: LSU TBA/Texas A&M TBA
  • Opening total: Over/Under 53.5 points scored
  • Time: 7:30 p.m. ET Saturday (ABC)

OPENING ODDS UPDATE: No. 10 LSU (2-1 SU/1-2 ATS) couldn't quite complete a big rally as a short road favorite vs. Ole Miss. The Tigers were in a 24-7 hole halftime hole and came back to tie it at 24 in the fourth quarter, but ultimately lost 32-24 laying 3 points.

No. 23 Texas A&M (2-1 SU and ATS) already borrowed some big trouble early in the season. The Aggies went to Kentucky as 16.5-point favorites and left with a 31-21 upset loss in Week 3.

That prompted Circa to open LSU as a 9-point home favorite vs. A&M. In less than two hours Sunday, the Tigers advanced to -10. The total was also on the move, dropping from 53.5 to 52.

Oregon vs. USC Odds

  • Opening point spread: Oregon -2.5
  • Opening moneyline: Oregon TBA/USC TBA
  • Opening total: Over/Under 62.5 points scored
  • Time: 7:30 p.m. ET Saturday (NBC)

OPENING ODDS UPDATE: No. 12 USC (4-0 SU/1-3 ATS) has done what's necessary to win, but hasn't been effective at covering. In Week 3, the Trojans were hefty 21.5-point favorites at Rutgers and held on for a 42-35 victory.

No. 20 Oregon (2-1 SU/1-2 ATS) struggled in its first two games, including a huge Week 2 upset loss at Oklahoma State. The Ducks found the cure in the form of an FCS opponent.

Oregon pummeled Portland State 84-0, easily covering as a massive 59.5-point home favorite.

The Ducks opened as 2.5-point road faves at Circa Sports, and that number was rock-solid Sunday, with no movement.

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Patrick Everson

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson
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