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Last Updated May 12, 2022, 4:47 PM

2022 SWEET 16 PICKS, PREDICTIONS, ODDS

The 2022 Sweet Sixteen is set to begin on March 24, 2022 and conclude on March 25 with eight games for bettors to wager on in the 2022 NCAA Men's Tournament, as the Elite Eight will immediately follow on March 26 and conclude on March 27.

Check out our Futures Market daily and throughout the remainder of the NCAA Tournament. 

ODDS TO REACH SWEET 16

2022 SWEET 16 SCHEDULE

Thursday, Mar. 24

  • 4 Arkansas 74 (+9.5) vs. 1 Gonzaga 68 - Under 155.5
  • 11 Michigan 55 vs. 2 Villanova 63 (-4.5) - Under 136
  • 3 Texas Tech 73 vs. 2 Duke 78 (EVEN) - Over 137
  • 5 Houston 72 (+1.5) vs. 1 Arizona 60 - Under 146.5

Friday, Mar. 25

  • 15 Saint Peter's 67 (+13) vs. 3 Purdue - 64 - Under 134
  • 1 Kansas 66 vs. Providence - 61 (+7) - Under 141.5
  • 8 UNC 73 (+2.5) vs. 4 UCLA 66 - Under 142
  • 11 Iowa State 56 vs. 10 Miami-Florida 70 (-3.5) - Under 131.5

MOST POPULAR MARCH MADNESS TOOLS

MARCH MADNESS BETTING ODDS

The "Field of 68" is set and the Opening Odds are up for the First Four games plus each of the Regions, which are listed below:

MARCH MADNESS BETTING NEWS

The VegasInsider stable of College Basketball experts have been covering the action all season long with their betting preview and prediction pieces. They'll be providing analysis for all 67 games in the 2022 NCAA Tournament.

WHAT IS SWEET 16 BETTING IN THE NCAA TOURNAMENT?

The NCAA Tournament is one of the most frenetic times for sports betting in the United States. Each tournament round incites intense levels of wagering across the nation. Elite 8 betting and Sweet 16 betting are some of the most popular events in the basketball calendar.

Despite the now-defunct federal sports ban, March Madness betting has become a springtime staple in America. Millions of people join the NCAA bracket betting pools every year, competing to predict the Sweet 16 bracket and beyond.

Sweet 16 betting generates significant press coverage and analysis. Sweet 16 betting Is a veritable national obsession.

After the regular NCAA season ends, the NCAA tournament begins. The tournament sees 64 teams from all the regions and conferences in the NCAA face off in a single-elimination bracket. That means 64 teams become 32 after the first round, held on two different days.

The second round sees the field cut from 32 to 16 teams. That’s when the Sweet 16 betting action really picks up. March Madness betting is hot throughout the NCAA tournament. The final rounds, though, like Sweet 16 betting and Elite 8 betting, see most of the action.

While teams only need to win two games to make it to the Sweet 16 betting brackets, it’s no easy feat. The teams are tough, the seeding is merciless, and very few low-seeded teams rarely make it to this phase.

The lowest seed to make it to the Sweet 16 bracket was #12, and it has only happened once. A handful of #11 seeds have made it to this round of the tournament, but it’s exceedingly rare. The Sweet 16 bracket is dominated by the top-seeded teams every year.

After the Sweet 16 games, Elite 8 betting begins. The Elite 8 face off in the Regional Finals, before the Final Four play the National Semifinals. A couple of days later, the NCAA Championship Game determines the national champion.

NCAA TOURNAMENT SWEET 16 BETTING ODDS

There are many Sweet 16 betting markets you can play in. The odds tend to be pretty favorable overall, though they depend a lot on what betting markets you’re playing.

First, there are outright markets, such as Sweet 16 betting brackets and office pools. For these, the odds depend on how many players you’re competing with. If you can submit multiple NCAA brackets, it’s a good idea to do so. Each increases your odds of winning.

If you do submit multiple brackets, you need to be smart about it. You want diversity, and insurance against surprising Sweet 16 scores. You also want realistic brackets that each have a good chance of being precise. Cover your angles, but don’t just submit mirror opposite brackets.

