2022 College Football Betting Predictions, Picks, Odds

College Football Playoff Championship Predictions

The 2023 College Football Playoff National Championship is scheduled to take place at SoFi Stadium in Inglewood, California on Monday, January 9. Check out betting previews entering the 2022 season for best bets, win totals, futures odds, schedules, betting results and Heisman contenders for EVERY college football school.



It's no secret that the Clemson Tigers are once again ACC favorites entering 2022. Miami-Florida will look to try and dethrone the Tigers with a Heisman contending quarterback in Tyler Van Dyke. Pittsburgh is showing promise as a top dark horse in the conference with the addition of Kedon Slovis but did lose the Pickett-Addison connection.

Boston College Eagles
Clemson Tigers
Duke Blue Devils
Florida State Seminoles
Georgia Tech Yellow Jackets
Louisville Cardinals
Miami Hurricanes
North Carolina Tar Heels
North Carolina State Wolfpack
Pittsburgh Panthers
Syracuse Orange
Virginia Cavaliers
Virginia Tech Hokies
Wake Forest Demon Deacons

Big 10

Michigan and Wisconsin will be looking to spoil the Buckeye fun as Ohio State enters 2022 the favorite. The real wild card in this conference are the Nebraska Cornhuskers, who have a once promising coach on the hot seat and a talented quarterback Texas transfer in Casey Thompson.

Illinois Fighting Illini
Indiana Hoosiers
Iowa Hawkeyes
Maryland Terrapins
Michigan Wolverines
Michigan State Spartans
Minnesota Golden Gophers
Nebraska Cornhuskers
Northwestern Wildcats
Ohio State Buckeyes
Penn State Nittany Lions
Purdue Boilermakers
Rutgers Scarlet Knights
Wisconsin Badgers

Updated on 02/27/2024
Bonus Code INSIDER1000 Claim Now

Big 12

Although the Oklahoma Sooners are preseason Big 12 favorites they're no lock. Oklahoma State is expected to make some noise this year with the return of Spencer Sanders and the Texas Longhorns once again have lots of hype surrounding their offense. Both Baylor and Kansas State are top dark horses in this conference, while West Virginia welcomes Georgia transfer J.T. Daniels - an early Heisman contender.

Baylor Bears
Iowa State Cyclones
Kansas Jayhawks
Kansas State Wildcats
Oklahoma Sooners
Oklahoma State Cowboys
TCU Horned Frogs
Texas Longhorns
Texas Tech Red Raiders
West Virginia Mountaineers


USC might run away with this conference, having an unbelievable offseason with the arrivals of Lincoln Riley, Caleb Williams, Jordan Addison and Travis Dye. UCLA and Oregon will be relevant, while many are sleeping on Cameron Rising and the Utah Utes. It will be tough for teams to contend with USC however, one of the best offenses on paper nationally.

Arizona Wildcats
Arizona State Sun Devils
California Golden Bears
Colorado Buffaloes
Oregon Ducks
Oregon State Beavers
Stanford Cardinal
UCLA Bruins
USC Trojans
Utah Utes
Washington Huskies
Washington State Cougars

Updated on 02/27/2024
Bonus Code VIBONUS1500 Claim Now


Georgia and Alabama are the obvious top choices in the SEC, while both Florida and LSU are a bit of wildcards. Ole Miss reloaded at quarterback with the arrival of Jaxson Dart, while both Mississippi State and Kentucky return veteran quarterbacks with Heisman aspirations. Arkansas and South Carolina are great dark horses, but Texas A&M seems to be the legit threat to both Alabama and Georgia, if there is one.

