The Belk Bowl started in 2002 and the matchup currently features schools from the Atlantic Coast Conference (ACC) and the Southeastern Conference (SEC). The game takes place at Bank of America Stadium from Charlotte, North Carolina. This game was previously called the Meineke Car Care Center Bowl and the Continental Tire Bowl before Belk obtained sponsorship rights in 2011.
Favorites had won seven straight times from 2011-2017 until Virginia wiped out South Carolina, 28-0 in 2018, followed by Kentucky rallying past Virginia Tech, 37-30 in 2019. Six of the past eight Belk Bowls have been decided by double-digits, including the infamous Cincinnati cover against Duke in 2012 when the Bearcats scored two late touchdowns to cash as nine-point favorites, 48-34.
In 2020, Duke's Mayo took over the sponsorship rights to the annual bowl game in Charlotte, retiring the Belk Bowl name. The sponsorship deal is for six years, keeping this bowl game going through 2025.
In the 2020 installment, Wisconsin picked up a 42-28 victory over Wake Forest in a Big Ten vs. ACC matchup, as the favorite cashed with an 'over' result.
On Dec. 29, 2021, the game featured a border war between North Carolina of the ACC and South Carolina of the SEC. The Gamecocks pulled off the big upset at 12.5-point underdogs, stunning the Tar Heels 38-21 as the 'over' connected. The underdog is 4-1 ATS across the past five bowls at this venue, with the 'over' also 4-1 during the five-game span.
| Year | Matchup | Line, Total | ATS Result |
| 2021 | South Carolina 38 North Carolina 21 | North Carolina -12.5, 57.5 | Underdog, Over |
| 2020 | Wisconsin 42 Wake Forest 28 | Wisconsin -10, 51.5 | Favorite, Over |
| 2019 | Kentucky 37 Virginia Tech 30 | Virginia Tech -2, 46 | Underdog, Over |
| 2018 | Virginia 28 South Carolina 0 | South Carolina -3.5, 54 | Underdog, Under |
| 2017 | Wake Forest 55 Texas A&M 52 | Wake Forest -3.5, 62.5 | Underdog, Over |
| 2016 | Virginia Tech 35 Arkansas 24 | Virginia Tech -7.5, 61.5 | Favorite, Under |
| 2015 | Mississippi State 51 N.C. State 28 | Mississippi State -6, 61.5 | Favorite, Over |
| 2014 | Georgia 37 Louisville 14 | Georgia -7, 54.5 | Favorite, Under |
| 2013 | North Carolina 39 Cincinnati 17 | North Carolina -2.5, 58 | Favorite, Under |
| 2012 | Cincinnati 48 Duke 34 | Cincinnati -9, 62.5 | Favorite, Over |
| 2011 | N.C. State 31 Louisville 24 | N.C. State -1.5, 44 | Favorite, Over |
| 2010 | USF 31 Clemson 26 | Clemson -5.5, 40.5 | Underdog, Over |
| 2009 | Pittsburgh 19 North Carolina 17 | Pick-em, 44.5 | Under |
| 2008 | West Virginia 31 North Carolina 30 | West Virginia -2.5, 47 | Underdog, Over |
| 2007 | Wake Forest 24 Connecticut 10 | Wake Forest -2, 46.5 | Favorite, Under |
| 2006 | Boston College 25 Navy 24 | Boston College -7.5, 48 | Underdog, Over |
| 2005 | N.C. State 14 USF 0 | N.C. State -3.5, 41 | Favorite, Under |
| 2004 | Boston College 37 North Carolina 24 | North Carolina -4, 51 | Underdog, Over |
| 2003 | Virginia 23 Pittsburgh 16 | Virginia -3, 56.5 | Favorite, Under |
| 2002 | Virginia 48 West Virginia 22 | West Virginia -5.5, 54 | Underdog, Over |