Odds for Sweet 16 betting on specific matches will be available only after Selection Sunday and rounds 1 and 2 are finished. Until then, the bracket is still undetermined, and bookmakers will provide no odds.

After the match-ups are clear, Sweet 16 betting odds will be available at every online sportsbook. Odds tend to be pretty tight for most matches, as teams are usually well-paired. The odd game with a favorite will show large spreads and big payouts on the underdog.

SWEET 16 SCHEDULE & DATES

In 2022, the NCAA bracket, seeds, and field will be revealed on Selection Sunday (March 13). The First Four games will take place on March 15 and 16. The first and second rounds will play out between March 17 and March 20, at different venues.

At this point, the field will be down to the top 16 teams, and Sweet 16 betting can begin in earnest. The Sweet 16 games, or Regional Semifinals, will go down on March 24 and March 25.

Sweet 16 scores then determine which teams move on to the Elite 8, the Regional Finals. March Madness betting peaks at this point. Sweet 16 betting, Elite 8 betting, and Final Four betting are the most popular markets in the tournament.

SWEET 16 BRACKET

The Sweet 16 phase of the tournament has a predetermined bracket structure. To reach the Sweet 16, teams need to win their first and second-round games. Since the seeds determine who faces off with who, they also define the Sweet 16 bracket.

During the first round of the tournament, every region has 16 teams, seeded from #1 to #16. Opening games are between the first and last seed, the second and second to last, third and third to last, and so on.

It works out like this: #1 vs #16, #2 vs #15, #3 vs #14, #4 vs #13, #5 vs #12, #6 vs #11, #7 vs #10, #8 vs #9. In the second round, the process is repeated. The winner of the #1/#16 game vs the winner of the #8/#9 game, and so on.

The bracket ends up looking like this: 1/16 vs 8/9, 2/15 vs 7/10, 3/14 vs 6/11, 4/13 vs 5/12. That means that the first game of the second round could be a first seed facing a 9th seed, a 16th seed facing an 8th seed, or any other combination of these.

The Sweet 16 games bracket has the 1/8/9/16 bracket winner facing the 4/5/12/13 bracket winner, and the 2/7/10/15 winner playing the 3/6/11/14 winner.

SWEET 16 PROP BETS

Sweet 16 prop bets let audiences feel the excitement of the tournament with unique betting markets. Prop bets cover very specific events, either in specific matches or through the round of 16.

Some prop bets can be rather likely to hit, with consequently good odds. Others are downright wacky, with sometimes astronomical odds.

TYPES OF BETS

Some popular Sweet 16 prop bets include whether any players will make a game-winning shot at the buzzer (or whether they won’t). Others involve specific players winning the tournament's MVP award, or specific Sweet 16 scores.

Even mascots are part of the prop bet market. Oddsmakers provide odds on whether teams with animal mascots make it through the Sweet 16. There are odds for #1 seeds reaching the Final Four (or not doing so), odds for low seeds to make it in, and many other specific bets.

WHICH SPORTSBOOK SHOULD I USE TO BET ON THE SWEET SIXTEEN?

The first step is crucial. It is important to be in a state that has legalized sports betting. In recent weeks, certain states have gone live, including Louisiana and New York. You can also bet on March Madness online in New JerseyPennsylvaniaIndiana, and West Virginia, just to name a few.

So, which sportsbook should you bet with? While there’s always personal preference, certain online sportsbooks offer better welcome bonuses than others.

Amongst them all, BetMGMCaesars Sportsbook, and FanDuel stand out above the rest. Check them out today!

FINAL THOUGHTS ON SWEET 16 FOR MARCH MADNESS 2022

This 2022 March Madness will likely see considerable betting action and many dramatic games. As the tournament heats up and reaches the more advanced stages, bookmakers will provide odds on a number of markets.

Favorites this year include Gonzaga and Duke, the two powerhouse schools that will likely enter the tournament with Wooden Award contenders in Drew Timme and Paolo Banchero.

Whether you’re filling out brackets or placing prop bets, nothing beats the thrill of March Madness and Sweet 16 betting!

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