Alabama Crimson Tide
Arkansas Razorbacks
Auburn Tigers
Florida Gators
Georgia Bulldogs
Kentucky Wildcats
LSU Tigers
Mississippi State Bulldogs
Missouri Tigers
Ole Miss Rebels
South Carolina Gamecocks
Tennessee Volunteers
Texas A&M Aggies
Vanderbilt Commodores


It will be tough for Cincinnati to repeat as conference champions, with the Houston Cougars seemingly the biggest threat to the Bearcats repeat. Clayton Tune might be the best quarterback in the conference as well, although USF welcomes Baylor transfer Gerry Bohanon and is seen as a possible dark horse this season.

Cincinnati Bearcats
ECU Pirates
Houston Cougars
Memphis Tigers
Navy Midshipmen
SMU Mustangs
Temple Owls
Tulane Green Wave
Tulsa Golden Hurricane
UCF Knights
USF Bulls

Mountain West

This will be a fun conference in 2022, as many teams have high expectations in the Mountain West. Boise State is under pressure after a let down in 2021, while Fresno State and Heisman contender Jake Haener are expected to contend for the conference title. San Diego State will once again be in the hunt, while Utah State and Air Force are deemed top dark horses. Nevada will take the biggest hit, losing quarterback Carson Strong to the NFL.

Air Force Falcons
Boise State Broncos
Colorado State Rams
Fresno State Bulldogs
Hawaii Rainbow Warriors
New Mexico Lobos
Nevada Wolf Pack
San Diego State Aztecs
San Jose State Spartans
UNLV Rebels
Utah State Aggies
Wyoming Cowboys

Updated on 02/27/2024
Bonus Code No Code Needed Claim Now


The Independents get a bad reputation for not playing in a conference, but this typically means they see a tougher schedule. BYU and Notre Dame are the obvious top teams of the Independents bunch, but both Liberty and Army have made names for themselves in recent years finishing seasons in the AP Top 25 Poll. Rinse and repeat as the above four teams will be relevant in 2022.

Army Black Knights
BYU Cougars
Liberty Flames
New Mexico State Aggies
Notre Dame Fighting Irish
UConn Huskies
UMass Minutemen


Toledo is the favorite to win the MAC this season, but this conference seems to be a toss up. Miami-Ohio, Northern Illinois and Central Michigan are expected to have good seasons. Western Michigan is a top dark horse among many, while Akron and Bowling Green are once again expected to finish near the bottom with only a handful of wins the last few years.

Akron Zips
Ball State Cardinals
Bowling Green Falcons
Buffalo Bulls
Central Michigan Chippewas
Eastern Michigan Eagles
Kent State Golden Flashes
Miami-Ohio RedHawks
Northern Illinois Huskies
Ohio Bobcats
Toledo Rockets
Western Michigan Broncos

Sun Belt

This is a very underrated conference, capable of consistent Top 25 appearances along with the capacity to upset any school in a Power 5 conference. Louisiana, Appalachian State and Coastal Carolina are national threats and could each make a case for winning the Sun Belt in 2022. To make it tougher, Marshall now enters the picture and should be viewed as an immediate threat. Georgia State is a top dark horse this season while James Madison, Old Dominion and Southern Miss also enter the conference with Marshall for their Sun Belt debuts.

Appalachian State Mountaineers
Arkansas State Red Wolves
Coastal Carolina Chanticleers
Georgia Southern Eagles
Georgia State Panthers
James Madison Dukes
Louisiana Ragin Cajuns
Marshall Thundering Herd
Old Dominion Monarchs
South Alabama Jaguars
Southern Miss Golden Eagles
Texas State Bobcats
Troy Trojans
UL-Monroe Warhawks


UTSA was a top team nationally in 2021, and have high expectations again after seeing some solid talent transfer in. UAB and Western Kentucky are also considered favorites within the conference this season. FAU is also expected to bounce back in 2022, but the top three teams should be the only considerations for conference champion until further notice.

Charlotte 49ers
FAU Owls
FIU Panthers
Louisiana Tech Bulldogs
Middle Tennessee Blue Raiders
North Texas Mean Green
Rice Owls
UAB Blazers
UTEP Miners
UTSA Roadrunners
Western Kentucky Hilltoppers